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| Registros recuperados: 10 | |
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| Duval, David; Pichon, Rémi; Lassalle, Damien; Laffitte, Maud; Gourbal, Benjamain; Galinier, Richard. |
| Thioester-containing proteins (TEPs) superfamily is known to play important innate immune functions in a wide range of animal phyla. TEPs are involved in recognition, and in the direct or mediated killing of several invading organisms or pathogens. While several TEPs have been identified in many invertebrates, only one TEP (named BgTEP) has been previously characterized in the freshwater snail, Biomphalaria glabrata. As the presence of a single member of that family is particularly intriguing, transcriptomic data and the recently published genome were used to explore the presence of other BgTEP related genes in B. glabrata. Ten other TEP members have been reported and classified into different subfamilies: Three complement-like factors (BgC3-1 to BgC3-3),... |
| Tipo: Text |
Palavras-chave: Biomphalaria glabrata; Thioester-containing protein; Alternative splicing; Immunity; Schistosome. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00601/71268/69657.pdf |
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| Coustau, C.; Gourbal, B.; Duval, D.; Yoshino, T. P.; Adema, C. M.; Mitta, Guillaume. |
| This review summarizes the research progress made over the past decade in the field of gastropod immunity resulting from investigations of the interaction between the snail Biomphalaria glabrata and its trematode parasites. A combination of integrated approaches, including cellular, genetic and comparative molecular and proteomic approaches have revealed novel molecular components involved in mediating Biomphalaria immune responses that provide insights into the nature of host-parasite compatibility and the mechanisms involved in parasite recognition and killing. The current overview emphasizes that the interaction between B. glabrata and its trematode parasites involves a complex molecular crosstalk between numerous antigens, immune receptors, effectors... |
| Tipo: Text |
Palavras-chave: Biomphalaria glabrata; Schistosoma mansoni; Echinostoma caproni; Immunity; Compatibility. |
| Ano: 2015 |
URL: https://archimer.ifremer.fr/doc/00276/38718/38622.pdf |
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| Leyton,Vilma; Henderson,Thomas O.; Mascara,Douglas; Kawano,Toshie. |
| Foram obtidos extratos aquosos e alcoólicos a partir de pó de folhas secas de tomateiro (Lycopersicon esculentum, Mill.) c.v. Cereja. Por extração metanólica e precipitação alcalina, foi obtido um produto que denominamos "glicoalcalóide esteroidal bruto" (GEb), no qual foi caracterizada a presença de tomatina. Em ensaios laboratoriais, os extratos aquosos, alcoólicos e o GEb apresentaram atividade moluscicida em Biomphalaria glabrata (Say, 1818). O "glicoalcalóide esteroidal bruto" apresentou alta atividade moluscicida (CL50 = 8,01 ppm e CL90 = 13,17 ppm), comparável à atividade da tomatina. Desovas de B. glabrata mostraram-se resistentes aos extratos testados. Os níveis de atividade moluscicida apresentados pelos diversos extratos e o GEb, apontam apenas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Moluscicida; Biomphalaria glabrata; Lycopersicon esculentum; Tomateiro. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212005000200012 |
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| Portet, Anais; Galinier, Richard; Pinaud, Silvain; Portela, Julien; Nowacki, Fanny; Gourbal, Benjamin; Duval, David. |
| Insect thioester-containing protein (iTEP) is the most recently defined group among the thioester-containing protein (TEP) superfamily. TEPs are key components of the immune system, and iTEPs from flies and mosquitoes were shown to be major immune weapons. Initially characterized from insects, TEP genes homologous to iTEP were further described from several other invertebrates including arthropods, cniderians, and mollusks albeit with few functional characterizations. In the freshwater snail Biomphalaria glabrata, a vector of the schistosomiasis disease, the presence of a TEP protein (BgTEP) was previously described in a well-defined immune complex involving snail lectins (fibrinogen-related proteins) and schistosome parasite mucins (SmPoMuc). To... |
| Tipo: Text |
Palavras-chave: Thioester-containing protein; Complement-like protein; Biomphalaria glabrata; Interaction host/pathogens; Innate immunity. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00444/55548/71780.tif |
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| RIVERO-WENDT, C. L. G.; BORGES, A. C.; OLIVEIRA FILHO, E. C. de; MIRANDA-VILELA, A. L.; FERREIRA, M. F. N.; GRISOLIA, C. K.. |
| 17-α-methyltestosterone (MT) is a synthetic hormone used in fish hatcheries to induce male monosex. Snails hold promise as possible test models to assess chemicals acting on the endocrine system. Biomphalaria glabrata is an aquatic gastropod mollusk (Pulmonata, Planorbidae) that can be easily maintained in aquaria, predisposing the species for use in ecotoxicological testing. This study evaluated the reproductive effects of MT on B. glabrata by examining histological changes and its reproductive performance. Ten snails per group were exposed for 4 weeks to different concentrations of MT (0.01, 0.1, and 1.0 mg/L). The total number of laid eggs, egg mass per group, size of type V oocytes, and production of spermatozoids were determined. Reproduction... |
| Tipo: Artigo em periódico indexado (ALICE) |
Palavras-chave: Hormônio sintético; Performance reprodutiva; Desreguladores endócrinos; Histopatologia; Methyltestosterone; Reproductive performance; Endocrine-disrupting chemicals; Biomphalaria glabrata; Histopathology; Synthetic hormones. |
| Ano: 2014 |
URL: http://www.alice.cnptia.embrapa.br/handle/doc/1002535 |
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| Lassalle, Damien; Tetreau, Guillaume; Pinaud, Silvain; Galinier, Richard; Crickmore, Neil; Gourbal, Benjamain; Duval, David. |
| Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive. The mechanisms of recognition are quite well understood in Biomphalaria glabrata, but immune effectors have been seldom described. In this study, we analyzed a new family of potential immune effectors and characterized five new genes that were named Glabralysins. The five Glabralysin genes showed different genomic structures and the high degree of amino acid identity between the Glabralysins, and the presence of the conserved ETX/MTX2 domain, support the hypothesis that they are pore-forming toxins. In addition, tertiary structure prediction confirms that... |
| Tipo: Text |
Palavras-chave: Pore-forming toxin; Cry toxin; Invertebrate; Biomphalaria glabrata; Host; Pathogen; Vector snail; Innate immunity. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00601/71267/69655.pdf |
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| Registros recuperados: 10 | |
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