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Evaluation of the clinical and cardiorespiratory effects of propofol microemulsion in dogs Ciência Rural
Corrêa,André Luís; Tamanho,Renato Batista; Moraes,Aury Nunes de; Beier,Suzane Lilian; Regalin,Doughlas; Farias,Felipe Hertzing; Spolti,Pâmela; Oleskovicz,Nilson.
This research aimed to evaluate the clinical and cardiorespiratory effects of a propofol formulation with nanometer droplet diameter in dogs. Six adult healthy female dogs weighing 14.8±1.2kg were used in this study. Each dog received two treatments with a 15-day washout period. A microemulsion (MICRO) or lipid emulsion (EMU) of propofol was administered intravenously (IV) for induction and maintenance of anesthesia. Anesthesia was maintained with a constant rate infusion of propofol (0.4mg kg-1 minute-1). Cardiorespiratory variables were recorded before induction (baseline), immediately after and at 15-minute intervals for 90 minutes after treatment. Arterial blood samples were also taken for blood gas analysis, except at 45 and 75 minutes after...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propofol; Microemulsion; Lipid emulsion; Cardiorespiratory; Dogs.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000600026
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