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Model selection for quantitative trait loci mapping in a full-sib family Genet. Mol. Biol.
Tong,Chunfa; Zhang,Bo; Li,Huogen; Shi,Jisen.
Statistical methods for mapping quantitative trait loci (QTLs) in full-sib forest trees, in which the number of alleles and linkage phase can vary from locus to locus, are still not well established. Previous studies assumed that the QTL segregation pattern was fixed throughout the genome in a full-sib family, despite the fact that this pattern can vary among regions of the genome. In this paper, we propose a method for selecting the appropriate model for QTL mapping based on the segregation of different types of markers and QTLs in a full-sib family. The QTL segregation patterns were classified into three types: test cross (1:1 segregation), F2 cross (1:2:1 segregation) and full cross (1:1:1:1 segregation). Akaike's information criterion (AIC), the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Full-sib family; Interval mapping; Model selection; Quantitative trait locus.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000400013
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