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A broad-range PCR technique for the diagnosis of infective endocarditis BJM
Boujelben,Ines; Gdoura,Radhouane; Hammami,Adnane.
Abstract Infective endocarditis (IE) remains a severe and potentially fatal disease demanding sophisticated diagnostic strategies for detection of the causative microorganisms. The aim of the present study was to develop a broad-range 16S ribosomal RNA gene polymerase chain reaction in the routine diagnostic of IE for the early diagnosis of fatal disease. A broad-range PCR technique was selected and evaluated in terms of its efficiency in the diagnosis of endocarditis using 19 heart valves from patients undergoing cardiovascular surgeries at the Habib Bourguiba Hospital of Sfax, Tunisia, on the grounds of suspected IE. The results demonstrated the efficiency of this technique particularly in cases involving a limited number of bacteria since it helped to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Broad-range PCR; Infective endocarditis; Conventional methods; Negative culture; Phenotypic investigations.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300534
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Asymptomatic and symptomatic embolic events in infective endocarditis: associated factors and clinical impact BJID
Monteiro,Thaíssa S.; Correia,Marcelo G.; Golebiovski,Wilma F.; Barbosa,Giovanna Ianini F.; Weksler,Clara; Lamas,Cristiane C..
ABSTRACT Background: Embolic complications of infective endocarditis are common. The impact of asymptomatic embolism is uncertain. Objectives: To determine the frequency of emboli due to IE and to identify events associated with embolism. Methods: Retrospective analysis of an endocarditis database, prospectively implemented, with a post hoc study driven by analysis of data on embolic events. Data was obtained from the International Collaboration Endocarditis case report forms and additional information on embolic events and imaging reports were obtained from the medical records. Variables associated with embolism were analyzed by the statistical software R version 3.1.0. Results: In the study period, 2006-2011, 136 episodes of definite infective...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Infective endocarditis; Embolism; Asymptomatic embolism; Splenomegaly; Cardiac surgery; Splenectomy.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000300240
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Bartonella native valve endocarditis: the first brazilian case alive and well BJID
Lamas,C.; Favacho,A.; Ramos,R.G.; Santos,M.S.; Ferravoli,G.I.; Weksler,C.; Rozental,T.; Bóia,M.N.; Lemos,E.R.S..
Bartonella is an important cause of blood culture-negative endocarditis in recent studies. Seroprevalence studies in the States of Minas Gerais and Rio de Janeiro have shown Bartonella IgG positivity around 14% in healthy adults and 40% in HIV seropositive adults, respectively. A case report of a 46-year-old white male with moderate aortic regurgitation (AR) due to rheumatic heart disease (RHD), admitted due to worsening heart failure, is presented. Clinical features were apyrexia, anemia, polyclonal hypergammaglobulinemia, hematuria and splenomegaly. He was submitted to surgery due to worsening AR. Histopathology of the excised valve showed active bacterial endocarditis and underlying RHD. Routine blood cultures were negative. Indirect immunofluorescence...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bartonella spp.; Infective endocarditis; Blood culture-negative infective endocarditis; Rheumatic heart disease; Serology; Indirect immunofluorescence.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000600012
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First reported case of infective endocarditis caused by community-acquired methicillin-resistant Staphylococcus aureus not associated with healthcare contact in Brazil BJID
Fortes,Claudio Querido; Espanha,Claudia Adelino; Bustorff,Flavio Pedreira; Zappa,Bruno Cordeiro; Ferreira,Adriana Lucia Pires; Moreira,Regina Barbosa; Pereira,Nelson Gonçalves; Fowler Jr.,Vance G.; Deshmukh,Hitesh.
We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission and met modified Duke's criterion for infective endocarditis. The isolate was typed as Staphylococcal cassette chromosome (SCC) mec type IV and was positive for presence of Panton-Valentine leukocidin (PVL). Increased incidence of CA-MRSA endocarditis is a challenge for the internist to choose the best empirical therapy. Several authors have suggested an empirical therapy with both a beta-lactam and an anti-MRSA agent for serious S. aureus infections. Our patient...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Infective endocarditis; CA-MRSA; Brazil; PVL.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000600020
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Streptococcus bovis endocarditis: analysis of cases between 2005 and 2014 BJID
Mello,Renato; Santos,Marisa da Silva; Golebiosvki,Wilma; Weksler,Clara; Lamas,Cristiane.
Background: Streptococcus bovis is a classical etiology of endocarditis and is associated with colonic lesions. No series of cases from Brazil has been described. Objectives: To describe aspects of S. bovis endocarditis. Methods: This is a case series of patients admitted to a cardiac surgery referral center, during the years 2005-2014. Clinical, laboratory, echochardiographic, colonoscopic, treatment, surgical and outcome variables were studied. Results: Nine patients with S. bovis endocarditis were included; all cases fulfilled the modified Duke criteria. Incidence was 8/220 (4%) in years 2006-2014. There were seven male and two female patients; mean age was 56.7 years, standard deviation 13.4. All patients had native aortic valve involvement....
Tipo: Info:eu-repo/semantics/other Palavras-chave: Infective endocarditis; Streptococcus bovis group; Cardiac surgery; Colonic lesions.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200209
Registros recuperados: 5
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