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| MEDINA,RODOLFO A.; OWEN,GARETH I.. |
| Mammalian cells depend on glucose as a major substrate for energy production. Glucose is transported into the cell via facilitative glucose transporters (GLUT) present in all cell types. Many GLUT isoforms have been described and their expression is cell-specific and subject to hormonal and environmental control. The kinetic properties and substrate specificities of the different isoforms are specifically suited to the energy requirements of the particular cell types. Due to the ubiquitousness of these transporters, their differential expression is involved in various disease states such as diabetes, ischemia and cancer. The majority of cancers and isolated cancer cell lines over-express the GLUT family members which are present in the respective tissue of... |
| Tipo: Journal article |
Palavras-chave: GLUT; Glucose transporters; Expression; Cancer; Estrogen; Progesterone; Cell lines. |
| Ano: 2002 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000100004 |
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| Simoni,Isabela Cristina; Fernandes,Maria Judite Bittencourt; Custódio,Renata Marconi; Madeira,Alda Maria Backx Noronha; Arns,Clarice Weis. |
| The susceptibility of the five cell lines - IB-RS-2, RK-13, Vero, BHK-21, CER - to reovirus S1133 and infectious bursal disease virus (IBDV vaccine GBV-8 strain) was studied to better define satisfactory and sensitive cell culture systems. Cultures were compared for presence of CPE, virus titers and detection of viral RNA. CPE and viral RNA were detected in CER and BHK-21 cells after reovirus inoculation and in RK-13 cell line after IBDV inoculation and with high virus titers. Virus replication by production of low virus titers occurred in IB-RS-2 and Vero cells with reovirus and in BHK-21 cell line with IBDV. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Reovirus; Infectious bursal disease virus; Cell lines; Susceptibility. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000400015 |
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