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Registros recuperados: 11
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Antifungal activity of the ethanolic extracts of Punica granatum L. and evaluation of the morphological and structural modifications of its compounds upon the cells of Candida spp. BJM
Anibal,Paula Cristina; Peixoto,Iza Teixeira Alves; Foglio,Mary Ann; Höfling,José Francisco.
Ethanolic crude extracts prepared from the arils and seeds, pericarp, peels and from the whole fruit of Punica granatum, known as pomegranate, had their antifungal activity tested against Candida spp. The ethanolic crude extracts were analyzed by Mass Spectrometry and yielded many compounds such as punicalagin and galladydilacton. The extracts from the pericarp and peel showed activity against Candida spp., with MICs of 125 µg/mL. The effect of pericarp and peel extracts upon the morphological and structure of C. albicans and C. krusei were examined by scanning and transmission electron microscopy, with the visualization of an irregular membrane and hyphae, formation of vacuoles and thickening of the cell wall. The data obtained revealed potential...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Punica granatum; Punicalagin; Antifungal activity; Candida spp.; Electron microscopy.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300027
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Azole resistance in Candida spp. isolated from Catú Lake, Ceará, Brazil: an efflux-pump-mediated mechanism BJM
Brilhante,Raimunda S.N.; Paiva,Manoel A.N.; Sampaio,Célia M.S.; Castelo-Branco,Débora S.C.M.; Teixeira,Carlos E.C.; Alencar,Lucas P. de; Bandeira,Tereza J.P.G.; Monteiro,André J.; Cordeiro,Rossana A.; Pereira-Neto,Waldemiro A.; Sidrim,José J.C.; Moreira,José L.B.; Rocha,Marcos F.G..
Abstract Since, there is no study reporting the mechanism of azole resistance among yeasts isolated from aquatic environments; the present study aims to investigate the occurrence of antifungal resistance among yeasts isolated from an aquatic environment, and assess the efflux-pump activity of the azole-resistant strains to better understand the mechanism of resistance for this group of drugs. For this purpose, monthly water and sediment samples were collected from Catú Lake, Ceará, Brazil, from March 2011 to February 2012. The obtained yeasts were identified based on morphological and biochemical characteristics. Of the 46 isolates, 37 were Candida spp., 4 were Trichosporon asahii, 3 were Cryptococcus laurentii, 1 Rhodotorula mucilaginosa, and 1 was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aquatic environments; Yeast microbiota; Candida spp.; Antifungal resistance.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000100033
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Candida glabrata among Candida spp. from environmental health practitioners of a Brazilian Hospital BJM
Savastano,Catarina; Silva,Elisa de Oliveira; Gonçalves,Lindyanne Lemos; Nery,Jéssica Maria; Silva,Naiara Chaves; Dias,Amanda Latercia Tranches.
Abstract The incidence of the species Candida albicans and non-albicans Candida was evaluated in a Brazilian Tertiary Hospital from the environment and health practitioners. In a 12-month period we had a total positivity of 19.65% of Candida spp. The most recurring non-albicans Candida species was C. glabrata (37.62%), generally considered a species of low virulence, but with a higher mortality rate than C. albicans. Subsequently, C. parapsilosis (25.74%) and C. tropicalis (16.86%) were the second and third most commonly isolated species. Considering the total samples collected from the emergency room and from the inpatient and the pediatric sector, 19.10% were positive for Candida spp., with the predominance of non-albicans Candida species (89.42%). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida glabrata; Candida spp.; Non-albicans Candida species; Hospital environment; Antifungal drugs.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000200367
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Candida species biofilm and Candida albicans ALS3 polymorphisms in clinical isolates BJM
Bruder-Nascimento,Ariane; Camargo,Carlos Henrique; Mondelli,Alessandro Lia; Sugizaki,Maria Fátima; Sadatsune,Terue; Bagagli,Eduardo.
Over the last decades, there have been important changes in the epidemiology of Candida infections. In recent years, Candida species have emerged as important causes of invasive infections mainly among immunocompromised patients. This study analyzed Candida spp. isolates and compared the frequency and biofilm production of different species among the different sources of isolation: blood, urine, vulvovaginal secretions and peritoneal dialysis fluid. Biofilm production was quantified in 327 Candida isolates obtained from patients attended at a Brazilian tertiary public hospital (Botucatu, Sao Paulo). C. albicans ALS3 gene polymorphism was also evaluated by determining the number of repeated motifs in the central domain. Of the 198 total biofilm-positive...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida spp.; Biofilm; ALS3 gene.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400030
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Candida spp.: manual identification (reference method) and automated identification (Vitek system platform) J. Venom. Anim. Toxins incl. Trop. Dis.
Mondelli,AL; Niéro-Melo,L; Bagagli,E; Camargo,CH; Bruder-Nascimento,A; Sugizaki,MF; Carneiro,MV; Villas Boas,PJF.
Yeasts are becoming a common cause of nosocomial fungal infections that affect immunocompromised patients. Such infections can evolve into sepsis, whose mortality rate is high. This study aimed to evaluate the viability of Candida species identification by the automated system Vitek-Biomerieux (Durham, USA). Ninety-eight medical charts referencing the Candida spp. samples available for the study were retrospectively analyzed. The system Vitek-Biomerieux with Candida identification card is recommended for laboratory routine use and presents 80.6% agreement with the reference method. By separate analysis of species, 13.5% of C. parapsilosis samples differed from the reference method, while the Vitek system wrongly identified them as C. tropicalis, C....
Tipo: Info:eu-repo/semantics/other Palavras-chave: Candidemia; Candida spp.; Identification; Automated identification.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300011
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Candidiasis in pediatric patients with cancer interned in a university hospital BJM
Parahym,Ana Maria Rabelo De Carvalho; Melo,Luciana Resende Bandeira de; Morais,Vera Lúcia Lins De; Neves,Rejane Pereira.
Fungi are common causes of infection in immunocompromised patients. Candida species are frequently involved in these cases. In order to investigate candidiasis in pediatric patients with cancer, clinical samples were collected from one hundred and twenty two patients interned in the Oswaldo Cruz University Hospital in Recife, Brazil. Yeasts were isolated from thirty-four clinical samples. The species isolated were: Candida albicans (fourteen isolates), C. parapsilosis (nine isolates), C. guilliermondii (two isolates) and C. tropicalis (two isolates). We found that candidemia was most frequent in patients with malignant hematology and that C. parapsilosis infections caused the highest mortality.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida spp.; Fungi infection; Candidaemia; Pediatric patient; Cancer.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000200020
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Clinical and mycological analysis of dog's oral cavity BJM
Santin,Rosema; Mattei,Antonella Souza; Waller,Stefanie Bressan; Madrid,Isabel Martins; Cleff,Marlete Brum; Xavier,Melissa Orzechowski; Nobre,Márcia de Oliveira; Nascente,Patrícia da Silva; Mello,João Roberto Braga de; Meireles,Mário Carlos Araújo.
The oral microbiota of humans and animals is made up of a wide variety of yeasts and bacteria, but microbiota of dogs is not totally described. Although such identification is an important step to establish the etiopathogenesis and adequate therapy for the periodontal disease The aim of this study was to evaluate and correlate oral alterations with the presence of yeasts in oral cavity of female dogs. After clinical evaluation samples from healthy and from dogs with oral diseases were obtained from three different oral sites by swabs, curettes, millimeter periodontal probes and HA membrane tip in cellulose ester. Yeast identification was performed through macroscopic and microscopic colony features and biochemical tests. Dental calculus was the most...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oral microbiota; Yeasts; M. pachydermatis; Candida spp.; Halitosis.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100020
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Conventional and alternative antifungal therapies to oral candidiasis BJM
Anibal,Paula Cristina; Sardi,Janaina de Cássia Orlandi; Peixoto,Iza Teixeira Alves; Moraes,Julianna Joanna de Carvalho; Höfling,José Francisco.
Candida-associated denture stomatitis is the most common form of oral candidal infection, with Candida albicans being the principal etiological agent. Candida adheres directly or via an intermediary layer of plaque-forming bacteria to denture acrylic. Despite antifungal therapy to treat denture stomatitis, infection is reestablished soon after the treatment ceases. In addition, many predisposing factors have been identified as important in the development of oral candidiasis, including malnourishment, common endocrine disorders, such as diabetis mellitus, antibacterial drug therapy, corticosteroids, radiotherapy and other immunocompromised conditions, such as acquired immunodeficiency syndrome (AIDS). These often results in increased tolerance to the most...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida spp.; Antifungals; Medicinal plants; Extracts; Essential oil.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000400001
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Epidemiology and phospholipase activity of oral Candida spp. among patients with central nervous system diseases before and after dental cleaning procedure BJM
Ribeiro,Aurélia Silva; Silva,Dágma Aparecida; Silva,Francislene Pereira; Santos,Gleicy Carla; Campos,Lívia Maria Soares; Oliveira,Lorena Vivien Neves; Santos,Daniel Assis.
Patients suffering of diseases that affect central nervous system may be considered more susceptible to the infectious diseases of mouth. Sixty-nine patients suffering of cerebral palsy, Down's syndrome and metal retardation were submitted to saliva examination for the presence of Candida spp. before and after a procedure of dental cleaning. The isolates were submitted to assay for verifying phospholipase production. 55.10% of the patients provided isolation of Candida spp. The frequency of isolation obtained before dental procedure was: C. albicans (83.33%), C. krusei (8.33%) and C. kefyr, C. parapsilosis and C. glabrata (2.78% each). The frequency after the procedure was: C. albicans (68.57%), C. parapsilosis (11.43%), C. krusei and C. kefyr (8.57% each)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida spp.; Cerebral palsy; Down's syndrome; Metal retardation; Phospholipase.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000100004
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Mutants with heteroresistance to amphotericin B and fluconazole in Candida BJM
Claudino,A.L.R.; Peixoto Junior,R.F.; Melhem,M.S.C.; Szeszs,M.W.; Lyon,J.P.; Chavasco,J.K.; Franco,M.C..
Several studies have reported the occurrence of infections caused by Candida yeasts as well as the increasing prevalence of non albicans species. The aim of the present work is focused on the obtaining of heteroresistance to amphotericin B and fluconazole in Candida species using two distinct methodologies: selection and induction. Resistant samples were obtained by selective pressure using a medium with fluconazole for growth, followed by growth in a medium with amphotericin B. The selective pressure was also created beginning with growth in amphotericin B medium followed by growth in fluconazole medium. Concomitantly, samples were submitted to the induction of resistance through cultivation in increasing concentrations of fluconazole, followed by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amphotericin B; Antifungal agents; Candida spp.; Fluconazole; Heteroresistance; Resistant mutants.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000400028
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Oral Candida spp. colonization in human immunodeficiency virus-infected individuals J. Venom. Anim. Toxins incl. Trop. Dis.
Moris,D. V.; Melhem,M. S. C.; Martins,M. A.; Mendes,R. P..
Several yeast species of Candida genus can colonize the skin as well as the mucous membrane of the vagina and the digestive tract for short or long periods. Depending on the host's immunological state and the yeast's virulence, colonization can become an infection, invading the colonized tissues and also disseminating. AIDS is characterized by the host's intensive and progressive immunodepression which manifests as diverse symptoms, mainly lesions in the mouth. Oral candidiasis is the most prevalent opportunistic infection in individuals infected with human immunodeficiency virus (HIV) and is an important indicator of the disease progress and the immunosuppression increase. The factors involved in the equilibrium between Candida spp. and HIV-infected...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida spp.; Colonization; Human immunodeficiency virus-infected individuals.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000200004
Registros recuperados: 11
Primeira ... 1 ... Última
 

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