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Registros recuperados: 51
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A SNP in the BMP3 gene associated with carcass traits in broilers. Repositório Alice
NEIS, K. L.; IBELLI, A. M. G.; MARCHESI, J. A. P.; KAWSKI, V. L.; FORNARI, M. B.; LOPES, L. dos S.; PEIXOTO, J. de O.; LEDUR, M. C..
Tipo: Separatas Palavras-chave: SNP; Carcarça.; Frango de corte; Polimorfismo genético.; Broiler chickens; Genetic polymorphism; Chicken carcasses.
Ano: 2012 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/970454
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ADRB2 polymorphisms predict the risk of myocardial infarction and coronary artery disease Genet. Mol. Biol.
Wang,Dong-Wei; Liu,Min; Wang,Ping; Zhan,Xiang; Liu,Yu-Qing; Zhao,Luo-Sha.
Abstract Recently, the rs1042713 G > A and rs1042714 C > G polymorphisms in the beta-2 adrenergic receptor (ADRB2) gene were shown to be related to atherosclerosis diseases. Therefore, we performed a systemic meta-analysis to determine whether the two functional polymorphisms are related to the risk of myocardial infarction (MI) and coronary artery disease (CAD). We identified published studies that are relevant to our topic of interest. Seven case-control studies, with a total of 6,843 subjects, were incorporated into the current meta-analysis. Our analysis showed a higher frequency of rs1042713 G > A variant in patients with MI or CAD compared to healthy controls. A similar result was also obtained with the rs1042714 C > G variant under both...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Beta-2 adrenergic receptor; Genetic polymorphism; Myocardial infarction; Coronary artery disease; Meta-analysis.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000400433
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Análise in silico para identificação de minissatélites para a cultura da mandioca (Manihot esculenta Crantz). Repositório Alice
CARMO, C. D. do; OLIVEIRA, E. J. de.
O melhoramento genético pode ser auxiliado por ferramentas moleculares tornando-o mais preciso, rápido e contornando problemas inerentes à seleção fenotípica. O uso de marcadores moleculares permite, entre outros, eliminar genótipos redundantes e quando associados a uma característica, selecionar genótipos que a expressam. Com o sequenciamento da mandioca (Manihot esculenta Crantz) (PROCHNIK et al., 2012) aliado ao uso de ferramentas da bioinformática é possível o desenvolvimento de novas ferramentas moleculares ainda limitadas para essa cultura. Sequências repetitivas de DNA são abundantes no genoma dos eucariotos presentes em regiões de heterocromatina com raros exemplos em regiões gênicas ou de regulação. Os minissatélites são sequências de 6 a 100...
Tipo: Parte de livro Palavras-chave: Mandioca; Marcador genético; Genoma; Polimorfismo genético; Cassava; Genetic markers; Genetic polymorphism; Chromosome mapping.
Ano: 2013 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/976804
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Analysis of apolipoprotein E genetic polymorphism in a large ethnic Hakka population in southern China Genet. Mol. Biol.
Zhong,Zhixiong; Wu,Heming; Wu,Hesen; Zhao,Pingsen.
Abstract There is currently no data about the genetic variations of APOE in Hakka population in China. The aim of this study was to analyze the allelic and genotypic frequencies of APOE gene polymorphisms in a large ethnic Hakka population in southern China. The APOE genes of 6,907 subjects were genotyped by the gene chip platform. The allele and genotype frequencies were analyzed. Results showed that the ∊3 allele had the greatest frequency (0.804) followed by ∊2 (0.102), and ∊4 (0.094), while genotype ∊3/∊3 accounted for 65.43% followed by ∊2/∊3 (15.85%), ∊3/∊4 (14.13%), ∊2/∊4 (3.01%), ∊4/∊4 (0.84%), and ∊2/∊2 (0.74%) in all subjects. The frequencies of the ∊4 allele in Chinese populations were lower than Mongolian and Javanese, while the frequencies of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apolipoprotein E; Genetic polymorphism; Hakka; Southern China; Genotyping.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000500742
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Analysis of genetic susceptibility to mercury contamination evaluated through molecular biomarkers in at-risk Amazon Ameridian populations. Repositório Alice
KLAUTAU-GUIMARÃES, M. de N.; D'ASCENÇÃO, R.; CALDART, F. A.; GRISOLIA, C. K.; SOUZA, J. R. de; BARBOSA, A. C.; CORDEIRO, C. M. T.; FERRARI, I..
Tipo: Separatas Palavras-chave: Amazon Amerindian; Glutathione S-transferase; Susceptibilidade genética; Biomarcador molecular; Contaminação; Mercúrio; Amazonia; Genetic polymorphism; Mercury.
Ano: 2005 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/188269
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Analysis of genetic susceptibility to mercury contamination evaluated through molecular biomarkers in at-risk Amazon Amerindian populations Genet. Mol. Biol.
Klautau-Guimarães,Maria de Nazare; D’Ascenção,Renata; Caldart,Fabiana A.; Grisolia,Cesar K.; Souza,Jurandir R. de; Barbosa,Antonio C.; Cordeiro,Célia M.T.; Ferrari,Iris.
We investigated Individual differences in susceptibility to methylmercury (MeHg) contamination and its relationship with polymorphisms of the detoxifying enzyme glutathione S-transferase (GST). In Brazil, some Amerindian tribes from the Amazon region have an increased level of mercury in their hair. Samples of hair and blood were taken from inhabitants of two villages in the Kayabi and Munduruku Amerindian communities to investigate mercury levels in association with genetic polymorphism of GSTs. Other molecular biological markers were also studied, such as hemoglobin, haptoglobin and glucose 6-phosphate dehydrogenase (G-6-PDH). Higher levels of mercury contamination were found in the Kayabi villagers, who had a null genotype (GSTM1 0/0, also denominated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amerindian; Genetic polymorphism; Glutathione S-transferase; Mercury.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500027
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ANRIL rs1333049 C/G polymorphism and coronary artery disease in a North Indian population - Gender and age specific associations Genet. Mol. Biol.
Kaur,Naindeep; Singh,Jagtar; Reddy,Sreenivas.
Abstract Many studies conducted worldwide substantiate a role of genetic polymorphisms in non-coding regions linked with coronary artery disease (CAD). One such single nucleotide polymorphism (SNP) of a non-coding RNA in the INK4 locus (ANRIL) i.e. rs1333049 C/G in the vicinity of cell cycle regulating genes is documented to have a role in CAD risk. In this study we aimed to determine the association of ANRIL rs1333049 C/G with CAD in a North Indian population. Five hundred disease free controls and 500 CAD patients were genotyped using allele specific ARMS-PCR method. High risk association of rs1333049 was seen in both heterozygous and mutant genotypes (OR=2.883, 95% CI=1.475-5.638 and p=0.002 and OR=6.717, 95% CI=3.444-13.102 and p < 0.001...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genetic polymorphism; Coronary artery disease; North Indian Population; ARMS-PCR; Epidemiology study.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000100114
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Arachis hoehnei, the probable B genome donor of Arachis hypogaea based on crossability, cytogenetical and molecular studies Open Agri
Mallikarjuna, N..
Palavras-chave: Genomes; Hybrids; Polyploidy; Cytogenetics; DNA; Groundnuts; Mosses; Genetic polymorphism; Polymorphism; Genetic improvement.
Ano: 2006 URL: http://agropedia.iitk.ac.in/openaccess/?q=node/3177
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Association between serotonin 2C receptor gene (HTR2C) polymorphisms and psychopathological symptoms in children and adolescents BJMBR
Paes,L.A.; Torre,O.H. Della; Henriques,T.B.; de Mello,M.P.; Celeri,E.H.R.V.; Dalgalarrondo,P.; Guerra Júnior,G.; dos Santos Júnior,A..
Serotonin 2C receptors (5HT2C) are involved in serotonin-driven dynamic equilibrium adjustments responsible for homeostatic stability in brain structures that modulate behavior and emotions. Single nucleotide polymorphisms (SNPs) from the serotonin 2C receptor gene (HTR2C) have been associated with several neurological and mental disorders, including abnormalities in cognitive and emotional processes. The aim of this study was to evaluate the association between the rs6318 SNP of the HTR2C gene and behavioral characteristics exhibited by children and adolescents based on the Child Behavior Checklist (CBCL/6-18) inventory. Eighty-five psychiatric outpatients between 8 and 18 years of age underwent genotyping of the rs6318 SNP. The CBCL/6-18 scale was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Genetic polymorphism; Serotonin; CBCL/6-18; Children; Adolescents; HTR2C.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800611
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Avaliação de polimorfismo em germoplasma de Tucumã (Astrocaryum vulgare Mart.) por marcadores RAPD. Repositório Alice
OLIVEIRA, E. M. de; OLIVEIRA, M. do S. P. de.
Tipo: Separatas Palavras-chave: RAPD; Tucumã.; Astrocarium vulgare; Polimorfismo genético; Variação genética; Marcador molecular; Astrocaryum vulgare.; Genetic polymorphism; Genetic variation; Random amplified polymorphic DNA technique; Genetic markers..
Ano: 2010 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1036923
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Bovine kappa-casein gene polymorphism and its association with milk production traits Genet. Mol. Biol.
Rachagani,Satyanarayana; Gupta,Ishwar Dayal.
Point mutations in exon IV of the bovine κ-casein (CSN3) gene determine two allelic variants, A and B. These variants were distinguished by polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis in the indigenous Sahiwal and Tharparkar cattle breeds. DNA samples (252 Sahiwal and 56 Tharparkar) were analyzed for allelic variants of the CSN3 gene. Polymorphism was detected by digestion of PCR-amplified products with HindIII, HhaI and HaeIII restriction enzymes, followed by separation on 3% agarose gels, and resolved by ethidium bromide staining. Allele A of the κ-casein gene occurred at a higher frequency than allele B, in both Sahiwal and Tharparkar breeds. The genotypic frequencies of AA, AB, and BB in the Sahiwal and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Indian cattle; Κ-casein; Genetic polymorphism; PCR-RFLP.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000500015
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Caractérisation de marqueurs génétiques fonctionnels de la nutrition et/ou de l'adaptation (les amylases) chez l'huître creuse Crassostrea gigas : intérêts pour la sélection ArchiMer
Prudence, Marie.
Two amylase genes, A and B, from the oyster Crassostrea gigas were characterized. Using PCR-RFLP, 6 and 4 alleles, respectively, were described for the amylase genes A and B. The roles of A and B amylase genes were investigated experimentally. They are expressed during larval and adult stages, and A transcripts are more abundant than B. The A transcript increases significantly with temperature, in high trophic conditions. However, A and B transcript levels do not change when food quantity increases although amylase activity augments. The level of B is correlated with dietary starch quantities, whereas the amount of A appears to remain constant ; simultaneously amylase activity decreases and the KM increases. These results suggest that expression of B is...
Tipo: Text Palavras-chave: Enzymatic analyse; Genetic polymorphism; Genes; Nutrition; Growth; Environmental effects; Oysters; Amylases; Amylases; Analyse enzymatique; Polymorphisme génétique; Gènes; Nutrition; Croissance; Effets de l'environnement; Huîtres; Amylases; Amylases.
Ano: 2006 URL: http://archimer.ifremer.fr/doc/2006/these-1700.pdf
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Caracterização da diversidade genética de acessos do banco de germoplasma de seringueira. Repositório Alice
SOUZA, C. S. de.
A seringueira (Hevea brasiliensis) é uma planta popularmente conhecida por ser a principal fonte de borracha natural. Assim, é fundamental que este recurso genético esteja devidamente avaliado e caracterizado. O objetivo desse trabalho foi caracterizar por meio de marcadores microssatélites a diversidade genética de acessos do banco de germoplasma de seringueira da Embrapa Amazônia Ocidental, Embrapa Amazônia Oriental e Embrapa Cerrados. Foram amostrados 318 acessos, pertencentes às espécies Hevea brasiliensis, Hevea pauciflora, Hevea rigidifolia e híbridos interespecíficos. Foram testados 10 marcadores microssatélites. Os produtos amplificados foram genotipados em sequenciador automático. As estimativas genéticas estimadas foram: heterozigosidade esperada...
Tipo: Teses Palavras-chave: Marcador microssatélite; Ruber tree; Árbol de goma; Hevea pauciflora; Hevea rigidifolia; Fitomejoramiento; Variación genética; Marcadores genéticos; Repeticiones de microsatélite; Seringueira; Hevea Brasiliensis; Melhoramento Genético Vegetal; Variação Genética; Marcador Genético; Genótipo; Polimorfismo Genético; Plant breeding; Genetic variation; Genetic markers; Genotype; Genetic polymorphism; Microsatellite repeats.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1091127
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CCR5D32 mutation in three Brazilian populations of predominantly Sub-Saharan African ancestry Genet. Mol. Biol.
Carvalho,Mônica W.P.; Leboute,Ana P.M.; Oliveira,Silviene F.; Sousa,Sandra M.B.; Klautau-Guimarães,Maria de Nazaré; Simões,Aguinaldo L..
This study reports the frequencies of the CCR5D32 mutation of the beta-chemokine 5 gene and discusses the possible effects of past and recent gene flow in three quilombo remnants (Brazilians communities with anthropological African ancestry whose ancestors were escaped slaves): Rio das Rãs, Mocambo, and São Gonçalo in the northeastern region of Brazil. The CCR5D32 allele frequency of the Mocambo population was significantly higher (5.6%) than that found in the Rio das Rãs (1%) and São Gonçalo (0.9%) populations. These differences may reflect different proportions of parental populations in the founders individuals, a founder-effect and/or different histories of inter-ethnic contact. The frequency of the CCR5D32 allele in the Mocambo sample is similar to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CCR5; Genetic polymorphism; Sub-Saharan Afro-derived Brazilian populations; Ethnic-grouspecific marker.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000300002
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Combined association of Presenilin-1 and Apolipoprotein E polymorphisms with maternal meiosis II error in Down syndrome births Genet. Mol. Biol.
Bhaumik,Pranami; Ghosh,Priyanka; Ghosh,Sujay; Feingold,Eleanor; Ozbek,Umut; Sarkar,Biswanath; Dey,Subrata Kumar.
Abstract Alzheimer's disease and Down syndrome often exhibit close association and predictively share common genetic risk-factors. Presenilin-1 (PSEN-1) and Apolipoprotein E (APOE) genes are associated with early and late onset of Alzheimer's disease, respectively. Presenilin −1 is involved in faithful chromosomal segregation. A higher frequency of the APOE ε4 allele has been reported among young mothers giving birth to Down syndrome children. In this study, 170 Down syndrome patients, grouped according to maternal meiotic stage of nondisjunction and maternal age at conception, and their parents were genotyped for PSEN-1 intron-8 and APOE polymorphisms. The control group consisted of 186 mothers of karyotypically normal children. The frequencies of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chromosome; Genetic polymorphism; Karyotype; Meiosis; Microsatellite markers.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400577
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Distribution of N-acetyltransferase Type 1 (NAT1) genotypes and alleles in a Turkish population Genet. Mol. Biol.
Arslan,Serdal; Degerli,Naci; Bardakci,Fevzi.
NAT1 is an intronless gene on chromosome 8p21.3 encoding a 290-amino-acid-long protein showing acetyltransferase activity. Some 26 alleles of NAT1 gene have been identified in human populations. In the present study we determined the distributions of NAT1 genotypes and alleles in a sample of 201 individuals from the Turkish population in Central Anatolia. The most frequent genotypes were NAT1*4/NAT1*4 (51.74%), NAT1*10/NAT1*4 (22.39%), NAT1*11/NAT1*4 (7.46), NAT1*10/NAT1*10 (3.98%). Frequencies of NAT1*3, *4 (wild-type), *10 and *11 alleles were 3.73%, 69.6%, 17.66% and 7.2%, respectively. The frequency of NAT1*11 was the highest amongst the populations studied so far, the other allele frequencies being close to those described in Caucasian populations.
Tipo: Info:eu-repo/semantics/article Palavras-chave: NAT1 gene; Genetic polymorphism; Molecular epidemiology; Turkish population.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000200005
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Distribution of the CCR5delta32 allele (gene variant CCR5) in Rondônia, Western Amazonian region, Brazil Genet. Mol. Biol.
Farias,Josileide Duarte de; Santos,Marlene Guimarães; França,Andonai Krauze de; Delani,Daniel; Tada,Mauro Shugiro; Casseb,Almeida Andrade; Simões,Aguinaldo Luiz; Engracia,Vera.
Since around 1723, on the occasion of its initial colonization by Europeans, Rondonia has received successive waves of immigrants. This has been further swelled by individuals from northeastern Brazil, who began entering at the beginning of the twentieth century. The ethnic composition varies across the state according to the various sites of settlement of each wave of immigrants. We analyzed the frequency of the CCR5L32 allele of the CCR5 chemokine receptor, which is considered a Caucasian marker, in five sample sets from the population. Four were collected in Porto Velho, the state capital and the site of several waves of migration. Of these, two, from the Hospital de Base were comprised of HB Mothers and HB Newborns presenting allele frequencies of 3.5%...
Tipo: Info:eu-repo/semantics/article Palavras-chave: CCR5; CCR5Δ32; Rondônia; Genetic polymorphism; Allele frequency.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000100003
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Estrutura genética de Bertholletia excelsa ao longo da Amazônia brasileira. Repositório Alice
SILVA, L. L. de M. M.; COSTA, P. da; WADT, L. H. de O.; PAPPAS, M. de C. R.; CAMPOS, T. de; GUEDES, M. C.; SILVA, K. E. da; HOOGERHEIDE, E. S. S.; BALDONI, A. B.; SCOLES, R.; MARTORANO, L. G.; THOMAS, E.; KIMURA, R. K.; MARTINS, K..
A Bertholletia excelsaBonpl. (Lecythidaceae) é uma espécie arbórea endêmica das matas de terra firme e com ampla distribuição ao longo de toda a Floresta Amazônica. De grande relevância econômica devido à extração das sementes realizada por populações locais, está entre os produtos mais exportados da Amazônia. Atualmente, faz parte da lista oficial das espécies em extinção, sendo classificada como vulnerável. Tendo em vista este contexto torna-se de suma importância o estabelecimento de estratégias para definição de áreas prioritárias para a conservação da espécie. Uma dessas ferramentas é a caracterização da diversidade e estrutura genética em populações naturais. Esse trabalho amostrou árvores em 22 populações naturais da B. excelsa ao longo da Amazônia...
Tipo: Parte de livro Palavras-chave: Productos foretales no madereros; Espécie arbórea; Área de convservación; Castanha do Brasil; Diversidade genética; Madeira tropical; Nuez del brasil; Polimorfismo de nucleótido simple; Produto florestal não madeireiro (PFNM); PFNM; Variación genética.; Bertholletia Excelsa; Castanha do Para; Conservação; Essência Florestal; Lecythidaceae; População de Planta; Variação Genética.; Polimorfismo Genético; Single nucleotide polymorphism; Brazil nuts; Conservation areas; Genetic polymorphism; Genetic variation; Nontimber forest products; Tropical wood..
Ano: 2019 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1119847
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Genetic Analysis of Izoenzymes Polymorphisms in Silkworm (Bombyx mori L.) Strains - doi: 10.4025/actascibiolsci.v35i2.13102 Biological Sciences
Ronqui, Ludimilla; Fundação Universidade Federal de Rondônia; Fernandez, Maria Aparecida; Universidade Estadual de Maringá; Takasusuki, Maria Claudia Colla Ruvolo; Universidade Estadual de Maringá.
This work carried out to evaluates the polymorhism in the silkworm of different lineages using the isoenzymes electrophoresis to detect biochemical markers and to investigate the genetics of populations for those lineages. They were used as samples individual extracts of silk glands of second day old larvas of the fifth instar, originating from seven Japanese lineages and eight pure Chinese lineages maintained by the Cocamar-Cooperativa Agroindustrial de Maringá. The isozymes acid phosphatase (ACP), alkaline phosphatase (AKP) and carbonic anhydrase (CA) they were submitted to the electrophoresis in starch gels 14%. The esterases (EST) were analyzed in polyacrylamide gels to 10% and stained with α and b-naphtyl acetate. The total of 21 loci was detected,...
Palavras-chave: 2.02.04.00-0 silkworm; Genetic polymorphism; Isoenzymes Genética animal.
Ano: 2013 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/13102
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Genetic differentiation in natural populations of Lutzomyia longipalpis (Lutz &amp; Neiva) (Diptera: Psychodidae) with different phenotypic spot patterns on tergites in males Neotropical Entomology
Silva,MH; Nascimento,MDSB; Leonardo,FS; Rebêlo,JMM; Pereira,SRF.
Entomological surveys in the state of Maranhão have recorded morphologically distinct populations of Lutzomyia longipalpis (Lutz &amp; Neiva). Some populations have one pair of spots (1S) on the fourth tergite, while others have two pairs (2S) on the third and fourth tergites of males. In the present study we investigated the degree of genetic polymorphism among four populations in the municipalities of Caxias, Codó and Raposa, in the state of Maranhão, Brazil, by using RAPD (Random Amplified Polymorphic DNA) markers. A total of 35 loci were identified, of which 30 were polymorphic. The highest polymorphism was observed with primer OPA 4, which produced 11 different profiles. Genetic diversity was assessed using grouping methods that produced a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Abdominal spot; Genetic polymorphism; Leishmaniasis; RAPD-PCR; Sand fly.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-566X2011000400015
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