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Diversity and uncommon HPV types in HIV seropositive and seronegative women attending an STI clinic BJM
Mattos,Adriana Tonani de; Freitas,Luciana Bueno de; Lima,Bettina Moulin Coelho; Miranda,Angélica Espinosa; Spano,Liliana Cruz.
Given the causal relationship between specific types of HPV with cervical cancer and precursor lesions, it is important to identify the viral type involved. The aim of this study is to access the prevalence of HPV types in HIV seropositive and seronegative women. Accordingly, 77 HPV positive cervical samples were obtained from 284 women (seropositive (n=112) and seronegative (n=172) for HIV) who attended a Sexually Transmitted Infection clinic, in Vitoria, Southeastern Brazil. Viral DNA was amplified by PCR using MY09/MY11 degenerated primers and the genotyping was performed by Restriction Fragment Length Polymorphism. Seventy five out of the 77 HPV samples were genotyped: 6, 11, 13, 16, 18, 26, 31, 31b, 32, 33, 34, 35, 52, 53, 55, 56, 58, 59, 61, 62, 64,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus (HPV); HIV seropositive and seronegative women; RFLP; Genotyping; Cervical secretion.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000200047
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Immune cellular response to HPV: current concepts BJID
Gonçalves,Maria Alice Guimarães; Donadi,Eduardo Antonio.
Although cellular immunity is essential for the elimination of human papillomavirus (HPV), the mechanisms involved are still poorly understood. We summarize the main mechanisms involved in cellular immune response to infections caused by HPV. Immunotherapies for HPV-related cancers require the disruption of T-cell response control mechanisms, associated with the stimulation of the Th1 cytokine response.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Human papillomavirus (HPV); Cervical intraepithelial neoplasia (CIN); Uterine cervical cancer; Cellular immune response; Cytokines.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000100001
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