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da Cunha,Marcelo Rodrigues; Laraia,Isabela Ortiz; Franco,Guacira R; Miguel,Natalia N; Maciel,Ana A; dos Santos,Geovane Ribeiro; Isayama,Ricardo Noboro. |
Bone metabolism is influenced by different factors and muscle activity acts as a stimulator of bone plasticity. Conditions such as nerve injuries can compromise bone physiology due to muscle inactivity. Preview studies have shown that nerve damage reduces P substance and calcitonin gene-related peptides, also known as neuropeptides that may have a key role on bone healing. Therefore, this study evaluated the osseointegration of hydroxyapatite implants in tibial defects of rats submitted to unilateral sciatic nerve section. Twelve Wistar rats were divided into two groups (G1 and G2). In G1, the sciatic nerve was left intact and in G2 the left sciatic nerve was completely sectioned. An experimental tibial bone defect was then created in both groups and... |
Tipo: Journal article |
Palavras-chave: Hydroxyapatite; Sciatic nerve; Bone healing. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200033 |
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FINISIE,MELLATIE R.; JOSUÉ,ATCHE; FÁVERE,VALFREDO T.; LARANJEIRA,MAURO C. M.. |
Bioceramic composites were obtained from chitosan and hydroxyapatite pastes synthesized at physiological temperature according to two different syntheses approaches. Usual analytical techniques (X-ray diffraction analysis, Fourier transformed infrared spectroscopy, Thermo gravimetric analysis, Scanning electron microscopy, X-ray dispersive energy analysis and Porosimetry) were employed to characterize the resulting material. The aim of this investigation was to study the bioceramic properties of the pastes with non-decaying behavior from chitosan-hydroxyapatite composites. Chitosan, which also forms a water-insoluble gel in the presence of calcium ions, and has been reported to have pharmacologically beneficial effects on osteoconductivity, was added to... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioceramic; Chitosan; Hydroxyapatite; Composites; Bone regeneration. |
Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000400006 |
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