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Ordenar por: RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 8
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A routine electrocardiogram cannot be used to determine the size of myocardial infarction in the rat BJMBR
Bonilha,A.M.M.; Saraiva,R.M.; Kanashiro,R.M.; Portes,L.A.; Antonio,E.L.; Tucci,P.J.F..
Nine lead electrocardiograms of non-infarcted (N = 61) and infarcted (N = 71) female Wistar rats (200-250 g) were analyzed in order to distinguish left ventricle myocardial infarction (MI) larger than 40% (LMI) from MI smaller than 40% (SMI). MI larger than 40% clearly caused a deviation of ÂQRS and ÂT from normal values of 270-360 degrees to 90-270 degrees. Infarcted rats showed Q wave in D1 larger than 1 mm with 94% sensitivity and 100% specificity. The sum of QRS positivity in V1, V2 and V6 lower than 10 mm identified MI with 82% sensitivity and 100% specificity. The data showed that MI can be easily and reliably diagnosed by electrocardiogram in the rat. However, contradicting what is frequently believed, when specificity and sensitivity were analyzed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial infarction size; Rats; Electrocardiogram; Echocardiogram; ROC curve.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400016
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Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff Ciência Rural
Minozzo,Guilherme Augusto; Stedile,Simone Tostes de Oliveira; Sousa,Marlos Gonçalves.
ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypothyroidism; Echocardiogram; Ascending aorta; Left ventricular dilation; Heart disease.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000900602
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Food restriction induces in vivo ventricular dysfunction in spontaneously hypertensive rats without impairment of in vitro myocardial contractility BJMBR
Okoshi,K.; Fioretto,J.R.; Okoshi,M.P.; Cicogna,A.C.; Aragon,F.F.; Matsubara,L.S.; Matsubara,B.B..
Cardiac structures, function, and myocardial contractility are affected by food restriction (FR). There are few experiments associating undernutrition with hypertension. The aim of the present study was to analyze the effects of FR on the cardiac response to hypertension in a genetic model of hypertension, the spontaneously hypertensive rat (SHR). Five-month-old SHR were fed a control or a calorie-restricted diet for 90 days. Global left ventricle (LV) systolic function was evaluated in vivo by transthoracic echocardiogram and myocardial contractility and diastolic function were assessed in vitro in an isovolumetrically beating isolated heart (Langendorff preparation). FR reduced LV systolic function (control (mean ± SD): 58.9 ± 8.2; FR: 50.8 ± 4.8%, N =...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Undernutrition; Isolated heart; Echocardiogram; Langendorff preparation; Ventricular remodeling.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000400019
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Human umbilical cord blood cells in infarcted rats BJMBR
Pinho-Ribeiro,V.; Maia,A.C.V.; Werneck-de-Castro,J.P S.; Oliveira,P.F.; Goldenberg,R.C.S.; Campos de Carvalho,A.C..
Therapy with bone marrow-derived cells has been used in ischemic patients with reported success. The aim of this study was to determine the therapeutic efficacy of fresh and frozen human umbilical cord blood cells (hUCB) in Wistar rats submitted to permanent occlusion of the left coronary artery. Three hours after myocardial infarction, 2 x 10(7) hUCB cells or vehicle were administered by intramyocardial injection. The animals were divided into five groups: control (N = 10), sham operated (N = 10), infarcted that received vehicle (N = 9), infarcted treated with cryopreserved hUCB (N = 7), and infarcted treated with fresh hUCB (N = 5). Cardiac function was evaluated by electrocardiogram (ECG) and echocardiogram (ECHO) before cell therapy, and by ECG, ECHO,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cell therapy; Fresh and frozen human umbilical cord blood; Acute myocardial infarction; Electrocardiogram; Echocardiogram.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300011
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Importance of SERCA2a on early isolated diastolic dysfunction induced by supravalvular aortic stenosis in rats BJMBR
Silveira,C.F.S.M.P.; Campos,D.H.S.; Freire,P.P.; Deus,A.F.; Okoshi,K.; Padovani,C.R.; Cicogna,A.C..
Cardiac remodeling is defined as changes in shape and function of the heart in response to aggression (pressure overload). The sarcoplasmic reticulum calcium ATPase cardiac isoform 2a (SERCA2a) is a known factor that influences function. A wide spectrum of studies report a decrease in SERCA2a in heart failure, but none evaluate it's the role in early isolated diastolic dysfunction in supravalvular aortic stenosis (AoS). Our hypothesis was that SERCA2a participates in such dysfunction. Thirty-day-old male Wistar rats (60-80 g) were divided into AoS and Sham groups, which were submitted to surgery with or without aorta clipping, respectively. After 6 weeks, the animals were submitted to echocardiogram and functional analysis by isolated papillary muscle...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Papillary muscle; Echocardiogram; Cyclopiazonic acid; Rat; Isolated diastolic dysfunction; SERCA.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000500605
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Low prevalence of relevant findings in inappropriate echocardiograms and discordant perceptions between cardiologists and patients BJMBR
Lopes,J.R.; Oliveira,A.C.; Rios,V.G.; Correia,L.C.L..
Complementary examinations are “inadequate” whenever the likelihood of benefits from their indication is lower than the negative results. The low benefit is a result of poor performance in detecting relevant changes that lead to improved behavior. However, inadequate examinations are prevalent and little is known about patients' notions of the usefulness of such indications. The aim of this study was to describe relevant findings in inappropriate echocardiograms and to assess the level of agreement between patients and cardiologists regarding their usefulness. Adults without known cardiovascular disease who were referred for echocardiogram by inappropriate criteria according to the American College of Cardiology were selected. Relevant findings were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Echocardiogram; Inappropriate; Utility; Patients; Cardiologists.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800606
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Role of renin-angiotensin system in development of heart failure induced by myocardial infarction in rats Anais da ABC (AABC)
Trindade,Daniel C.; Trindade,Raquel C.; Marassi,Michelle P.; Martins,Ornélia P.P.R.; Costa-e-Sousa,Ricardo H.; Mattos,Elisabete C.; Marinho-Jr.,Alcides; Reis,Luís C.; Olivares,Emerson L..
We investigated the morphologic and functional changes of infarcted rat hearts under a paradigm of angiotensinconverting enzyme inhibition. Myocardial infarction was induced by left coronary artery ligation and a control group (SHAM) underwent sham-operation. Infarcted rats received normal drinking water with (CAP group) or without (INF group) captopril. Functional assessment was performed by electro (ECG) and echocardiogram (ECHO) just before and 21 days after surgery. The ECG of INF and CAP showed similar values and resembled healed infarct after surgery. The most outstanding differences between INF and CAP were the prevention of the increase of P-wave and attenuation both in rightward deviation of the QRS axis and Q-wave amplitude in CAP compared with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial infarction; Electrocardiogram; Echocardiogram; Renin-angiotensin system; Captopril.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000200008
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Time course of echocardiographic and electrocardiographic parameters in myocardial infarct in rats Anais da ABC (AABC)
Miranda,Amarildo; Costa-e-Sousa,Ricardo H.; Werneck-de-Castro,João P.S.; Mattos,Elisabete C.; Olivares,Emerson L.; Ribeiro,Vanessa P.; Silva,Márcia G.; Goldenberg,Regina C.S.; Campos-de-Carvalho,Antônio C..
In animal models the evaluation of myocardial infarct size in vivo and its relation to the actual lesion found post mortem is still a challenge. The purpose of the current study was to address if the conventional electrocardiogram (ECG) and/or echocardiogram (ECHO) could be used to adequately predict the size of the infarct in rats. Wistar rats were infarcted by left coronary ligation and then ECG, ECHO and histopathology were performed at 1, 7 and 28 days after surgery. Correlation between infarct size by histology and Q wave amplitude in lead L1 was only found when ECGs were performed one day post-surgery. Left ventricular diastolic and systolic dimensions correlated with infarct size by ECHO on day 7 post-infarction. On days 7 and 28 post-infarction,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial infarction; Rats; Electrocardiogram; Echocardiogram; Infarct size.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652007000400006
Registros recuperados: 8
Primeira ... 1 ... Última
 

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