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Registros recuperados: 12
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A multidisciplinary approach to the study of the fluminense vegetation Anais da ABC (AABC)
KELECOM,ALPHONSE; REIS,GEISA L.; FEVEREIRO,PAULO C.A.; SILVA,JANIE G.; SANTOS,MARCELO G.; MELLO NETO,CÍCERO B.; GONZALEZ,MARCELO S.; GOUVEA,RITA C.S.; ALMEIDA,GILBERTO S.S..
The fluminense vegetation, more specifically the flora from the Jurubatiba restinga has been investigated by a multidisciplinary team of botanists, chemist, radiobiologist, insect physiologists and geneticist. Vouchers of 564 specimens have been collected, identified, organized in an herbarium, and a database is being build up containing, in addition to classical botanical data, chemical data and information on the potential economic use either for landscape gardening, alternative foods or as medicinal plants. Phytochemical studies of the Guttiferae, Clusia hilariana, yielded oleanolic acid and nemorosone. Their biological activities against the haematophagous insect Rhodnius prolixus vector of Chagas disease have been investigated. Finally, it has been...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Taxonomy; Economic use; Oleanolic acid; Nemorosone; Polonium-210; Biological activities.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000100013
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Age-related biological activity of South American rattlesnake (Crotalus durissus terrificus) venom J. Venom. Anim. Toxins incl. Trop. Dis.
Furtado,M. F. D.; Santos,M. C.; Kamiguti,A. S..
An in vitro and in vivo comparative study was performed on the effects of Crotalus durissus terrificus venoms from a mother and its 15 newborns. The venoms were tested for protein content, lethality, proteolytic, myotoxic, hemorrhagic, and phospholipase A2 activity. The minimum coagulant dose in plasma and human fibrinogen, protrhombin, and Factor II activations were analyzed. The venoms were also analyzed by polyacrylamide gel electrophoresis (PAGE). This showed that despite similar total protein content, the biological effects of the venoms were different. Venom from young snakes exhibited higher enzymatic and coagulant activities and higher myotoxicity compared to the mother’s. In addition, the PLA2 content paralleled myotoxicity. However, no difference...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Age-related; Biological activities; Rattlesnake venom; Crotalus durissus terrificus.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992003000200005
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Antiophidian properties of plant extracts against Lachesis muta venom J. Venom. Anim. Toxins incl. Trop. Dis.
De Paula,RC; Sanchez,EF; Costa,TR; Martins,CHG; Pereira,PS; Lourenço,MV; Soares,AM; Fuly,AL.
Snakebites comprise a serious health problem in several countries due to their global incidence, which exceeds 2.5 million per year, and the elevated number of victim fatalities. To counteract envenomations, antivenoms have been used regularly for more than a century. Apart from side effects including anaphylactic reactions, antivenoms are not able to efficiently neutralize local tissue damage, which contributes to increasing the severity and morbidity observed in patients. This fact, in turn, may be responsible for economic hardship, particularly in rural populations of developing countries. In the present work, we evaluated the antiophidian properties of 12 Brazilian plant extracts against the hemolytic, coagulant, hemorrhagic and proteolytic effects of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; Lachesis muta; Plant extract; Antivenom; Biological activities.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200012
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Chemical composition, acetylcholinesterase inhibitory and antifungal activities of Pera glabrata (Schott) Baill. (Euphorbiaceae) Rev. Bras. Bot.
Cardoso-Lopes,Elaine Monteiro; Paula,Daisy Maria Bentes de; Barbo,Fausto Erritto; Souza,Amanda de; Blatt,Cecília Terumi Teradaira; Torres,Luce Maria Brandão; Young,Maria Cláudia Marx.
Pera glabrata (Schott) Baill. was selected for this study after showing a preliminary positive result in a screening of Atlantic Forest plant species in the search for acetylcholinesterase inhibitors and antifungal compounds. The bioassays were conducted with crude ethanol extract of the leaves using direct bioautography method for acetylcholinesterase and antifungal activities. This extract was partitioned with hexane, chloroform and ethyl acetate solvents. The active chloroform fraction was submitted to silica gel chromatography column affording 12 groups. Caffeine, an alkaloid, which showed detection limits of 0.1 and 1.0 µg for anticholinesterasic and antifungal activities, respectively, was isolated from group nine. After microplate analyses, only...
Tipo: Info:eu-repo/semantics/article Palavras-chave: 9-hydroxy-4-megastigmen-3-one; Biological activities; Caffeine; Euphorbiaceae.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84042009000400019
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Development and evaluation of an inhalation chamber for in vivo tests Anais da ABC (AABC)
SILVA,EDUARDO R. DA; BIZZO,HUMBERTO R.; FERNANDES,PATRÍCIA D.; VEIGA JUNIOR,VALDIR F. DA; LEITÃO,SUZANA G.; OLIVEIRA,DANILO R. DE.
ABSTRACT The bioavailability, toxicity, and therapeutic efficacy of a drug is directly related to its administration route. The pulmonary route can be accessed by inhalation after fumigation, vaporization or nebulization. Thus, pharmacological and toxicological evaluation accessed by an apparatus specifically designed and validated for this type of administration is extremely important. Based on pre-existing models, an inhalation chamber was developed. This presents a central structure with five animal holders. The nebulized air passes directly and continuously through these holders and subsequently to an outlet. Evaluation of its operation was performed using clove essential oil, a nebulizer, and a flow meter. The air within the chamber was collected by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Biological activities; Gas chromatograph; Headspace; Inhalation chamber; Syzygium aromaticum.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401643
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EFFECT OF LIQUID COW MANURE ON CHEMICAL AND BIOLOGICAL PROPERTIES IN AN ANDISOL R.C. Suelo Nutr. Veg.
Aguilera,Paula; Briceño,Gabriela; Mora,María de la Luz; Demanet,Rolando; Palma,Graciela.
The aim of this work was to establish the effect of the dose of liquid cow manure (LCM) on some chemical properties and biological activity in an Andisol. This study was carried out under laboratory conditions using an Andisol and LCM from a dairy farm located in the South of Chile. The dose of LCM were the equivalent to 0 (SO), 100 (S100), 200, (S200) and 300 (S300) thousand L ha-1. This amount is equivalent to regular agronomic LCM applications. The chemical characterization indicated that the LCM addition modified all the tested Andisol chemical properties. These begin to return to the initial conditions from 10 days on, with the exception of EC, K and DOC. The C-C0(2) evolution indicated that LCM incorporation at increasing dose enhanced the...
Tipo: Journal article Palavras-chave: Liquid amendment; Biological activities; Chemical analysis.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-27912010000200007
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General characterization of venom from the Moroccan snakes Macrovipera mauritanica and Cerastes cerastes J. Venom. Anim. Toxins incl. Trop. Dis.
Oukkache,N; Lalaoui,M; Ghalim,N.
Ophidian envenomation accidents constitute a serious public health problem in many countries around the globe. Over 5 million such accident cases occur each year causing more than 100,000 deaths. In Africa, more than 20,000 deaths per year are registered while 400,000 envenomation victims retain severe and permanent functional sequelae. In Morocco, snakebites are frequent and of greater severity in children. They occur mostly in rural areas. The incidence of these bites remains poorly understood and vastly underestimated. The epidemiological data are not well known due to the absence of a national registry, whereas a significant proportion of envenomations receive only traditional treatment methods in non-medical intensive care. This prompted us to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cerastes cerastes; Macrovipera mauritanica; Snake venom; Characterization; Biological activities; Cross-reaction.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000400009
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Lipophilic constituents and some biological activities of hexanic extracts from Zaluzania montagnifolia, (SCH. BIP.) SCH. BIP. (Asteraceae) Agrociencia
Villa-Ruano,Nemesio; Pacheco-Hernández,Yesenia; Lozoya-Gloria,Edmundo; Rubio-Rosas,Efraín; Ruiz-González,Nancy; Martínez-Orea,Yuriana; Cruz-Duran,Ramiro; Ramirez-Garcia,S. Alberto; Ramón-Canúl,L. Guadalupe.
Zaluzania montagnifolia, an antidiabetic and abortive shrub 1 to 3 m high, grows actively in xeric scrublands in some states of México. Zulazanins and some flavonoids are the foremost constituents of the polar extracts in this species; however, there is no available information about the lipophilic compounds from non-polar extracts. The objective of this study was to describe the gas chromatography-mass spectrometry (GC-MS) profile of hexanic preparations, exclusivelly with dissolve lipophilic molecules, in order to sustain the empirical uses and the new biological activities reported in this study for the plant. These preparations were obtained from flowers, leaves and roots of Z. montagnifolia which were collected in Oaxaca, México, in October 2011. In...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zaluzania montagnifolia; Grandiflorenic acid; Ent-kaurenoic acid; VOC's; Biological activities.
Ano: 2013 URL: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-31952013000400003
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New enamine derivatives of lapachol and biological activity Anais da ABC (AABC)
OLIVEIRA,MAILCAR F.; LEMOS,TELMA L.G.; MATTOS,MARCOS C. DE; SEGUNDO,TACIANA A.; SANTIAGO,GILVANDETE M.P.; BRAZ-FILHO,RAIMUNDO.
A convenient synthesis of the new enamine derivatives 2-(4-morpholinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 2-(1-piperidinyl)-3-(3-methyl-2-butenyl)-1,4-naphtalenedione and 2-(1-pyrrolidinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione was carried out from natural 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (lapachol) and morpholine, piperidine and pyrrolidine. The structures of the products were established mainly by NMR analysis, including 2D experiments. Biological activities of these products were evaluated against Artemia salina, Aedes aegypti and cytotoxicity using A549 human breast cells.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lapachol; Enamine derivatives; Biological activities.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000200004
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Phenolic compound production and biological activities from in vitro regenerated plants of gherkin (Cucumis anguria L.) Electron. J. Biotechnol.
Thiruvengadam,Muthu; Chung,Ill-Min.
Background The effect of polyamines (PAs) along with cytokinins (TDZ and BAP) and auxin (IBA) was induced by the multiple shoot regeneration from leaf explants of gherkin (Cucumis anguria L.). The polyphenolic content, antioxidant and antibacterial potential were studied from in vitro regenerated and in vivo plants. Results Murashige and Skoog (MS) medium supplemented with 3% sucrose containing a combination of 3.0 µM TDZ, 1.0 µM IBA and 75 µM spermidine induced maximum number of shoots (45 shoots per explant) was achieved. Regenerated shoots elongated in shoot elongation medium containing 1.5 µM GA3 and 50 µM spermine. The well-developed shoots were transferred to root induction medium containing 1.0 µM IBA and 50 µM putrescine. Rooted plants were...
Tipo: Journal article Palavras-chave: Biological activities; Cucumis anguria; Multiple shoot induction; Plant growth regulators; Polyamines; Polyphenolic content.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000400007
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Secondary metabolites from marine microorganisms Anais da ABC (AABC)
KELECOM,ALPHONSE.
After 40 years of intensive research, chemistry of marine natural products has become a mature field. Since 1995, there are signals of decreased interest in the search of new metabolites from traditional sources such as macroalgae and octocorals, and the number of annual reports on marine sponges stabilized. On the contrary, metabolites from microorganisms is a rapidly growing field, due, at least in part, to the suspicion that a number of metabolites obtained from algae and invertebrates may be produced by associated microorganisms. Studies are concerned with bacteria and fungi, isolated from seawater, sediments, algae, fish and mainly from marine invertebrates such as sponges, mollusks, tunicates, coelenterates and crustaceans. Although it is still to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteria; Fungi; Alkaloids; Despsipeptides; Terpenoids; Acetogenins; Biological activities.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000100012
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Taxonomic study and partial characterization of antimicrobial compounds from a moderately halophilic strain of the genus Actinoalloteichus BJM
Boudjelal,Farida; Zitouni,Abdelghani; Mathieu,Florence; Lebrihi,Ahmed; Sabaou,Nasserdine.
A moderately halophilic actinomycete strain designated AH97 was isolated from a saline Saharan soil, and selected for its antimicrobial activities against bacteria and fungi. The AH97 strain was identified by morphological, chemotaxonomic and phylogenetic analyses to the genus Actinoalloteichus. Analysis of the 16S rDNA sequence of strain AH97 showed a similarity level ranging between 95.8% and 98.4% within Actinoalloteichus species, with A. hymeniacidonis the most closely related. The comparison of the physiological characteristics of AH97 with those of known species of Actinoalloteichus showed significant differences. Strain AH97 showed an antibacterial and antifungal activity against broad spectrum of microorganisms known to be human and plant...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Actinoalloteichus; Taxonomy; Biological activities; Structure; Dioctyl phthalate.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300002
Registros recuperados: 12
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