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Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening J. Venom. Anim. Toxins incl. Trop. Dis.
El-Aziz,Tarek Mohamed Abd; Khoury,Sawsan Al; Jaquillard,Lucie; Triquigneaux,Mathilde; Martinez,Guillaume; Bourgoin-Voillard,Sandrine; Sève,Michel; Arnoult,Christophe; Beroud,Rémy; Waard,Michel De.
Abstract Background Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, therefore, that animal venoms should be rich enough in sperm-modulating compounds for a drug discovery program. Our objective was to demonstrate this fact by using a sperm-based phenotypic screening to identify positive modulators from the venom of Walterinnesia aegyptia. Methods Herein, as proof of concept that venoms contain interesting compounds for sperm physiology, we fractionated Walterinnesia aegyptia snake venom by RP-HPLC and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; Walterinnesia aegyptia; Bioactive compounds; Fertility; Sperm motility; Venomics; Tandem mass spectrometry; De novo sequencing; Edman degradation.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100301
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Agronomic performance of 'Valência' orange combined with 13 rootstocks in the state of Rio Grande do Sul, Brazil PAB
Kirinus,Marines Batalha Moreno; Oliveira,Roberto Pedroso de; Silva,Pricila Santos da; Barreto,Caroline Farias; Malgarim,Marcelo Barbosa; Soares Filho,Walter dos Santos.
Abstract: The objective of this work was to evaluate the agronomic performance of 'Valência' sweet orange (Citrus sinensis) tree, in combination with 13 rootstocks cultivated in soil and climate conditions of the Brazilian state of Rio Grande do Sul. The following agronomic variables were evaluated: scion height and volume, plant production, production efficiency, productivity, fruit diameter, fruit mass, peel mass, juice yield, soluble solids content, titratable acidity, soluble solids:acidity ratio, ascorbic acid, peel color, antioxidant capacity, and phenolic compounds. A randomized complete block experimental design was used, with three replicates and nine plants per plot, in a two-factor arrangement (13 rootstocks and the 2015 and 2016 harvests). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Citrus sinensis; Bioactive compounds; Fruit quality.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-204X2019000102700
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Agronomic performance of 'Valência' orange combined with 13 rootstocks in the state of Rio Grande do Sul, Brazil. Repositório Alice
KIRINUS, M. B. M.; OLIVEIRA, R. P. de; SILVA, P. S. da; BARRETO, C. F.; MALGARIM, M. B.; SOARES FILHO, W. dos S..
bitstream/item/197746/1/Roberto-Pedroso-1678-3921-pab-54-e00461.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Citrus Sinensis; Bioactive compounds; Fruit quality.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1109329
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Análise térmica de amidos de cará-moela incorporados com extratos aquosos de erva-mate (Ilex paraguariensis). Repositório Alice
WOLFF, S. M.; SILVEIRA, A. C. da; LAZZAROTTO, M..
O amido de Dioscorea bulbifera Linn, espécie conhecida também como cará moela, é um carboidrato pouco estudado. No entanto, a incorporação de extratos de erva-mate (Ilex paraguariensis) podem adicionar propriedades que agreguem valor ao produto. Este trabalho buscou adicionar extratos aquosos de erva-mate ao amido de D. bulbifera e avaliar os efeitos nas propriedades térmicas e reológicas. Assim, o amido nativo de D. bulbifera foi obtido e tratados com extrato aquosos de erva-mate em concentrações de 1,5%, 3% e 6%. Nas curvas TG, em atmosfera de ar sintético, dois eventos foram observados, no entanto a estabilidade e as propriedades térmicas do amido não foram alteradas significativamente. As temperaturas iniciais de gelatinização dos amidos incorporados...
Tipo: Artigo em anais de congresso (ALICE) Palavras-chave: Erva mate; Composto bioativo; TG-DSC; RVA; Ilex Paraguariensis; Composto Fenólico; Antioxidante; Phenolic compounds; Bioactive compounds; Antioxidant activity.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1115122
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Antagonistic properties of some microorganisms isolated from Brazilian tropical savannah plants against Staphylococcus coagulase-positive strain J. Venom. Anim. Toxins incl. Trop. Dis.
Ratti,R. P.; Serrano,N. F. G.; Hokka,C. O.; Sousa,C. P..
Endophytic microorganisms are relatively unstudied as potential sources of novel natural products for medical and commercial exploitation. The aim of this work was to investigate some Brazilian tropical savannah trees Cassia leptophylla and Prunus spp. in order to isolate the endophytic microorganisms associated with these plants. The samples were disinfected to eliminate the epiphytic population. Colonies were diluted and displayed as drops in media and growing colonies were inactivated. Staphylococcus coagulase-positive strain was used as indicator microorganism and subjected to the antibioses test. Data showed that the microorganisms isolated from Cassia leptophylla had no inhibition against Staphylococcus. On the other hand, microorganisms isolated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Endophytic microorganisms; Plants; Antibacterial activity; Bioactive compounds.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200007
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Anthocyanin accumulation and color development of 'Benitaka' table grape subjected to exogenous abscisic acid application at different timings of ripening. Repositório Alice
SHAHAB, M.; ROBERTO, S. R.; AHMED, S.; COLOMBO, R. C.; SILVESTRE, J. P.; KOYAMA, R.; SOUZA, R. T. de.
In colored table grapes, the anthocyanin contents are inhibited by the high temperature during ripening and berries suffer a lack of skin color, thus affecting their market value. In order to overcome this issue, a research study was planned to evaluate the influence of (S)-cis-abscisic acid (S-ABA) on rates of anthocyanin accumulation in table grapes when applied at different timings of ripening, and to quantify the gradual increase of berry color. The study was conducted in a commercial vineyard of ?Benitaka? table grapes (Vitis vinifera L.), grown under double annual cropping system in a subtropical area. The trials were carried out during two consecutive seasons (i.e., summer season of 2015 and off-season of 2016). The treatments used for the...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Vitis vinifera L; Production system; S-ABA; Rate of anthocyanin accumulation; CIRG; Bioactive compounds.
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1118223
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Antibacterial activity of Falkenbergia hillebrandii (Born) from the Indian coast against human pathogens Phyton
Manilal,A; Sujith,S; Selvin,J; Shakir,C; Seghal Kiran,G.
The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial activity; F. hillebrandii; Multidrug resistant human pathogens; Methanolic extract; Bioactive compounds.
Ano: 2009 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572009000200013
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Antifungal activity of Pseudomonas frederiksbergensis CMAA 1323 isolated from the Antarctic hair grass Deschampsia antarctica. Repositório Alice
MELO, I. S. de; SOUZA, W. R.; SILVA, L. J.; SANTOS, S. N.; ASSALIN, M. R.; ZUCCHI, T. D.; QUEIROZ, S. C. do N. de.
Abstract: Aims: Epiphytic bacteria, isolated from Deschampsia antarctica, were screened for their potential to inhibit the plant pathogen Botrytis cinerea, the causal agent of gray mold disease of strawberry pseudofruits. This phytopathogenic fungus is more active and the disease is more serious in temperate climate where the temperatures are lower.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Psychrophilic bacteria; Pseudomonas frederiksbergensis; Bioactive compounds; Diketopiperazines; Deschampsia antarctica; Compostos bioativos; Botrytis cinerea; Bactéria; Controle biológico; Diketopiperazines; Deschampsia antarctica; Pseudomonas frederiksbergensis; Psychrophilic bacteria; Antifungal agents.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1054794
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Antimicrobial activity and bioactive compounds of portuguese wild edible mushrooms methanolic extracts IPB - Escola Superior Agrária
Barros, Lillian; Calhelha, Ricardo C.; Vaz, Josiana A.; Ferreira, Isabel C.F.R.; Baptista, Paula; Estevinho, Leticia M..
The antimicrobial properties of phenolic extracts of Portuguese wild edible mushroom species (Lactarius deliciosus, Sarcodon imbricatus and Tricholoma portentosum) against pathogens were investigated. The minimal inhibitory concentrations (MICs) were evaluated for the entire mushroom, the cap and the stipe, separately; the portion of the mushroom used proved to be influenced in the results obtained, which are directly correlated with the content of total phenols and flavonoids in the extracts. The growth of Grampositive bacteria (Bacillus cereus, B. subtilis,) was well inhibited by these mushrooms, while Escherichia coli (Gramnegative bacteria) was resistant. The study on the antifungal effect of these mushrooms revealed that Candida albicans and...
Tipo: Article Palavras-chave: Wild edible mushrooms; Bioactive compounds; Antimicrobial activity.
Ano: 2007 URL: http://hdl.handle.net/10198/829
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Antimicrobial, Antioxidant and Cytotoxic Activity of MarineStreptomyces parvulus VITJS11 Crude Extract BABT
Naine,S. Jemimah; Devi,C. Subathra; Mohanasrinivasan,V.; B,Vaishnavi.
The main aim of the study was to evaluate the bioactive properties of ethyl acetate crude extract of Streptomyces parvulus VITJS11 with a view to assess their therapeutic potential. The biological activity of ethyl acetate extract was tested against fungal and bacterial pathogens. The free radical scavenging potential of the crude extract was determined by DPPH assay. The chemo preventive properties of S. parvulus VITJS11 ethyl acetate extract was examined by MTT assay on HepG2 cells. The morphological, physiological and the biochemical properties of the strain S. parvulus VITJS11 was confirmed by conventional methods. Genotypic characterization was done using 16S r-DNA partial gene amplification and sequencing. The authenticity of the crude chemical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Marine actinomycetes; Streptomyces parvulusVITJS11; Antimicrobial activity; Antioxidants; Cytotoxicity; Bioactive compounds.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000200198
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Antioxidant potential and cytotoxic activity of two red seaweed species, Amansia multifida and Meristiella echinocarpa, from the coast of Northeastern Brazil Anais da ABC (AABC)
ALENCAR,DANIEL B. DE; SILVA,SUZETE R. DA; PIRES-CAVALCANTE,KELMA M.S.; LIMA,REBECA L. DE; PEREIRA JÚNIOR,FRANCISCO N.; SOUSA,MÁRCIA B. DE; VIANA,FRANCISCO A.; NAGANO,CELSO S.; NASCIMENTO,KYRIA S. DO; CAVADA,BENILDO S.; SAMPAIO,ALEXANDRE H.; SAKER-SAMPAIO,SILVANA.
Natural antioxidants found in marine macroalgae are bioactive compounds known to play an important role in the prevention of diseases associated with aging cells protecting them against the oxidative damage. The purpose of this study was to evaluate the antioxidant and cytotoxic activity of ethanolic extracts of two species of red seaweeds, Amansia multifida and Meristiella echinocarpa. In vitro antioxidant activity was determined by DPPH radical scavenging assay, ferric-reducing antioxidant power (FRAP) assay, ferrous ion chelating (FIC) assay, β-carotene bleaching (BCB) assay and total phenolic content (TPC) quantification. Cytotoxicity was evaluated with the brine shrimp Artemia sp. lethality test. The TPC values observed in the present study indicated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant; Bioactive compounds; Cytotoxic; Phenolic compounds; Rhodophyta.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100251
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Apple extract: cytotoxicity and dna protection. Repositório Alice
VIZZOTTO, M.; FERRI, N. M. L.; BIALVES, T. S.; ARAUJO, V. F.; PEREIRA, E. dos S.; KROLOW, A. C. R..
2013
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioactive compounds; Crystal violet; Comet assay.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/handle/doc/983037
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Avocado: characteristics, health benefits and uses Ciência Rural
Duarte,Patrícia Fonseca; Chaves,Marcia Alves; Borges,Caroline Dellinghausen; Mendonça,Carla Rosane Barboza.
ABSTRACT: This study aimed to present a literature review about the characteristics, applications, and potential of avocado (Persea americana). Avocado is considered one of the main tropical fruits, as it contains fat-soluble vitamins which are less common in other fruits, besides high levels of protein, potassium and unsaturated fatty acids. Avocado pulp contains variable oil content, and is widely used in the pharmaceutical and cosmetics industry, and in the production of commercial oils similar to olive oil. This fruit has been recognized for its health benefits, especially due to the compounds present in the lipidic fraction, such as omega fatty acids, phytosterols, tocopherols and squalene. Studies have shown the benefits of avocado associated to a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Avocado tree; Avocado oil; Unsaturated fatty acid; Bioactive compounds.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000400747
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Bioactive compounds and total antioxidant activity during the development of sapodilla fruit. Repositório Alice
OLIVEIRA, L. S.; RODRIGUES, D. da C.; MOURA, C. F. H.; MIRANDA, M. R. A..
2010
Tipo: Resumo em anais de congresso (ALICE) Palavras-chave: Bioactive compounds; Antioxidant activity; Sapodilla fruit.
Ano: 2010 URL: http://www.alice.cnptia.embrapa.br/handle/doc/882353
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Bioactive compounds of juices from two Brazilian grape cultivars. Repositório Alice
SILVA, J. K.; CAZARIN, C. B. B.; CORREA, L. C.; BATISTA, A. G.; FURLAN, C. P. B; BIASOTO, A. C. T.; PEREIRA, G. E.; CAMARGO, A. C. de; MARÓSTICA JUNIORA, M. R..
Grape juice consumption may prevent several chronic diseases owing to the presence of phenolic compounds, which have an important role in the reduction of oxidative stress. This study investigated the polyphenol content and antioxidant activities of grape juices from two cultivars: BRS-Cora and Isabella. Total polyphenol content (TPC), anthocyanins, antioxidant capacity (oxygenradical absorbance capacity, ferric reducing antioxidantpower and1,1-diphenyl-2-picrylhydrazyl), and phenolic profile (high-performance liquid chromatography with diode array and fluorescence detection ? HPLC-DAD-FLD) were determined.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Variedade Isabella; BRS-Cora; Uva; Suco de uva; Polifenóis; Potencial antioxidante; Compostos bioativos; Grape juice; Polyphenols; Antioxidant potential; Bioactive compounds.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1036811
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Bioactive peptides from marine sources: pharmacological properties and isolation procedures OceanDocs
Aneiros, A.; Garateix, A..
Marine organisms represent a valuable source of new compounds. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active substances in the field of the development of bioactive products. In this paper, the molecular diversity of different marine peptides is described as well as information about their biological properties and mechanisms of action is provided. Moreover, a short review about isolation procedures of selected bioactive marine peptides is offered. Novel peptides from sponges, ascidians, mollusks, sea anemones and seaweeds are presented in association with their pharmacological properties and obtainment methods.
Tipo: Journal Contribution Palavras-chave: Marine environment; Marine organisms; Peptides; Bioactive compounds; Marine environment; Peptides; Http://aims.fao.org/aos/agrovoc/c_4610; Http://aims.fao.org/aos/agrovoc/c_5691.
Ano: 2004 URL: http://hdl.handle.net/1834/2921
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Bioatividade de extratos de plantas sobre lagartas de Anticarsia gemmatalis e Helicoverpa armigera. Infoteca-e
MARINHO-PRADO, J. S.; QUEIROZ, S. C. do N. de; PRADO, S. de S.; ASSIS, M. C. de.
Resumo: Os extratos vegetais de quatro espécies das famílias Asteraceae e Verbenaceae foram avaliados quanto a bioatividade sobre as lagartas Anticarsia gemmatalis Hubner, 1818 (Lepidoptera: Erebidae) e Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae). Os extratos hexânicos, diclorometânicos, metanólicos e aquosos de Clerodendrum splendens, Conyza canadensis, Tithonia diversifolia e Vernonanthura westiniana foram oferecidos às lagartas por ingestão em ensaios, avaliando-se a biologia e o comportamento desses insetos. Os extratos vegetais de C. splendens em diclorometano e hexano e de V. westiniana em metanol avaliados sobre A. gemmatalis causaram altas taxas de mortalidade observadas nas lagartas, sendo que o extrato de C. splendens em diclorometano...
Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) Palavras-chave: Vernonanthura westiniana; Clerodendrum splendens; Extrato Vegetal; Praga de Planta; Anticarsia Gemmatalis; Helicoverpa armigera; Bioactive compounds; Conyza canadensis; Tithonia diversifolia.
Ano: 2018 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1095015
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Biochemical characterization and antioxidant activity of walnut kernel (Juglans regia L.) of accessions from Middle and High Atlas in Morocco Biological Sciences
Kabiri, Ghizlane; Bouda, Said; Elhansali, Mohammed; Haddioui , Abdelmajid.
Biochemical composition and antioxidant activity were determined in kernel nuts for eleven Moroccan walnut (Juglans regia L.) accessions representing its main cropping area. Total oil, carbohydrates, crude protein, energy value, crude fiber and flavonoid have varied significantly between accessions, respectively within the range values of 54.50-65.48%, 8.17-19.25%, 11.5-25.58%, 648.91-713.83 Kcal, 4.17-6.75% and 12.59-62.11mg RE 100 g-1 DM.  Besides, mineral composition (mg 100 g-1) of kernel have varied also significantly among accessions and particularly for phosphorus (338.1-675.87), copper (2.08-6.67), zinc (3.39-18.63), iron (1.17-2.64), chromium (0.16-0.20), nickel (1.26-1.45) and boron (0.07-1.49). However, dry matter (96.75-98.56%),...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Variation; Proximate composition; Mineral composition; Bioactive compounds.
Ano: 2019 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/46411
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Biological activities of the fermentation extract of the endophytic fungus Alternaria alternata isolated from Coffea arabica L. BJPS
Fernandes,Maurette dos Reis Vieira; Silva,Tales Alexandre Costa e; Pfenning,Ludwig Heinrich; Costa-Neto,Cláudio Miguel da; Heinrich,Tassiela Andréa; Alencar,Severino Matias de; Lima,Marisa Aparecida de; Ikegaki,Masaharu.
A total of 22 endophytic fungi isolated from coffee (Coffea arabica L.) were cultivated in vitro and their crude extracts tested. The screening was carried out using the agar diffusion method against Staphylococcus aureus, Escherichia coli and Candida albicans. The most effective isolate was Alternaria alternata, and subsequently, its extract was assayed. The total phenolic content was 3.44 μg GAE/mg of the crude extract. For the antibacterial and antifungal activity assays, minimum inhibitory concentrations (MIC) and minimum bactericidal and fungicidal concentrations (MBC and MFC) were determined. The ranges of MIC values were 50-100 μg/mL for S. aureus and 400-800 μg/mL for E. coli. The extract did not show activity in the tested concentrations for C....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Endophytic fungi; Bioactive compounds; Alternaria alternata/extract/antioxidant activity.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400010
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BOTÂNICA E FISIOLOGIA/ BOTANY AND PHYSIOLOGY ANTIOXIDANT ACTIVITY AND PHYSICOCHEMICAL PARAMETERS IN ‘CUERNAVAQUEÑA’ MEXICAN PLUM (Spondias purpurea L.) AT DIFFERENT RIPENING STAGES Rev. Bras. Frutic.
VARGAS,ADABELLA SUÁREZ; JUÁREZ-LÓPEZ,PORFIRIO; LÓPEZ-MARTÍNEZ,VÍCTOR; FLORES,LAURA JOSEFINA PÉREZ; SÁNCHEZ,DAGOBERTO GUILLÉN; ALIA-TEJACAL,IRÁN.
ABSTRACT Mexican plum (Spondias purpurea L.) ‘Cuernavaqueña’ was harvested at four ripening stages, with the aim of evaluating the concentration of bioactive compounds and antioxidant capacity in the pulp and the epicarp. The highest ethylene production (9.43 mL kg h-1) and total soluble solids concentration (23.9 °Brix) was observed in the fully ripe stage. Titratable acidity was higher in green stage compared to other analyzed ripening stages in both pulp (0.48 %) and epicarp (0.32 %). Fully ripe plum epicarp presented the highest content of total phenols (GAE 190 mg g-1), flavonoids (QE 214 mg g-1), and carotenoids (853 mg g-1) compared to other ripening stages. The antioxidant capacity was higher in the epicarp of the fully ripe fruit compared to the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Spondias purpurea; Bioactive compounds; Antioxidant activity.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452017000400203
Registros recuperados: 76
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