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Anti-coagulase-negative Staphylococcus activity of ethanolic extracts of propolis from two Brazilian regions and synergism with antimicrobial drugs by the E-test method J. Venom. Anim. Toxins incl. Trop. Dis.
Mantovani,R. P.; Rall,V. L. M.; Batalha,J. E. N.; Fernandes,A. A. H.; Fernandes Junior,A..
Propolis is a natural resinous substance collected by bees from vegetal sources and its therapeutic properties have been investigated. In this work, we evaluated the inhibitory activity of ethanolic extracts of propolis (EEP) from the Southeast and South of Brazil on coagulase-negative Staphylococcus (CNS) growth as well as the EEP in vitro synergism with antimicrobial drugs by using the diffusion method (E-test). The EEP chemical characteristics (dry weight, pH, flavonoid and phenolic compounds) were determined. Seven drugs were tested, and synergism was observed between three drugs and Southeast EEP, six drugs and South EEP, and one drug and ethanol control. Ethanolic extracts of propolis from the South of Brazil presented the greatest flavonoid content...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazilian propolis; Coagulase-negative Staphylococcus; E-test; Antimicrobial drugs; Synergism.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200012
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Propolis effect on streptozotocin-induced diabetic rats J. Venom. Anim. Toxins incl. Trop. Dis.
Sartori,DRS; Kawakami,CL; Orsatti,CL; Sforcin,JM.
Propolis is one of the hive products that has been used extensively in folk medicine, due to its several biological and pharmacological properties. Besides, propolis-containing products have been intensely marketed by the pharmaceutical industry and health-food stores. This work was carried out in order to investigate whether propolis treatment could revert the metabolic alterations of streptozotocin-induced diabetic rats. Animals were kept in metabolic cages and diabetes was induced by a single dose of streptozotocin (35 mg/kg, IV). After a week, rats with glycemia higher than 230 mg/dL were divided into two groups and treated with ethanolic extract of propolis (10 and 90 mg/kg, PO) for seven days. Glycemia and free fatty acids were determined, as well as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazilian propolis; Diabetes; Glucose; Free fatty acids.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000100009
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