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Antioxidant flavonols from fruits, vegetables and beverages: measurements and bioavailability Biol. Res.
CROZIER,ALAN; BURNS,JENNIFER; AZIZ,AZLINA A; STEWART,AMANDA J; RABIASZ,HELENA S; JENKINS,GARETH I; EDWARDS,CHRISTINE A; LEAN,MICHAEL EJ.
Flavonols are polyphenolic secondary plant metabolites that are present in varying levels in commonly consumed fruits, vegetables and beverages. Flavonols have long held an interest for nutritionists, which has increased following a Dutch study in the early 1990’s showing that dietary intake of flavonols was inversely correlated with the incidence of coronary heart disease. The main factors that have hindered workers in the field of flavonol research are (i) the accurate measurement of these compounds in foods and biological samples, and (ii) a dearth of information on their absorption and metabolism. This review aims to highlight the work of the authors in attempting to clarify the situation. The sensitive and selective HPLC procedure to identify and...
Tipo: Journal article Palavras-chave: Bioavailability; Dietary antioxidants; Flavones; Flavonols; HPLC analysis.
Ano: 2000 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200007
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Bioavailability comparison of free and esterified lutein for layer hens Rev. Bras. Ciênc. Avic.
Wu,L; Huang,X; Shi,K; Tan,R.
Lutein supplements are often used to pigment and enrich layer chicken eggs. This experiment was conduced to compare the bioavailability of free and esterified lutein, by depletion method. Forty chickens were randomly divided into two groups. After 2 weeks of washout period, when all birds were fed the same low lutein basal diet, the two groups were fed for another 2 weeks with diets supplemented with free lutein or esterified lutein. Two experimental diets were supplemented with the same amount of 15 mg lutein/kg. On day 0 (baseline) and days 3, 7, and 14, birds fasting morning plasma samples were collected and stored for lutein analysis by high performance liquid chromatography method (HPLC). Results showed that: 1) Plasma lutein concentration increased...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bioavailability; Depletion method; Free lutein; Layer hens; Lutein ester.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2009000200004
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Bioavailability of Polycyclic Aromatic Hydrocarbons (PAHs) from Soil and Hay Matrices in Lactating Goats Inra
Costera, A.; Feidt, C.; Dziurla, M.A.; Monteau, F.; Le Bizec, B.; Rychen, G..
This experiment was aimed at determining the bioavailability of three polycyclic aromatic hydrocarbons(PAHs) in goats: phenanthrene, pyrene, and benzo[a]pyrene. A Latin square designprocedure was carried out involving three alpine lactating goats and three PAH-contaminatedmatrices (soil, hay, and oil as a control). Milk and urine samples were collected to assess PAH andhydroxy-PAH excretion kinetics and to compare the carry-over rates for the different matrices. PAHswere found to be excreted mainly in urine; metabolite concentrations were about 20 times higher inurine than in milk. 1-Hydroxypyrene was the major metabolite in both body fluids (8000 ng/mL urineand 450 ng/mL milk); it may be considered as a valuable indicator of the ruminant exposure toPAHs....
Tipo: Journal Article Palavras-chave: PAHs; 1-hydroxypyrene; Soil; Hay; Bioavailability; Urine; Milk; Goats.
Ano: 2009 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010b4f85ccc&uri=/notices/prodinra1/2010/06/
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Bioavailability of the sodium pertechnetate and morphometry of organs isolated from rats: study of possible pharmacokinetic interactions of a ginkgo biloba extract BABT
Moreno,Silvana Ramos Farias; Carvalho,Jorge José; Nascimento,Ana Lúcia; Pereira,Mário; Rocha,Emely Kazan; Diré,Gláucio; Arnobio,Adriano; Caldas,Luiz Querino de Araújo; Bernardo-Filho,Mario.
Many compounds affect the bioavailability of radiobiocomplexes as radiopharmaceuticals. Ginkgo Biloba extract (EGb) has several effects. The influence of an EGb on the bioavailability of the radiobiocomplex sodium pertechnetate (Na99mTcO4) and on the morphometry of the organs was evaluated. Rats were treated with EGb and Na99mTcO4 was injected. The animals were sacrificed; the radioactivity in the organs was counted. The results showed that EGb altered the Na99mTcO4 bioavailability in the kidneys, liver and duodenum. Morphometric analysis of the organs showed significant alterations (P<0.05), probably caused by metabolites generated by EGb and capable of altering the bioavailability of the Na99mTcO4.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ginkgo biloba extract; Bioavailability; Radiobiocomplex; Sodium pertechnetate; Morphometry.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700011
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Combined application of bio-organic phosphate and phosphorus solubilizing bacteria (Bacillus strain MWT 14) improve the performance of bread wheat with low fertilizer input under an arid climate BJM
Tahir,Muhammad; Khalid,Umaira; Ijaz,Muhammad; Shah,Ghulam Mustafa; Naeem,Muhammad Asif; Shahid,Muhammad; Mahmood,Khalid; Ahmad,Naveed; Kareem,Fazal.
Abstract This study was aimed to investigate the effect of bio-organic phosphate either alone or in combination with phosphorus solubilizing bacteria strain (Bacillus MWT-14) on the growth and productivity of two wheat cultivars (Galaxy-2013 and Punjab-2011) along with recommended (150–100 NP kg ha−1) and half dose (75–50 NP kg ha−1) of fertilizers. The combined application of bio-organic phosphate and the phosphorous solubilizing bacteria strain at either fertilizer level significantly improved the growth, yield parameters and productivity of both wheat cultivars compared to non-inoculated control treatments. The cultivar Punjab-2011 produced the higher chlorophyll contents, crop growth rate, and the straw yield at half dose of NP fertilizer; while...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phosphorous; Phosphorous solubilizing bacteria; Bioavailability; Rhizosphere; Low fertilizer input.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500015
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Cycle du mercure en estuaire, baie de Seine et pays de Caux ArchiMer
Laurier, Fabien.
The Seine estuary and its adjacent region Pays de Caux are two significant sources of mercury for coastal marine environments. It is carried through fluvial means for the Seine bay and through karstic fresh water emergences for Pays de Caux's coastal area. Mercury cycle in the Seine estuary and bay is affected by additional anthropical activities. The estuary's maximal turbidity area acts like a trap and a chemical reactor for fluvial mercury. Within this area, we can confirm: (i) the non conservative behaviour of dissolved mercury; (ii) mercury enrichment of particles when comparing the Seine's and marine environment and we suggest mercury particle redistribution from the organic fraction to the oxyhydroxydes fraction. A large fraction of mercury is...
Tipo: Text Palavras-chave: Bay of Seine; Pays de Caux; Estuary; Coastal zone; Speciation; Bioavailability; Mercury; Pays de Caux; Seine; Estuaire; Emergence; Zone côtière; Spéciation; Biodisponibilité; Mercure.
Ano: 2001 URL: http://archimer.ifremer.fr/doc/2001/these-1842.pdf
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Determinación del contenido de metales pesados en las fracciones geoquímicas del sedimento superficial asociado a los manglares de la Ciénaga Grande de Santa Marta, Colombia OceanDocs
Espinosa, Luisa Fernanda; Parra, Juan Pablo; Villamil, Carlos.
El ecosistema de manglar de la Ciénaga Grande de Santa Marta (CGSM) ha estado sometido a fuertes presiones antropogénicas que han ocasionado, entre otros, cambios en las características fisicoquímicas de sus sedimentos. En condiciones normales, los sedimentos asociados al manglar generan equilibrios que permiten la retención de metales pesados en distintas formas químicas, al romperse este equilibrio los metales que no son retenidos en la matriz sedimentaria, pueden ser removilizados y hacerse biodisponibles. Con el propósito de establecer el potencial de movilidad y biodisponibilidad de los metales Cr, Mn, Ni, Cu, Zn, Cd, As y Pb en sedimentos superficiales asociados al manglar en la CGSM, se analizaron sus contenidos en cuatro áreas con diferente grado...
Tipo: Journal Contribution Palavras-chave: Heavy metals; Sediments; Bioavailability.
Ano: 2011 URL: http://hdl.handle.net/1834/4379
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Development of self-nanoemulsifying tablet (SNET) for bioavailability enhancement of sertraline BJPS
Rahman,Mohammad Akhlaquer; Mujahid,Mohammad.
Abstract The purpose of the study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form. Self-nanoemulsifying drug delivery system (SNEDDS) was prepared to enhance the solubility and thus oral bioavailability of sertraline. Aqueous titration method was used to prepare the liquid SNEDDS; ternary phase diagrams were constructed and based on smaller droplet size (24.8 nm), minimum viscosity (153.63 cP) and polydispersity index (0.182), higher percentage transmittance (95%) and in vitro drug release (97%), an optimum system was designated. Liquid SNEDDS was transformed into free-flowing powder by solid adsorption technique followed by compression into tablets. In vitro release of sertraline from...
Tipo: Info:eu-repo/semantics/article Palavras-chave: SNEDDS; Phase diagrams; Solubility; Thermodynamic stability; Oral delivery; Bioavailability.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100620
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Dietary intake and health effects of selected toxic elements Braz. J. Plant Physiol.
Silva,André Luiz Oliveira da; Barrocas,Paulo R.G.; Jacob,Silvana do Couto; Moreira,Josino Costa.
Anthropogenic activities have being contributing to the spread of toxic chemicals into the environment, including several toxic metals and metalloids, increasing the levels of human exposure to many of them. Contaminated food is an important route of human exposure and may represent a serious threat to human health. This mini review covers the health effects caused by toxic metals, especially Cd, Hg, Pb and As, the most relevant toxic elements from a human health point of view.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bioavailability; Contamination; Heavy metals; Metal toxicity.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202005000100007
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Drug interaction with radiopharmaceuticals: a review BABT
Bernardo-Filho,Mario; Santos-Filho,Sebastião David; Moura,Egberto Gaspar de; Maiworm,Adalgisa Ieda; Orlando,Margarida Maria de Camões; Penas,Maria Expósito; Cardoso,Valbert Nascimento; Bernardo,Luciana Camargo; Brito,Lavínia de Carvalho.
Clinical images are worthwhile in Health Sciences and their analysis and correct interpretation aid the professionals,such as physicians, physiotherapists and occupational therapists, to make decisions and take subsequent therapeutic and/or rehabilitation measures. Other factors, besides the state of the disease, may interfere and affect the bioavailability of the radiopharmaceuticals (radiobiocomplexes) and the quality of the SPECT and PET images. Furthermore, the labeling of some of these radiobiocomplexes, such as plasma proteins, white blood cells and red blood cells, with 99mT, can also be modified. These factors include drugs (synthetic and natural) and dietary conditions, as well as some medical procedures (invasive or non-invasive), such as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Drug interaction; Blood constituents; Radiobiocomplexes; Bioavailability.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700003
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Drug interaction with radiopharmaceuticals: effect on the labeling of red blood cells with technetium-99m and on the bioavailability of radiopharmaceuticals BABT
Gomes,Maria Luisa; Oliveira,Marcia B. Nunes de; Bernardo-Filho,Mario.
The evidence that natural and synthetic drugs can affect radiolabeling or bioavailability of radiopharmaceuticals in setting of nuclear medicine clinic is already known. However, this drug interaction with radiopharmaceuticals (DIR) is not completely understood. Several authors have described the effect of drugs on the labeling of blood elements with technetium-99m (99mTc) and on the biodistribution of radiopharmaceuticals. When the DIR is known, if desirable or undesirable, the natural consequence is a correct diagnosis. However, when it is unknown, it is undesirable and the consequences are the possibility of misdiagnosis and/or the repetition of the examination with an increase of radiation dose to the patient. The possible explanation to the appearance...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Drug interaction; Blood elements; Radiopharmaceuticals; Bioavailability.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500020
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Efecto ambiental y económico-social por la aplicación de biosólidos de origen urbano como mejoradores de suelos agrícolas. Colegio de Postgraduados
González Flores, Eduardo.
La generación y disposición final de los biosólidos producidos en las plantas de tratamiento de aguas residuales, es un grave problema ambiental. La aplicación en suelos agrícolas es una opción viable por su contenido de materia orgánica, N, P y micronutrimentos. La principal restricción es su contenido de metales pesados. En la ciudad de Puebla de Zaragoza, México, los biosólidos generados se aplican en suelos agrícolas de comunidades rurales cercanas. Los suelos son delgados y de baja productividad y se cultiva principalmente maíz. El objetivo del presente trabajo fue evaluar los efectos ambientales, económicos y sociales producidos por la aplicación de biosólidos en los agroecosistemas de la comunidad La Paz Tlaxcolpan, Puebla. Se tomaron muestras de...
Palavras-chave: Metabolismo social; Biodisponibilidad; Biosólidos; Metales pesados; Agroecosistema; Social metabolism; Bioavailability; Biosolids; Heavy metals; Agroecosystem; Doctorado; EDAR; Estrategias para el Desarrollo Agrícola Regional.
Ano: 2011 URL: http://hdl.handle.net/10521/531
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Efecto ambiental y económico-social por la aplicación de biosólidos de origen urbano como mejoradores de suelos agrícolas. Colegio de Postgraduados
González Flores, Eduardo.
La generación y disposición final de los biosólidos producidos en las plantas de tratamiento de aguas residuales, es un grave problema ambiental. La aplicación en suelos agrícolas es una opción viable por su contenido de materia orgánica, N, P y micronutrimentos. La principal restricción es su contenido de metales pesados. En la ciudad de Puebla de Zaragoza, México, los biosólidos generados se aplican en suelos agrícolas de comunidades rurales cercanas. Los suelos son delgados y de baja productividad y se cultiva principalmente maíz. El objetivo del presente trabajo fue evaluar los efectos ambientales, económicos y sociales producidos por la aplicación de biosólidos en los agroecosistemas de la comunidad La Paz Tlaxcolpan, Puebla. Se tomaron muestras de...
Palavras-chave: Metabolismo social; Biodisponibilidad; Biosólidos; Metales pesados; Agroecosistema; Social metabolism; Bioavailability; Biosolids; Heavy metals; Agroecosystem; Doctorado; EDAR; Estrategias para el Desarrollo Agrícola Regional.
Ano: 2011 URL: http://hdl.handle.net/10521/531
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Evaluation of iron bioavailability in a mixture of cereals, seeds, and grains ("Human Ration") Ciênc. Tecnol. Aliment.
Enes,Bárbara Nery; Alves,Natália Elizabeth Galdino; Valdés,Samanta Thomas; Silveira,Carlos Mário Martins; Costa,Neuza Maria Brunoro; Ribeiro,Sônia Machado Rocha; Pires,Shaila Turbay; Martino,Hércia Stampini Duarte.
Iron bioavailability was evaluated in three mixtures of cereals, seeds, and grains ("Human Ration"): light, regular, and homemade provided to rats. The animals received an iron depletion diet for 21 days, followed by a repletion diet containing 12 mg·kg-1 of iron for 14 days. The hemoglobin regeneration efficiency and the relative biological value did not differ between the light mixture and control group. The iron bioavailability of the light mixture of cereals, seeds, and grains and the control group were 99.99±27.62 and 80.02±36.63, respectively, while the regular and homemade mixtures of cereals, seeds, and grains showed lower iron bioavailability, 50.12±35.53 and 66.66±15.44, respectively; the iron content of the diet with light cereal mixture light...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dietary fiber; Minerals; Bioavailability; Short chain fatty acids; Condensed tannin.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612014000100003
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Marine pollution: Let us not forget beach sand ArchiMer
Galgani, Francois; Ellerbrake, Katrin; Fries, Elke; Goreux, Chantal.
Background: Assessing the chemical or bacterial contamination in marine waters and sediments is a very common approach to evaluate marine pollution and associated risks. However, toxicity and organic pollution of beach sands have not yet been considered, except in adjacent waters. In the present study, the toxicity and the chemical contamination of natural beach sands collected 20 m from the shoreline at two sites located on the Mediterranean Sea (Marseille and La Marana, Corsica) were studied. Results: Up to 16.93% (net percentage) abnormal or dead larvae was observed in elutriates prepared from the urban beach sand sample (Marseille); no significant toxicity was observed in the sample collected from the reference beach in La Marana. Results of Fourier...
Tipo: Text Palavras-chave: Oyster larvae biotests; Sediments; Infrared spectroscopy; Gas chromatography-mass spectrometry; Microplastics; Polycyclic aromatic hydrocarbons; Mediterranean Sea; Bioavailability; Organic contaminants.
Ano: 2011 URL: http://archimer.ifremer.fr/doc/00353/46442/46186.pdf
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MOBILITY AND BIOAVAILABILITY OF HEAVY METALS AND METALLOIDS IN SOIL ENVIRONMENTS J. Soil Sci. Plant Nutr.
Violante,A; Cozzolino,V; Perelomov,L; Caporale,A.G; Pigna,M.
In soil environments, sorption/desorption reactions as well as chemical complexation with inorganic and organic ligands and redox reactions, both biotic and abiotic, are of great importance in controlling their bioavailability, leaching and toxicity. These reactions are affected by many factors such as pH, nature of the sorbents, presence and concentration of organic and inorganic ligands, including humic and fulvic acid, root exudates, microbial metabolites and nutrients. In this review, we highlight the impact of physical, chemical, and biological interfacial interactions on bioavailability and mobility of metals and metalloids in soil. Special attention is devoted to: i) the sorption/desorption processes of metals and metalloids on/from soil components...
Tipo: Journal article Palavras-chave: Bioavailability; Heavy metals; Metalloid; Adsorption; Desorption; Chemical speciation.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-95162010000100005
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Nickel adsorption and desorption in an acric oxisol as a function of pH, ionic strength and incubation time Ciência e Agrotecnologia
Mellis,Estêvão Vicari; Casagrande,José Carlos; Soares,Marcio Roberto.
ABSTRACT Although nickel (Ni) has both important potential benefits and toxic effects in the environment, its behavior in tropical soils has not been well studied. Nickel adsorption-desorption in topsoil and subsoil samples of an acric Oxisol was studied at three pH values (from 3.0 to 8.0). Adsorption-desorption isotherms were elaborated from experiments with increasing Ni concentration (5 to 100 mg L-1), during 0, 4, and 12 weeks, using CaCl2 0.01 and 0.1 M as electrolytic support in order to also verify the effect of Ni-soil time contact and of ionic strength on the reaction. Experimental results of Ni adsorption fitted Langmuir model, which indicated that maximum Ni adsorption (71,440 mg kg-1) occurred at subsoil, after 12 weeks. Nickel affinity (KL)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sorption; Bioavailability; Soil pollution; Heavy metal..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542017000100032
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Pharmacodynamic and Pharmacokinetic Studies of β-Cyclodextrin:Dexamethasone Acetate Complexes in Mice BABT
Rodrigues,Patrik Oening; Becker,Ana Cláudia; Dellagnelo,Viviane Aparecida; Benetti,Cibele Nabhan; Pereira,Eduardo Manoel; Wagner,Theodoro Marcel; Silva,Marcos Antonio Segatto.
The aim of this study was to evaluate the in vivo activity of the anti-inflammatory and analgesic effects of a suspension of the complex composed of dexamethasone acetate (DMA) with β-cyclodextrin in comparison to a suspension of the pure DMA. Solid complexes prepared by different methods were evaluated in pharmacodynamics and pharmacokinetics studies. The pharmacodynamic effect was investigated although the capacity of the inhibited the inflammation. Models of abdominal constriction, carrageenan-induced paw oedema and formalin induced licking were used. The study of the pharmacodynamic comparison of free DMA and products of β-CD:DMA demonstrated no significant difference in the majority of the tests performed. Plasma concentrations of DMA and DMA:β-CD...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Solubility; Dexamethasone acetate; Β-cyclodextrin; Bioavailability; Anti-inflammatory activity.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000600887
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PHOSPHORUS IN ORGANIC WASTE-SOIL SYSTEMS R.C. Suelo Nutr. Veg.
Fuentes,Bárbara; Bolan,Nanthi; Naidu,Ravi; Mora,María de la Luz.
Increases in the generation of organic wastes, in addition to decreases in natural resources, make it necessary to recycle these waste materials. In soils, the application of wastes as organic fertilizers, allows to reincorporate nutrients to the biogeochemical cycles. The application of wastes in agriculture has carried out with it problems associated with phosphorus (P) overapplication in soils and contamination of water bodies. Phosphorus inside the waste matrix forms organic and inorganic compounds which have different bioavailabilities. The more important factors that influence the bioavailability of P in soils, organic wastes and soil-organic waste amendments are: the soil solution pH, adsorption reactions, organic matter, phosphatase activity and...
Tipo: Journal article Palavras-chave: Phosphorus; Bioavailability; Compost; Manure.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-27912006000200006
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PREDICTION OF BIOAVAILABILITY OF CHLORPYRIFOS RESIDUES IN SOIL TO EARTHWORMS J. Soil Sci. Plant Nutr.
Wu,X.M; Yu,Y.L; Li,M; Long,Y.H; Fang,H; Li,S.N.
An incubation test was conducted to investigate the effect of aging on bioavailability of chlorpyrifos in soil and to assess the feasibility of chemical extraction techniques for predicting bioavailability of chlorpyrifos in soil. Chlorpyrifos was spiked into sterilized soil and aged in microcosms for up to 120 days. The earthworms were incubated in the spiked soils, at 0, 7, 14, 30, 60, and 120 days after spiking, for a period of 7 days. After exposure, chlorpyrifos concentrations in the earthworm tissues were determined. Change in chemical extractability of soil-chlorpyrifos was measured using a several solvent systems including methanol, methanol-water (9:1), acetone-water (5:3), and water. The results show that chemical extractability and earthworm...
Tipo: Journal article Palavras-chave: Chlorpyrifos; Residue; Soil; Earthworm; Bioavailability; Prediction.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-95162011000100004
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