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Acute inflammatory response in Nile tilapia fed probiotic Lactobacillus plantarum in the diet - doi: 10.4025/actascibiolsci.v33i3.8011 Biological Sciences
Dotta, Geovana; Laboratório AQUOS-Sanidade de Organismos Aquáticos, Depto. de Aqüicultura, CCA, UFSC - Rod. Admar Gozaga 1346 - 88040-900 - Florianópolis, SC - Brasil; Mouriño, José Luis Pedreira; Laboratório de Camarões Marinhos, Depto. de Aqüicultura, CCA, UFSC, Beco dos Coroas, Barra da Lagoa - Florianópolis, SC - Brasil; Jatobá, Adolfo; Laboratório de Camarões Marinhos, Depto. de Aqüicultura, CCA, UFSC, Beco dos Coroas, Barra da Lagoa - Florianópolis, SC - Brasil; Burgos Morán, Ricardo Ernesto; Universidad Politécnica de Catalunya, Campus del Baix Llobregat, Av. del Canal Olímpic, s/n - 08860 - Castelldefels, Catalunya - España; Pilati, Celso; UFSC; Martins, Maurício Laterça; UFSC.
The present study evaluated the acute inflammatory response induced by carrageenin (500 µg) injected in the swim bladder of Nile tilapia, after fed or not probiotic supplemented diet. Fifty four fish were distributed in six treatments and three replicates: Group A: Fish fed unsupplemented diet: 0.5 mL saline-injected fish; fish injected with 500 µg carrageenin diluted in 0.5 mL saline; Non-injected. Group B: Fish fed probiotic supplemented diet: saline-injected fish; carrageenin-injected fish; Non-injected. Fifteen days after feeding the fish were injected with carrageenin or saline. After six hours, inflammatory exudate was collected, as well as the blood for hematocrit, red blood cell (RBC) and white blood cell (WBC) counts,...
Tipo: Composição bioquímica Palavras-chave: 2.00.00.00-6 Ciencias Biologicas Tilapia; Probiotic; Lactobacillus plantarum; Inflammation; Haematology; Phagocytosis 2.00.00.00-6 Ciencias Biologicas Tilapia; Probiotic; Lactobacillus plantarum; Inflammation; Haematology; Phagocytosis.
Ano: 2011 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/8011
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Acute phase proteins in cats Ciência Rural
Rosa,Rita Mourão; Mestrinho,Lisa Alexandra Pereira.
ABSTRACT: Acute phase proteins (APP) are proteins synthesized and released largely by hepatocytes upon the occurrence of cell damage or invasion by microorganisms. This article reviews the use of APP in feline diseases, identifying their usefulness in the clinical setting, analyzing 55 published papers. Serum amyloid A, alpha-1 acid glycoprotein, and haptoglobin are the indicators pointed out by the authors as useful in monitoring the acute inflammatory response in cats. Although, APP measurement is still not routinely used in veterinary medicine, together with clinical signs and other blood parameters, was of clinical interest and applicability in diseases such as feline infectious peritonitis, pancreatitis, renal failure, retroviral and Calicivirus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Inflammation; Acute phase proteins; Cat..
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000400600
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ACUTE-PHASE REACTIONS, INCLUDING CYTOKINES, IN PATIENTS BITTEN BY BOTHROPS AND CROTALUS SNAKES IN BRAZIL J. Venom. Anim. Toxins
BARRAVIERA,B.; LOMONTE,B.; TARKOWSKI,A.; HANSON,L. Å.; MEIRA,D.A..
Thirty-one patients bitten by venomous snakes in Botucatu area (State of São Paulo - Brazil), sixteen by Bothrops spp. and fifteen by Crotalus durissus terrificus, were studied. The group comprised twenty-nine males and two females, ranging from fourteen to sixty-three years of age (mean 33 ± 15). Leukocytosis with neutrophilia and lymphopenia, increase of mucoproteins and C-reactive protein, decrease of total serum protein and albumin, were observed on the first day after the accident. In addition, increased serum levels of the cytokines IL-6 and IL-8, but not of IL-1<FONT FACE="Symbol">b</FONT> and TNF-<FONT FACE="Symbol">a</FONT>, were observed. The alterations were generally more intense in patients bitten by Crotalus durissus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Snake venom; Acute-phase reactions; Cytokines; C-reactive protein; Inflammation.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301995000100003
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Alternatively spliced MEFV transcript lacking exon 2 and its protein isoform pyrin-2d implies an epigenetic regulation of the gene in inflammatory cell culture models Genet. Mol. Biol.
Erdem,Gokce Celikyapi; Erdemir,Sule; Abaci,Irem; Aydin,Asli K. Kirectepe; Everest,Elif; Turanli,Eda Tahir.
Abstract The function of gene body DNA methylation in alternative splicing, and its relation to disease pathogenesis is not fully elucidated. The gene for familial Mediterranean fever (MEFV) encodes the pyrin protein and contains a 998 bp CpG island, covering the second exon, which is differentially methylated in FMF patients compared to healthy controls. Our further observation of increased exon 2-spliced MEFV transcript in leukocytes of FMF patients provoked us to test the role of exon methylation in alternative splicing using inflammatory cell culture models. First, in vitro exon methylation triggered an increased level of exon 2 exclusion using a splicing cassette in a promyelocytic leukemia cell line (HL-60). HL-60 cells subjected to methylating and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Exon methylation; MEFV; Pyrin; Alternative splicing; Inflammation.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400688
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An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress Anais da ABC (AABC)
Zacks,Michele A.; Wen,Jian-Jun; Vyatkina,Galina; Bhatia,Vandanajay; Garg,Nisha.
There is growing evidence to suggest that chagasic myocardia are exposed to sustained oxidative stress-induced injuries that may contribute to disease progression. Pathogen invasion- and replication-mediated cellular injuries and immune-mediated cytotoxic reactions are the common source of reactive oxygen species (ROS) in infectious etiologies. However, our understanding of the source and role of oxidative stress in chagasic cardiomyopathy (CCM) remains incomplete. In this review, we discuss the evidence for increased oxidative stress in chagasic disease, with emphasis on mitochondrial abnormalities, electron transport chain dysfunction and its role in sustaining oxidative stress in myocardium. We discuss the literature reporting the consequences of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chagasic cardiomyopathy; Reactive oxygen species; Inflammation; Mitochondria; Oxidant/antioxidant status; Oxidative damage.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652005000400009
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Aneurisma na artéria aorta em caprinos. Repositório Alice
SANTA ROSA, J.; BERNE, M. E. A.; JOHNSON, E. H..
Resumo: De 726 caprinos necropsiados, dois (0,28%) apresentaram aneurisma na arteria aorta, sendo um macho com idade de 48 meses e uma femea com cerca de 30 meses. Os animais eram oriundos de um rebanho mantido em regime semi-extensivo com pastejo em caatinga nativa e pernoite em aprisco. Macroscopicamente observou-se palidez das mucosas externas e das visceras. Nas cavidades toracica e abdominal estavam presentes grandes coagulos resultantes da ruptura das partes afetadas das arterias. As lesoes das arterias aorta toracica e abdominal foram carcterizadas pela dilatacao das paredes formando estruturas saculares com presenca de inumeros coagulos e tecidos necroticos de aproximadamente 10cm a 20cm de comprimento. Histologicamente, observou-se a destruicao do...
Tipo: Artigo de periódico Palavras-chave: Aneurisma; Arteria aorta; Ectasia; Aorta artery; Caprino; Doença vascular; Artéria; Inflamação; Goats; Goat diseases; Arteritis; Aneurysm; Vascular diseases; Animal diseases; Inflammation; Animal pathology.
Ano: 1989 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/514186
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Anti-inflammatory activity of Blutaparon portulacoides ethanolic extract against the inflammatory reaction induced by Bothrops jararacussu venom and isolated myotoxins BthTX-I and II J. Venom. Anim. Toxins incl. Trop. Dis.
Pereira,IC; Barbosa,AM; Salvador,MJ; Soares,AM; Ribeiro,W; Cogo,JC; Zamuner,SR.
This article reports the anti-inflammatory effect of Blutaparon portulacoides (B. portulacoides), specifically the ethanolic extract of its aerial parts, on the edema formation and leukocyte influx caused by Bothrops jararacussu (B. jararacussu) snake venom and Bothropstoxin-I and II (BthTX-I and II) isolated from this venom as an alternative treatment for Bothrops snakebites. The anti-inflammatory effect of B. portulacoides ethanolic extract was compared with an animal group pretreated with dexamethasone. B. portulacoides ethanolic extract significantly inhibited paw edema induced by B. jararacussu venom and by BthTX-I and II. Also, results demonstrated that the extract caused a reduction of the leukocyte influx induced by BthTX-I. However, the extract...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bothrops jararacussu; Myotoxins; Inflammation; Edema; Blutaparon portulacoides.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300013
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Anti-inflammatory activity of the apolar extract from the seaweed Galaxaura marginata (Rhodophyta, Nemaliales) J. Venom. Anim. Toxins incl. Trop. Dis.
Rozas,E.; Freitas,J. C..
The red seaweed Galaxaura marginata (Ellis &amp; Solander) Lamouroux, well known by the antibacterial activity of its polar extract and the cytotoxic activity of its oxygenated desmosterol, showed anti-inflammatory action in its apolar fraction. Topical anti-inflammatory activity was observed in samples collected at São Sebastião channel, northern littoral of São Paulo State, Brazil. The apolar extract and its fractions obtained through Thin-Layer Chromatography (TLC) reduced the topical inflammation produced by croton oil in mouse ear. Such data indicated that the apolar extract from the marine red alga G. marginata displayed anti-inflammatory activity (since 1mg/ear extract reduced 95±0.5% inflammation), which could be the result of the synergic...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Seaweed; Galaxaura marginata; Inflammation; Croton oil; Edema; Anti-inflammatory agents.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000200011
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Anti-inflammatory Effect of Silymarin on Ovarian Immunohistochemical Localization of TNF- Associated with Systemic Inflammation in Polycystic Ovarian Syndrome International Journal of Morphology
Kayedpoor,Parvin; Mohamadi,Shima; Karimzadeh-Bardei,Latifeh; Nabiuni,Mohammad.
Tumor necrosis factor alpha (TNF-a) and interleukin (IL)-6, are prominent mediators of inflammation and have been confirmed to be elevated in at least a subgroup of women with polycystic ovary syndrome (PCOS). In this study, the effects of Silymarin (SLM) on the expression TNF-a, IL-6, CRP and symptoms of PCOS were studied. In this research, PCOS was induced by injection of Estradiol Valerate. PCOS rats were divided into control and experimental groups received intraperitoneal injection SLM extract daily. After syndrome induction, ovaries were collected for histological and immunohistochemical evaluations. Serum IL-6 was detected by the ELISA kit. The results indicated the significant reduction in inflammatory markers and significant changes follicular...
Tipo: Journal article Palavras-chave: Immunohistochemistry; Inflammation; Silybum Marianum extract.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000200054
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Antinociceptive and anti-inflammatory effects of a Geissospermum vellosii stem bark fraction Anais da ABC (AABC)
LIMA,JOSÉLIA A.; COSTA,THIAGO W.R.; SILVA,LEANDRO L.; MIRANDA,ANA LUÍSA P.; PINTO,ANGELO C..
ABSTRACT Geissospermum vellosii (Pao pereira) is a Brazilian tree whose stem barks are rich in indole alkaloids that present intense anticholinesterase activity. The present study evaluated the effects of a stem bark fraction (PPAC fraction) and ethanolic extract (EE) of Pao pereira in classic murine models of inflammation and pain. The EE and PPAC fraction, both at a dose of 30 mg/kg, significantly reduced mice abdominal constriction induced by acetic acid by 34.8% and 47.5%, respectively. In the formalin test, EE (30 mg/kg) and PPAC fraction (30 and 60 mg/kg) inhibited only the second phase, by 82.8%, 84.9% and 100%, respectively. Compared with indomethacin, similar doses of EE or PPAC fraction were approximately twice as effective in causing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Geissospermum vellosii; Pao pereira; Antinociception; Inflammation; Cholinergic anti-inflammatory pathway.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100237
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Antioxidant, analgesic and anti-inflammatory effects of lavender essential oil Anais da ABC (AABC)
SILVA,GABRIELA L. DA; LUFT,CAROLINA; LUNARDELLI,ADROALDO; AMARAL,ROBSON H.; MELO,DENIZAR A. DA SILVA; DONADIO,MÁRCIO V.F.; NUNES,FERNANDA B.; AZAMBUJA,MARCOS S. DE; SANTANA,JOÃO C.; MORAES,CRISTINA M.B.; MELLO,RICARDO O.; CASSEL,EDUARDO; PEREIRA,MARCOS AURÉLIO DE ALMEIDA; OLIVEIRA,JARBAS R. DE.
Several studies have investigated the antinociceptive, immunomodulatory and anti-inflammatory properties of compounds found in the lavender essential oil (LEO), however to date, there is still lack of substantial data. The objective of this study was to assess the antioxidant, anti-inflammatory and antinociceptive effects of lavender essential oil. The 1,1-diphenyl-2-picrylhydrazyl radical decolorization assay was used for antioxidant activity evaluation. The anti-inflammatory activity was tested using two models of acute inflammation: carrageenan-induced pleurisy and croton oil-induced ear edema. The antinociceptive activity was tested using the pain model induced by formalin. LEO has antioxidant activity, which is dose-dependent response. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidants; Inflammation; Lavender; Nociception.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301397
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ANTITUMOR EFFECT OF SNAKE VENOMS J. Venom. Anim. Toxins
SILVA,R. J. DA; FECCHIO,D.; BARRAVIERA,B..
The search for biological antitumor agents has been pursued for over half a century. Snake venom has been shown to possess a wide spectrum of biological activities. The objectives of the present review are to evaluate the existing controversies on this subject published in a number of papers and to propose probable explanations for the phenomena observed. We reported our results obtained in a study, in which we evaluated the action of the venoms of Crotalus durissus terrificus and Bothrops jararaca on Ehrlich ascites tumor cells. We noticed an important antitumor effect, mainly with Bothrops jararaca venom, as well as an increase in the functional activity of macrophages. We also observed an increase in the number of mononuclear and polymorphonuclear cells...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Inflammation; Venom; Snakes; Crotalus durissus terrificus; Bothrops jararaca.
Ano: 1996 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301996000200002
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Assessment of Anti-inflammatory and Antioxidant Properties of Safranal on CCI4-Induced Oxidative Stress and Inflammation in Rats Anais da ABC (AABC)
ALAYUNT,ÖMER N.; AKSOY,LAÇINE; KARAFAKIOĞLU,YASEMIN S.; SEVIMLI,SEVCAN.
Abstract: The present study aimed to determine the antioxidative and anti-inflammatory effects of safranal on damage induced by CCl4. Experimental animals were divided into five groups. The first group was determined as the control group and no treatment was conducted. Second group rats were administered 1 mL/kg-day CCI4 during the experiment. Rats in Groups 3, 4 and 5 were administered 1 mL/kg-day CCI4 and 25 mg/kg, 50 mg/kg; 100 mg/kg safranal, respectively via gavage. Oxidative-antioxidant parameters, liver function enzymes and inflammatory cytokine levels were determined in liver samples obtained from the rats. Data analysis demonstrated that oxidative stress and inflammation markers were significantly higher in CCI4 administered groups (p<0.05)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant; CCI4; Inflammation; Safranal.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300704
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Association between soluble biomarkers - microbial translocation, inflammation and cardiovascular risk in HIV- infected individuals: a systematic review BJPS
Borato,Danielle Cristyane Kalva; Vellosa,José Carlos Rebuglio.
Microbial translocation is associated with the increased risk of cardiovascular disease in HIV-infected individuals. There is scarce information regarding the possible associations between the biomarkers of microbial translocation, inflammation and cardiovascular risk that can be evaluated in clinical laboratories using plasma or serum samples. This systematic review was conducted according to the PRISMA protocol in order to verify the most used soluble biomarkers of microbial translocation, inflammation and cardiovascular risk, as well as possible associations between them, in HIV-infected individuals. A search was performed using the Medline, Scopus and Web of Science databases to identify existing studies regarding the relationship between microbial...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Microbial translocation; Inflammation; Cardiovascular risk; HIV; Biomarkers.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100614
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Association of IL-6 and CRP gene polymorphisms with obesity and metabolic disorders in children and adolescents Anais da ABC (AABC)
Todendi,Pâmela F.; Klinger,Elisa I.; Ferreira,Michele B.; Reuter,Cézane P.; Burgos,Miria S.; Possuelo,Lia G.; Valim,Andréia R.M..
Activation of adipose tissue inflammation is associated with obesity caused by lipid accumulation in adipocytes. Through this activation, proinflammatory cytokines, such as Interleukin-6 (IL-6) and C-reactive protein (CRP) seem to influence metabolic disorders. The present study evaluated whether polymorphisms in the CRP (rs1205) and IL-6 (rs1800795, rs2069845) genes are associated with the development of metabolic disorders in children and adolescents. A cross-sectional study was performed, consisting of 470 students from the municipality of Santa Cruz do Sul, Brazil, aged 7-17 years. Body mass index (BMI) was classified according to overweight and obesity. Genotyping was performed by real-time Polymerase Chain Reaction(PCR). Anthropometric...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Inflammation; Obesity; Polymorphisms; Risk; Schoolchildren.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000200915
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Avian cytokines in health and disease Rev. Bras. Ciênc. Avic.
Wigley,P; Kaiser,P.
Cytokines are proteins secreted by cells that play an important role in the activation and regulation of other cells and tissues during inflammation and immune responses. Although well described in several mammalian species, the role of cytokines and other related proteins is poorly understood in avian species. Recent advances in avian genetics and immunology have begun to allow the exploration of cytokines in health and disease. Cytokines may be classified in a number of ways, but may be conveniently arranged into four broad groups on the basis of their function. Proinflammatory cytokines such as interleukin-6 and interleukin-1beta play a role in mediating inflammation during disease or injury. Th1 cytokines, including interleukin-12 and interferon-gamma,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cytokines; Immunity; Infectious disease; Inflammation; Vaccination.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2003000100001
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B-1 cell: the precursor of a novel mononuclear phagocyte with immuno-regulatory properties Anais da ABC (AABC)
Lopes,José Daniel; Mariano,Mario.
Characterization of the origin, properties, functions and fate of cells is a fundamental task for the understanding of physiological and pathological phenomena. Despite the bulk of knowledge concerning the diverse characteristics of mammalian cells, some of them, such as B-1 cells, are still poorly understood. Here we report the results obtained in our laboratory on these cells in the last 10 years. After showing that B-1 cells could be cultured and amplified in vitro, a series of experiments were performed with these cells. They showed that B1 cells reside mostly in the peritoneal and pleural cavities, migrate to distant inflammatory foci, coalesce to form giant cells and participate in granuloma formation, both in vitro and in vivo. They are also able to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: B-1 cells; IL-10; Inflammation; Infection; Neoplasia; BALB/Xid mice.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300013
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Candesartan inhibits inflammation through an angiotensin II type 1 receptor independent way in human embryonic kidney epithelial cells Anais da ABC (AABC)
YU,YING; JIANG,HAIFENG; NIU,YANGYANG; ZHANG,XIAOQIN; ZHANG,YINGYING; LIU,XI; QI,TAO; YU,CHEN.
Abstract: Besides stimulating vasoconstriction, Angiotensin II is also well known in inducing reactive oxygen species and promoting inflammatory phenotype switch via its type 1 receptor. In clinic, Angiotensin II type 1 (AT1) receptor blocker like candesartan has been widely applied as an antihypertensive medication. We previous have demonstrated that a higher dose of candesartan plays a protective role after kidney injury. However, whether candesartan could exhibit anti-inflammatory effects remains unclear. Here, by stimulating isolated human embryonic kidney epithelial cells with tumor necrosis factor-α (TNF-α), we observed the anti-inflammation capacity of candesartan ex vivo. It was found that pre-treat with candesartan significantly suppressed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin II type 1 receptor blockers; Candesartan; Inflammation; Reactive oxygen species.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300701
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Clinacanthus nutans: Its potential against diabetic vascular diseases BJPS
Azemi,Ahmad Khusairi; Mokhtar,Siti Safiah; Rasool,Aida Hanum Ghulam.
Diabetes is an independent risk factor for the development of cardiovascular disease, with approximately 80% of cardiovascular mortality and morbidity linked to vascular complications such as atherosclerosis. It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and/or alternative medicine. One plant that has received attention from diabetic patients for its perceived antidiabetic properties is Clinacanthus nutans, a member of the Acanthaceae family that is known as snake grass. Ethnomedical applications of this herb have been identified for the treatment of certain conditions, including fever, diabetes, skin rashes, and insect bites. This review aims to assess the potential of C. nutans to be used in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: C. nutans; Diabetes; Inflammation; Cardiovascular disease.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100635
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Consequences of gestational diabetes to the brain and behavior of the offspring Anais da ABC (AABC)
SOUSA,RICARDO A.L. DE; TORRES,YASMIN S.; FIGUEIREDO,CLAUDIA P.; PASSOS,GISELLE F.; CLARKE,JULIA R..
ABSTRACT Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during the second/third trimesters of pregnancy in previously normoglycemic women. It is currently estimated that 10% of all pregnancies in the United States show this condition. For many years, the transient nature of GD has led researchers and physicians to assume that long-term consequences were absent. However, GD diagnosis leads to a six-fold increase in the risk of developing type 2 diabetes (T2D) in women and incidence of obesity and T2D is also higher among their infants. Recent and concerning evidences point to detrimental effects of GD on the behavior and cognition of the offspring, which often persist until adolescence or adulthood. Considering that the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Insulin resistance; Hippocampus; Inflammation; Depression; Learning; Memory; Programing.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000502279
Registros recuperados: 68
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