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| Porfirio,Zenaldo; Ribeiro,Micheline P.; Estevam,Cicero S.; Houly,Ricardo L. S.; Sant'Ana,Antonio Euzébio G.. |
| Cyanobacteria (Microcystis aeruginosa), which produce powerful hepatotoxic cyclopeptides, were collected and submitted to the determination of toxicity through intraperitoneal injections made in 30 and 90 days-old Swiss albino mice. The liver and the spleen were histopathologically analyzed and the weight and vital signs development were monitored. Test of toxicity resulted in a LD50 of 154.28 mg.Kg-1. M. aeruginosa represented 95% of the analyzed biomass. The ratios between liver weight and body weight in the animal inoculated with a single dose were 6.0% and 7.2%, with multi doses 7.0% and 7.5% and in the control animals 4.0% and 5.0%, for adult and young animals, respectively. There was an accentuated increase in the volume and weight of the spleen, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Microcystis aeruginosa; Cyanobacteria; Hepatomegaly; Splenomegaly. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000300016 |
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| Vezozzo,Denise Cerqueira Paranaguá; Mendes-Correa,Maria Cassia; Cunha-Silva,Marlone; Alvarado-Mora,Mónica Viviana; França,João Ítalo Dias; Sebba,José Luiz; Nicodemo,Antonio Carlos; Oliveira,Claudia P.M.S.; Carrilho,Flair José. |
| OBJECTIVES: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients. This study aimed to compare ultrasound features and selected clinical and biochemical variables between patients with human immunodeficiency virus/hepatitis C virus co-infection (n = 16) versus hepatitis C virus mono-infection (n = 16). METHODS: Each patient underwent abdominal ultrasound, and a specific evaluation was performed in order to detect findings consistent with chronic liver disease. Characterization of spleen size, liver structural pattern, diameter of the portal, spleen, and mesenteric veins was based on classical ultrasound parameters. Propensity score... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ultrasonography; HIV/HCV co-infection; Hepatomegaly; Liver size; Cirrhosis. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200006 |
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