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Abdoon,N. A.; Ali,A. A.; Alnema,A. A.; Hag-Ali,M.; Fatani,A. J.. |
The cumulative actions of scorpion neurotoxins are complex and may be traced to activation of different ion channels with subsequent release of various transmitters and modulators including inflammatory mediators. This could lead to various pathological manifestations such as acute respiratory distress syndrome (ARDS), systemic inflammatory response syndrome (SIRS), and multiple organ failure (MOF). Several approaches have been advocated to treat the multitude of scorpion-venom-elicited pathological changes. However, few have tried to combat the venom-induced effects on the inflammatory process, which manifest as ARDS, SIDS and MOF. Thus, the aim of this study was to determine the capability of inhibitors of different steps of the inflammatory sequence of... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leiurus quinquestriatus quinquestriatus; Scorpion venom; Acute respiratory distress syndrome; Systemic inflammatory response syndrome; Multiple organ failure; Montelukast; Hydrocortisone; Indomethacin. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000300003 |
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ROSA,MARIA INÊS DA; SOUZA,SUÉLI L.; FARIAS,BRUNA F. DE; PIRES,PATRÍCIA D.S.; DONDOSSOLA,EDUARDO R.; REIS,MARIA EDUARDA F. DOS. |
We performed a systematic review with the objective of verifying the efficacy of topical use 5% Acyclovir-1% Hydrocortisone cream compared to the placebo group for herpes simplex labialis treatment. We performed a literature search using MEDLINE, Embase, BIOSIS, LILACS, Scopus, Grey literature, the Cochrane Central Register of Controlled Trials, the ISI Web of Science and IBECS from 1990 to June 2014. We reported the outcomes using relative risk (RR) with 95% confidence intervals. The literature search yielded 180 potentially relevant publications. Reviews of the reference lists yielded two further citations. Among these papers, two were considered eligible for inclusion in this review. Both trials included 1,213 patients. A meta-analysis of these studies... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acyclovir; Herpes Labialis; Hydrocortisone; ME-609; Systematic Review. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301415 |
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Nogueira,Guilherme de Paula; Barnabe,Renato Campanarut; Bedran-de-Castro,João César; Moreira,Alankardison Ferreira; Fernandes,Wilson Roberto; Mirandola,Regina Mieko Sakata; Howard,Denise Louise. |
Exercise can be defined as "normal stress" stimulating body functions. Some reports suggest lactate as a stimulator of cortisol levels, while creatinine varies according to the amount of muscle tissue. In the present study we investigated the relationship between creatinine, serum lactate concentration and cortisol levels in training horses. Twenty-three Thoroughbred fillies were used, divided into 3 groups according to age and training protocol: G1, 1-2 years of age (N=7) on pasture, G2, 2-3 years (N=9) starting to be mounted, and G3, 3-4 years (N=7) racing at the Jockey Club. Blood samples were collected weekly during a six-month period at about 1:00 p.m. while the animals were resting. Cortisol was quantified with a commercial kit (Coat-a Count®) and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hydrocortisone; Horses; Lactates; Creatinine; Exercise. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962002000100010 |
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