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| Li,Meng; Liao,Yong; Chen,Min; Pan,Weihua; Weng,Lixing. |
| Cryptococcus spp. are common causes of mycoses in immunocompromised patients. To determine the drug susceptibilities of clinical Cryptococcus spp. isolates, the characteristics of 61 clinical Cryptococcus spp. complex isolates and their antifungal susceptibilities were investigated, including 52 C. neoformans and 9 C. gattii isolates collected at Shanghai between 1993 and 2009. Antifungal susceptibility of clinical isolates to amphotericin B, fluconazole, itraconazole, and flucytosine were determined by the microdilution method M27-A2 and the ATB FUNGUS 3 kit. The 90% minimum inhibitory concentration (MIC90) and susceptibility ranges were as follows: 1 (0.0625-1) µg/mL for amphotericin B, 4 (0.125-16) µg/ mL for fluconazole, 0.25 (0.0313-4) µg/mL for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Cryptococcus gattii; Antifungal agents. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200012 |
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| Gutch,Ruchi Sethi; Nawange,Shesh Rao; Singh,Shankar Mohan; Yadu,Ruchika; Tiwari,Aditi; Gumasta,Richa; Kavishwar,Arvind. |
| In this study, we present antifungal susceptibility data of clinical and environmental isolates of Central Indian Cryptococcus neoformans (Serotype A, n = 8 and n = 50 respectively) and Cryptococcus gattii (Serotype B, n = 01 and n = 04 respectively). Susceptibilities to fluconazole, itraconazole and ketoconazole were determined by using NCCLS broth micro-dilution methodology. The total number of resistant strains for fluconazole in case of C. neoformans and C. gattii showed a significant difference by using chi-square test (p < 0.05*), while considering fisher's exact p value was nonsignificant (p > 0.05). However, the total number of resistant strains for itraconazole and ketoconazole was not found statistically significant. A comparison of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus neoformans; Cryptococcus gattii; Minimum inhibitory concentration; Azoles; Central India. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401125 |
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| Luvizotto,MCR; Carreira,VS; Ferrari,HF; Ribeiro,D; Vallim,MA; Azevedo,V; Cardoso,TC. |
| A four-year-old male goat with a history of neurological disorder was euthanized. It presented uncommon nodules in the brain and lungs associated with multiple abscesses, predominantly in the spleen and liver. Histological examination of brain and lung sections revealed yeast forms confirmed to be Cryptococcus gattii after a combination of isolation and polymerase chain reaction (PCR) procedures. Moreover, Corynebacterium pseudotuberculosis infection was diagnosed by PCR of samples from the lung, spleen and liver. The present report highlights the rare concurrent infection of C. gatti and C. pseudotuberculosis in an adult goat from São Paulo state, Brazil, and indicates the necessity of surveillance in the treatment of goats with atypical pulmonary... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus gattii; Corynebacterium pseudotuberculosis; Meningoencephalitis; Goat. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300015 |
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| Cruz,Raquel Aparecida Sales da; Reis,Matheus de Oliveira; Leite Filho,Ronaldo Viana; Gonçalves,Maiara Aline; Spanamberg,Andréia; Sonne,Luciana; Ferreiro,Laerte; Pavarini,Saulo Petinatti; Driemeier,David. |
| ABSTRACT: Cryptococcus gattii is often associated with pulmonary and systemic infections in humans and animals. In this research we report a case of nasopharyngeal cryptococoma caused by C. gatti in an equine. A 10-year-old mare presented a mass obstructing the oropharynx. Macroscopically the mass was asymmetric, and was attached to the ethmoidal sinuses and obstructed the oropharynx. Histopathological examination of the mass revealed multiple yeast cells ranging from spherical to oval, 4-8μm in diameter, with some of them showing narrow base polar budding. Cryptococcus gattii growth in mycological culture (Sabouraud Dextrose Agar) and was L-canavanine-glycine-bromothymol blue Agar positive. The molecular identification confirmed the isolate as C. gattii... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycotic diseases; Crytococcosis; Equine; PCR; Cryptococcus gattii. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017001000551 |
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| Paula,Daphine Ariadne Jesus de; Silva,Lívia Kmetzsch Rosa e; Staats,Charley Christian; Vainstein,Marilene H.; Joanoni,Ana Lúcia Pinto; Nakazato,Luciano; Dutra,Valéria. |
| Cryptococcus neoformans and C. gattii are pathogenic yeasts that cause life-threatening diseases in humans and animals. Iron is an essential nutrient for virtually every organism as it functions as a cofactor in numerous essential enzymatic reactions. In the literature, the competition for iron between microbes and mammalian hosts during infection is well documented. In this study, we used representational difference analysis (RDA) in order to gain a better understanding of how C. gattii responds to iron starvation. A total of 15 and 29 genes were identified as having altered expression levels due to iron depletion after 3 h and 12 h, respectively. Of these, eight genes were identified in both libraries. The transcripts were related to many biological... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cryptococcus gattii; Iron; Representational difference analysis; Yeast. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300008 |
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