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Registros recuperados: 19 | |
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Sanchis, D.; Fleury, C.; Chomiki, N.; Goubern, M.; Huang, Q.; Neverova, M.; Grégoire, F.; Easlick, J.; Raimbault, S.; Lévi-Meyrueis, C.; Miroux, B.; Collins, S.; Seldin, M.; Richard, D.; Warden, C.; Bouillaud, F.; Ricquier, D.. |
Tipo: Journal Article |
Palavras-chave: OXOGLUTARATE; SEQUENCE D'ACIDE AMINE; CERVEAU; SYSTEME NERVEUX CENTRAL; RESPIRATION CELLULAIRE; SPHEROBLASTE; LOCALISATION DE GENE; EXPRESSION DES GENES. |
Ano: 1998 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PUB9900008687075903&uri=/notices/prodinra1/2010/09/ |
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Cao, L.; Grova, N.; Muller, C.P.; Schroeder, H.. |
Environmental pollutants such as benzo(a)pyrene (BaP) produce numerous deficits related to central deficiencies, including decreased motor activity, neuromuscular and autonomic abnormalities. While the carcinogenicity of BaP is well established, its neurotoxic effects have received less attention. Recently, some authors predicted the neurotoxic potential of polycyclic aromatic hydrocarbon particles deposited within the brain, and their subsequent adverse effects on development. Currently, the relationship between BaP, the cerebral metabolism of xenobiotics, and behaviour has received little attention. Therefore, we focused the present study on the effects of an oral subacute BaP administration (0.02, 0.2, 2, 20 and 200 mg/kg/day, 10 days) on the regional... |
Tipo: Journal Article |
Palavras-chave: BENZO(A)PYRENE; EFFET NEUROTOXIQUE; CERVEAU; ANXIETE; GENE CYP1A1 ANXIETY-RELATED; CYP1A1. |
Ano: 2009 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD201087529f1&uri=/notices/prodinra1/2011/06/ |
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Trujillo-Cenóz, O.; Melamed, J.. |
The pedunculate bodies consist of three fibrillar regions: calyces, stalk, and roots. A group of small association neurons (the globule cells) lies within and around the calyces. The synaptic region of the calyces shows, under the phase contrast microscope, small, dense circumscribed areas of neuropil corresponding to the so-called “glomeruli” of light microscopists. The electron microscope demonstrated that each glomerulus consists of a large central nerve ending and several thin peripheral fibers. The central ending is filled with small vesicles. Mitochondria and dense granules are found intermixed with the vesicular material. The peripheral fibers contain mitochondria, slender tubules, and a few vesicles. The origin of the central ending and... |
Tipo: Journal Article-postprint |
Palavras-chave: INSECT; BRAIN; NEURONE; PEDUNCULATE BODY; CALYCE; ELECTRON MICROSCOPE; INSECTE; CERVEAU. |
Ano: 1962 |
URL: http://hdl.handle.net/2174/513 |
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Palin, K.; Moreau, M. L..; Sauvant, J.; Orcel, H.; Nadjar, A.; Duvoid-Guillou, A.; Dudit, J.; Rabié, A.; Moos, F.. |
The increase of plasma arginin-vasopressin (AVP) release, which translates hypothalamic AVP neuron activation in response to immune challenge, appears to occur independently of plasma osmolality or blood pressure changes. Many studies have shown that major inflammatory mediators produced in response to peripheral inflammation, such as prostaglandin (PG)-E2 and interleukin (IL)-1β, excite AVP neurons. However, in vivo electrical activation of AVP neurons was still not assessed in relation to plasma AVP release, osmolality, or blood pressure or to the expression and role of inflammatory molecules like PG-E2, IL-1β, IL-6, and tumor necrosis factor-{alpha} (TNF{alpha}). This study aims at elucidating those factors that underlie the activation of AVP neurons in... |
Tipo: Journal Article |
Palavras-chave: HORMONE ANTIDIURÉTIQUE; NEURONE; CERVEAU; DIURÈSE; OSMOLALITÉ; PRESSION ARTÉRIELLE; NOYAU SUPRA-OPTIQUE; PLASMA; PROSTAGLANDINE; INTERLEUKINE; FACTEUR DE NÉCROSE TUMORALE; ACTIVATION DES NEURONES LIPOPOLYSACCHARIDE INDUCED-HYPOTHALAMIC VASOPRESSIN NEURON ACTIVATION; BRAIN CYTOKINES; DIURESIS; PLASMA OSMOLALITY; BLOOD PRESSURE. |
Ano: 2009 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009179193ce&uri=/notices/prodinra1/2010/09/ |
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Paban, V.; Jaffard, M.; Chambon, C.; Malafosse, M.; Alescio-Lautier, B.. |
The present experiment was designed to study changes in behavior following immunolesioning of the basal forebrain cholinergic system. Rats were lesioned at 3 months of age by injection of the 192 IgG-saporin immunotoxin into the medial septum area and the nucleus basalis magnocellularis, and then tested at different times after surgery (from days 7-500) on a range of behavioral tests, administered in the following order: a nonmatching-to-position task in a T-maze, an object-recognition task, an object-location task, and an open-field activity test. The results revealed a two-way interaction between post-lesion behavioral testing time and memory demands. In the nonmatching-to-position task, memory deficits appeared quite rapidly after surgery, i.e. at a... |
Tipo: Journal Article |
Palavras-chave: SAPORINE; TROUBLE DE MEMOIRE; LESION; CERVEAU; TACHE D'APPARIEMENT; TEST COGNITIF; RECONNAISSANCE D'OBJETS; EMPLACEMENT DES OBJETS 192 IgG-SAPORIN; MEMORY; NONMATCHING-TO-POSITION; OBJECT-RECOGNITION; OBJECT-LOCATION. |
Ano: 2005 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD20069fc97496&uri=/notices/prodinra1/2007/07/ |
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Registros recuperados: 19 | |
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