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| Topçu,I.; Çivi,M.; Öztürk,T.; Keleş,G.T.; Çoban,S.; Yentür,E.A.; Okçu,G.. |
| The effects of Ringer lactate, 6% hydroxyethyl starch (HES) (130/0.4) or 4% succinylated gelatin solutions on perioperative coagulability were measured by thromboelastography (TEG). Seventy-five patients (ASA I-III) who were to undergo major orthopedic procedures performed under epidural anesthesia were included in the study. Patients were randomly divided into three groups of 25 each for the administration of maintenance fluids: group RL (Ringer lactate), group HES (6% HES 130/0.4), and group JEL (4% gelofusine solution). Blood samples were obtained during the perioperative period before epidural anesthesia (t1, baseline), at the end of the surgery (t2), and 24 h after the operation (t3). TEG data, reaction time (R), coagulation time (K), angle value (α),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hydroxyethyl starch; Ringer lactate; Gelatin; Coagulation; Thromboelastography; Orthopedic surgery. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000900012 |
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| Boldrini-França,Johara; Pinheiro-Junior,Ernesto Lopes; Arantes,Eliane Candiani. |
| ABSTRACT Background: The prevalent class of snake venom serine proteases (SVSP) in Viperidae venoms is the thrombin-like enzymes, which, similarly to human thrombin, convert fibrinogen into insoluble fibrin monomers. However, thrombin-like serine proteases differ from thrombin by being unable to activate factor XIII, thus leading to the formation of loose clots and fibrinogen consumption. We report the functional and biological characterization of a recombinant thrombin-like serine protease from Crotalus durissus collilineatus, named rCollinein-1. Methods: Heterologous expression of rCollinein-1 was performed in Pichia pastoris system according to a previously standardized protocol, with some modifications. rCollinein-1 was purified from the culture... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snake venom; Serine proteases; Thrombin-like enzymes; Coagulation. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100306 |
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| DE JULIO,MARCELO; DE JULIO,TATIANE S.; DI BERNARDO,LUIZ. |
| This work used Fenton's reagent as a coagulating agent in the treatment of water samples with high true colour caused by humic substances (HS) extracted from peat. In addition, the effects of the apparent molecular size of HS on coagulation, flocculation and flotation were studied. To that end, four distinct water samples having the same true colour were prepared using HS with different molecular sizes, which were obtained by ultrafiltration fractioning. Through optimisation of coagulant dosage and coagulation pH, as well as posterior construction of coagulation diagrams for each water sample, it was verified that the sample prepared with the smallest apparent molecular size of HS was the most difficult to treat, requiring higher coagulant (Fenton's... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coagulation; DAF; Drinking water; Fenton's reagent; Humic substances; Molecular size. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000200833 |
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| Núñez,V.; Otero,R.; Barona,J.; Saldarriaga,M.; Osorio,R.G.; Fonnegra,R.; Jiménez,S.L.; Díaz,A.; Quintana,J.C.. |
| We determined the neutralizing activity of 12 ethanolic extracts of plants against the edema-forming, defibrinating and coagulant effects of Bothrops asper venom in Swiss Webster mice. The material used consisted of the leaves and branches of Bixa orellana (Bixaceae), Ficus nymphaeifolia (Moraceae), Struthanthus orbicularis (Loranthaceae) and Gonzalagunia panamensis (Rubiaceae); the stem barks of Brownea rosademonte (Caesalpiniaceae) and Tabebuia rosea (Bignoniaceae); the whole plant of Pleopeltis percussa (Polypodiaceae) and Trichomanes elegans (Hymenophyllaceae); rhizomes of Renealmia alpinia (Zingiberaceae), Heliconia curtispatha (Heliconiaceae) and Dracontium croatii (Araceae), and the ripe fruit of Citrus limon (Rutaceae). After preincubation of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neutralization; Edema; Defibrination; Coagulation; Bothrops asper venom; Plant extracts. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000700005 |
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| Scarpelini,S.; Rhind,S.G.; Nascimento,B.; Tien,H.; Shek,P.N.; Peng,H.T.; Huang,H.; Pinto,R.; Speers,V.; Reis,M.; Rizoli,S.B.. |
| Thromboelastography (TEG®) provides a functional evaluation of coagulation. It has characteristics of an ideal coagulation test for trauma, but is not frequently used, partially due to lack of both standardized techniques and normal values. We determined normal values for our population, compared them to those of the manufacturer and evaluated the effect of gender, age, blood type, and ethnicity. The technique was standardized using citrated blood, kaolin and was performed on a Haemoscope 5000 device. Volunteers were interviewed and excluded if pregnant, on anticoagulants or having a bleeding disorder. The TEG® parameters analyzed were R, K, α, MA, LY30, and coagulation index. All volunteers outside the manufacturer’s normal range underwent extensive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Coagulation; Thromboelastography; Normal values. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200015 |
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| Bawaskar,H. S.. |
| Snake antivenom is a specific antidote to the venom action, neutralizing the circulating venom. However, it fails to neutralize the venom fixed to target organs such as platelets, renal tubules, etc. Russell's viper venom initiates rapid coagulation in a victim by activating blood platelets, factors V, X, and anticoagulant cofactors. Activation of thrombin, resulting in formation of micro-thrombi, fibrinolysis, and a vicious cascade, sets in. Inhibition of activated platelets by aspirin (cyclooxygenase inhibitor) and clopidogrel (ADP receptor inhibitor) helps to break this vicious circle induced by Russell's venom and may initiate the natural physiological clotting mechanism. They can be utilized as an adjuvant treatment. |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Russell's viper; Coagulation; Fibrinolysis; Aspirin; Clopidogrel. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000100011 |
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| ALBUQUERQUE, M. de; RAMOS, E. M. C.; GONÇALVES, W. M. F.; BARRIGA, J. P.; BARBOSA, W. C.; SILVA, D. de A. e.. |
| Ação do tucupi como coagulante do látex da seringueira estudada sob experimento em moldes estatísticos. Ficou comprovado que o tucupi, sob qualquer dos tratamentos a que foi submetido, cru ou cozido, branco ou amarelo, de cultivares mansas ou bravas, pode perfeitamente substituir o ácido acético nos seringais, não exercendo nenhum efeito depreciativo sobre a qualidade do látex coagulado. |
| Tipo: Folhetos |
Palavras-chave: Rubber tree; Coagulação; Latex; Seringueira; Tucupi; Coagulation. |
| Ano: 1975 |
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/376677 |
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| Registros recuperados: 14 | |
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