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| PERIPOLLI, E.; METZGER, J.; LEMOS, M. V. A. de; STAFUZZA, N. B.; KLUSKA, S.; OLIVIERI, B. F.; FEITOSA, F. L. B.; BERTON, M. P.; LOPES, F. B.; MUNARI, D. P.; LOBO, R. B.; MAGNABOSCO, C. de U.; DI CROCE, F.; OSTERSTOCK, J.; DENISE, S.; PEREIRA, A. S. C.; BALDI, F.. |
| Abstract Background The aim of this study was to assess genome-wide autozygosity in a Nellore cattle population and to characterize ROH patterns and autozygosity islands that may have occurred due to selection within its lineages. It attempts also to compare estimates of inbreeding calculated from ROH (FROH), genomic relationship matrix (FGRM), and pedigree-based coefficient (FPED). Results The average number of ROH per animal was 55.15 ± 13.01 with an average size of 3.24 Mb. The Nellore genome is composed mostly by a high number of shorter segments accounting for 78% of all ROH, although the proportion of the genome covered by them was relatively small. The genome autozygosity proportion indicates moderate to high inbreeding levels... |
| Tipo: Artigo de periódico |
Palavras-chave: Padroes ROH; Endogamia; Gado Nelore; Genoma; Genética Animal; Homozygosity. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1101339 |
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| REGITANO, L. C. de A.; VERARDO, L. L.; SILVA, F. F. e; MACHADO, M. A.; PANETTO, J. C. do C.; REIS, D. R. de L.; OTTO, P. I.; SILVA, M. V. G. B.; ZANELLA, R.; ALBUQUERQUE, M. do S. M.; EGITO, A. A. do; SILVA, L. O. C. da. |
| Cattle population history, breeding systems, and geographic subdivision may be reflected in runs of homozygosity (ROH), effective population size (Ne), and linkage disequilibrium (LD) patterns. Thus, the assessment of this information has become essential to the implementation of genomic selection on purebred and crossbred cattle breeding programs. In this way, we assessed the genotype of 19 cattle breeds raised in Brazil belonging to taurine, indicine, synthetic crossbreds, and Iberian-derived locally adapted ancestries to evaluate the overall LD decay patterns, Ne, ROH, and breed composition. We were able to obtain a general overview of the genomic architecture of cattle breeds currently raised in Brazil and other tropical countries. We found that, among... |
| Tipo: Artigo de periódico |
Palavras-chave: Rusticidade; Rusticity; Bovino; Gado; Genética Animal; Genoma; Produção Leiteira; Comportamento Animal; Fertilidade Animal; Homozygosity; Population size; Linkage disequilibrium; Milk production; Animal behavior; Animal fertility. |
| Ano: 2021 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1133730 |
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