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Registros recuperados: 3
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Imprime registro no formato completo
Clinical and economic impact of generic versus brand name meropenem use in an intensive care unit in Colombia BJID
Ordóñez,Karen; Feinstein,Max M.; Reyes,Sergio; Hernández-Gómez,Cristhian; Pallares,Christian; Villegas,María V..
Abstract Background: Recent studies suggest that sustained use of generic antibiotics may be associated with clinical failure and emergence of antibacterial resistance. The present study was designed to determine the clinical outcome between the use of generic meropenem (GM) and brand-name meropenem (BNM). Additionally, this study evaluated the economic impact of GM and BNM to determine if the former represents a cost-effective alternative to the latter. Methods: Patients treated between January 2011 and May 2014 received GM while patients treated between June 2014 and March 2017 received BNM. Mortality was compared between groups. Total infection cost was defined by the cost of antimicrobial consumption, length of stay, and laboratory and imaging exams...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Generic drugs; Meropenem; Mortality; Costs; Critical care; Gram negative bacteria.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000400237
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Detection of multi drug resistant bacteria in major hospitals in Kano, North-West, Nigeria BJM
Yusuf,I.; Arzai,A.H.; Haruna,M.; Sharif,A.A.; Getso,M.I..
Two major hospitals in Kano, North West Nigeria have recorded increasing resistance of clinical pathogens to broad spectrum β lactams, mediated by extended spectrum β- lactamase (ESβL) and non ESBLs. A study was therefore undertaken to determine the occurrence and prevalence of plasmid and chromosomal mediated AmpC βL and carbapenemase in addition to already known ESBL due to increasing resistance of pathogens from the two hospitals to carbapenems, cephamycins and flouroquinolones. Antibiogram tests and ESBL, AmpC and carbapenemase production tests were performed on all the isolates. AmpC and carbapenemase producers were further screened for AmpC inducibility and metallo beta lactamase production respectively. Majority of the isolates (> 80%) were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: AmpC β-lactamases; Extended spectrum β-lactamases; Coexistence; Prevalence; Gram negative bacteria.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300005
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Imprime registro no formato completo
Estudio de la interferencia serológica en el diagnóstico de la brucelosis bovina en el modelo murino InVet
Díaz,A.G.; Soto,P.; Estein,S.M..
En Argentina, el control de la brucelosis bovina se apoya en la vacunación obligatoria de las terneras con la cepa 19 de Brucella abortus y en la eliminación de los animales seropositivos con destino a faena. Las pruebas serológicas que se emplean más frecuentemente son el BPA (Buffered Plate Antigen) (prueba tamiz) y el FPA (Fluorescence Polarization Assay) (prueba confirmatoria). Ambas detectan anticuerpos anti-cadena O del polisacárido inducidos por la vacunación o por la infección con brucelas de campo. En ocasiones se han encontrado, en un contexto de ausencia de enfermedad clínica, reacciones serológicas atípicas en bovinos adultos. Las mismas han sido atribuidas a la presencia de anticuerpos de reacción cruzada inducidos por vacunas que contienen...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Brucella abortus; Bacterias Gram negativas; Interferencia serológica; Gram negative bacteria; Serological crossreactivity.
Ano: 2012 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1668-34982012000100008
Registros recuperados: 3
Primeira ... 1 ... Última
 

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