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A FRET analysis to unravel the role of cholesterol in Rac1 and PI 3-kinase activation in the InlB/Met signalling pathway Inra
Seveau, S.; Tham, T. N.; Payrastre, B.; Hoppe, A. D.; Swanson, J. A.; Cossart, P..
The signalling pathway for the hepatocyte growth factor receptor, Met/HGF-R, is hijacked by the bacterial surface protein InlB to induce Listeria monocytogenes entry into non-phagocytic cells. We previously showed that Listeria invades host cells by interacting with specialized microdomains of the host plasma membrane called lipid rafts. In this study, we analysed in living cells signalling events that are crucial for Listeria entry using a fluorescence resonance energy transfer-based microscopic method. Phosphoinositide (PI) 3-kinase activity and Rac1 signalling induced by Listeria interacting with epithelial cells were monitored as well as signalling induced by soluble InlB and the Met natural ligand HGF. We found that InlB and HGF induced...
Tipo: Journal Article Palavras-chave: PROTEINE MICROBIENNE; LISTERIA MONOCYTOGENES; BACTERIE PATHOGENE; MALADIE INFECTIEUSE; CELLULE EPITHELIALE; INTERNALINE InlB; RECEPTEUR; FACTEUR DE CROISSANCE; SIGNAL; ENZYME; CHOLESTEROL; PHOSPHOINOSITIDE KINASE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200993335bc&uri=/notices/prodinra1/2009/09/
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A survey of the incidence of Nosema disease (Nosema apis Zander) of the honey bee in south Australia National Institute of Agronomic Research
Doull, Keith; Cellier, K.M..
A 2-year survey of the incidence cf nosema disease of the honey bee in South Australia bas shown that a spring peak of infection may be expected each year. The level of infection is at a minimum in midsummer and winter but a rise may occur in the autumn. It was considered that the disease, either in the form of a few infected bees or of spores on the combs, was present in all hives throughout the survey. Significant differences in the level of infection between hives in the same apiary suggested that there may be factors, varying in some way from hive to hive, which determine the level of infection within each hive. In view of the appreciable variation between hives it is evident that the incidence of the disease in individual hives was estimated with...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; AUSTRALIA; NOSEMA APIS; INFECTIOUS DISEASE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; AUSTRALIE; NOSEMA APIS; MALADIE INFECTIEUSE.
Ano: 1961 URL: http://hdl.handle.net/2174/479
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A theory of the causes of development of epizootics of nosema disease of the honey bee National Institute of Agronomic Research
Doull, Keith M..
A hypothesis is presented to explain the developments of epizootics of nosema disease of the honey bee, Apis mellifera Linnaeus. It is assumed that most hives contain some lightly infected carrier bees in which the numbers of the parasite increase very slowly. But under the influence of certain conditions the parasites within these bees increase in numbers very quickly, and, if other conditions are favorable, an epizootic of the disease will develop. A hypothetical course of development of an epizootic is described. It is suggested that the numbers of the parasite increase when the metabolism of infected bees is changed so as to change the environment of the intracellular parasites. Changes in the metabolism of infected bees are considered to be stress...
Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; NOSEMA; INFECTIOUS DISEASE; EPIZOOTICS; ABEILLE DOMESTIQUE; INSECTE SOCIAL; NOSEMA; MICROSPORIDIE; MALADIE INFECTIEUSE; EPIDEMIE.
Ano: 1961 URL: http://hdl.handle.net/2174/478
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Ætiology of european foul brood ; a disease of the larval honey-bee National Institute of Agronomic Research
Bailey, L..
THE cause of European foul brood was originally thought to be Bacillus alvei or a mixture of B. alvei and Streptococcus apis. The causative organism was later named and described by White as Bacillus pluton, a lanceolate Gram-positive bacterium. This organism is the first of several which have been found to appear in diseased larvæ. However, White and others failed to culture B. pluton in vitro and it was afterwards considered to be a dissociant form of Bacillus alvei, of Bacterium eurydice, or of both. Others have maintained that B. pluton is a separate organism. It has been pointed out that Streptococcus pluton would be a more suitable designation than Bacillus pluton both on morphological grounds and in the absence of evidence that it forms spores. For...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; LARVAE; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; ETIOLOGY; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LARVE; LOQUE EUROPEENNE; MALADIE INFECTIEUSE; ETIOLOGIE.
Ano: 1956 URL: http://hdl.handle.net/2174/497
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Amoeba disease in the queen honeybee National Institute of Agronomic Research
Örösi-Pal, Z..
Queen honeybee have hitherto been found resistant to Malpighamoeba mellificae. For example 516 queens were examined by the author in1954-61, and none was infected. He has now found amoeba cysts in 3 out of 7 dead queens wintered in cages with attendant workers (instead of in a colony). Reasons for this difference between queens free in colonies and caged in incubators are discussed.
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; QUEEN; AMOEBIASIS; INFECTION; DISEASE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; REINE; AMOEBA; MALADIE INFECTIEUSE.
Ano: 1963 URL: http://hdl.handle.net/2174/400
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Anopheles gambiae PRS1 modulates plasmodium development at both midgut and salivary gland steps Inra
Chertemps, T.; Mitri, C.; Perrot, S.; Sautereau, J.; Jacques, J.-C.; Thiery, I.; Bourgouin, C.; Rosinski-Chupin, I..
Background: Invasion of the mosquito salivary glands by Plasmodium is a critical step for malaria transmission. From a SAGE analysis, we previously identified several genes whose expression in salivary glands was regulated coincident with sporozoite invasion of salivary glands. To get insights into the consequences of these salivary gland responses, here we have studied one of the genes, PRS1 (Plasmodium responsive salivary 1), whose expression was upregulated in infected glands, using immunolocalization and functional inactivation approaches. Methodology/Principal Findings: PRS1 belongs to a novel insect superfamily of genes encoding proteins with DM9 repeat motifs of uncharacterized function. We show that PRS1 is induced in response to Plasmodium, not...
Tipo: Journal Article Palavras-chave: PLASMODIUM; MOUSTIQUE; GLANDE SALIVAIRE; SALIVE; MALADIE INFECTIEUSE; PROTEINE; TRANSMISSION DE LA MALADIE; VECTEUR DE LA MALADIE; INTERACTION MOLECULAIRE; RT-PCR; SDS-PAGE; ARTHROPODA; HEXAPODA; EXPRESSION DES GENES; MICROSCOPIE CONFOCALE; INSECTE; PARASITOSE MALARIA PARASITE; MOLECULAR-INTERACTIONS; BERGHEI SPOROZOITES; MOSQUITO; INVASION; INFECTION; PROTEIN; VECTOR; CELLS; FALCIPARUM.
Ano: 2010 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2010f5c08798&uri=/notices/prodinra1/2010/11/
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European foul brood : a disease of the larval honeybee (Apis mellifera L.) caused by a combination of streptococcus pluton (Bacillus pluton White) and Bacterium eurydice White National Institute of Agronomic Research
Bailey, L..
Result of preliminary experiments have shown that European foul brood disease of the larval honeybee can be caused in bee colonies by spraying their brood with suspensions of Streptococcus pluton (Bacillus pluton White) and Bacterium eurydice White if the two organisms are grown together in mixed anaerobic culture ; fifth subcultures of a mixed culture were usually virulent, although virulence diminished rapidly after further sub-cultivation. It was not possible to cause the disease by simultaneous inoculation with separate cultures of the two organisms. As there is a tendency for colonies of S. pluton and B. eurydice to grow within, or upon, each other on agar in anaerobic cultures, the separate cultures of each organism were subcultured five times to try...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; LARVAE; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; STREPTOCOCCUS PLUTON; BACTERIUM EURYDICE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LARVE; LOQUE EUROPEENNE; MALADIE INFECTIEUSE; STREPTOCOCCUS PLUTON; BACTERIUM EURYDICE.
Ano: 1957 URL: http://hdl.handle.net/2174/495
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Importance of terrestrial vertebrates in the Chikungunya epidemic on La Réunion Island (Indian Ocean) Inra
Vourc'h, G.; Halos, L.; Pascal, M.; Le Berre, M.; Duval, T.; Aumont, G.; Bremont-Deletang, M..
Tipo: Meeting Paper Palavras-chave: MOUSTIQUE; CHIKUNGUNYA; SEROPREVALENCE; MALADIE VIRALE; SEROLOGIE; MALADIE INFECTIEUSE; VIRUS; HUMAIN; ANIMAL DOMESTIQUE; ANIMAL SAUVAGE; EPIDEMIE TOGAVIRIDAE; AEDES AEGYPTI; AEDES ALBOPICTUS.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200726e9c946&uri=/notices/prodinra1/2008/01/
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Infectious diseases of the honeybee National Institute of Agronomic Research
Bailey, L..
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; INFECTIOUS DISEASE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; MALADIE INFECTIEUSE.
Ano: 1959 URL: http://hdl.handle.net/2174/496
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Sexist diseases IRD
Garenne, Michel; Lafon, M..
Tipo: Text Palavras-chave: MORTALITE; TAUX DE MORTALITE; SEX RATIO; FEMME; INFECTION; AGENT PATHOGENE; VIRUS; IMMUNITE; HORMONE; SEXE; DONNEES STATISTIQUES; GROUPE D'AGE; CAUSE DE DECES; MALADIE INFECTIEUSE; TUBERCULOSE.
Ano: 1998 URL: http://www.documentation.ird.fr/hor/fdi:010035434
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Small noncoding RNAs controlling pathogenesis Inra
Toledo-Arana, A.; Cossart, P..
Infectious diseases are a leading cause of mortality worldwide. A major challenge in achieving their eradication is a better understanding of bacterial pathogenesis processes. The recent discovery of small noncoding RNAs (sRNAs) as modulators of gene expression in response to environmental cues has brought a new insight into bacterial regulation. sRNAs coordinate complex networks of stress adaptation and virulence gene expression. sRNAs generally ensure such a regulation by pairing to mRNAs of effector and/or regulatory genes, or by binding to proteins. An updated view on bacterial models responsible for important infections illustrates the key role of sRNAs in the control of pathogenesis.
Tipo: Journal Article Palavras-chave: MALADIE INFECTIEUSE; BACTERIE PATHOGENE; ARNS; GENE; FACTEUR DE VIRULENCE; PATHOGENESE; BACTERIE PATHOGENE; EXPRESSION DES GENES; REGULATION; ADAPTATION AU STRESS; VIRULENCE.
Ano: 2007 URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2009d5b2a802&uri=/notices/prodinra1/2010/11/
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The cause of european foul brood National Institute of Agronomic Research
Bailey, L..
Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LOQUE EUROPEENNE; MALADIE INFECTIEUSE.
Ano: 1957 URL: http://hdl.handle.net/2174/491
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The control of nosema disease National Institute of Agronomic Research
Bailey, L..
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; NOSEMA; MICROSPORIDIA; INFECTIOUS DISEASE; CONTROL; ABEILLE DOMESTIQUE; INSECTE SOCIAL; NOSEMA; MICROSPORIDIE; MALADIE INFECTIEUSE; LUTTE.
Ano: 1954 URL: http://hdl.handle.net/2174/494
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The epizootiology of european foulbrood of the larval honey bee, Apis mellifera Linnaeus National Institute of Agronomic Research
Bailey, L..
Larvae, artificially infected when 0 to 1 day old with Streptococcus pluton (White) and placed in colonies, were usually ejected by adult bees. Ejection was delayed from colonies deprived either of unsealed brood or their queen, or which were reinforced with adult bees. The feces of surviving larvae whose weight was subnormal, contained many viable cells of S. pluton. Colonies reinforced with unsealed brood removed more infected larvae than usual. It is concluded that infected larvae are ejected when larval food is merely adequate, as it may be when a colony is growing rapidly ; and they are kept when larval food is more abundant, as it may be when brood rearing is retarded. Natural outbreaks of disease occurred when brood-rearing, in colonies heavily...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; LARVAE; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LARVE; LOQUE EUROPEENNE; MALADIE INFECTIEUSE.
Ano: 1960 URL: http://hdl.handle.net/2174/493
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The gross and histological pathology of a hairless-black syndrome in the adult honey bee, Apis mellifera National Institute of Agronomic Research
Horvath, Roberta J.; Rothenbuhler, Walter C..
Twenty diseased and 17 control bees were studied grossly and histologically with respect to pathological manifestations of an adult bee disease (tentatively called hairless-black syndrome), which has not been clearly distinguished in the literature from several other diseases of adult bees. In a diseased bee as compared with a control, the abdomen was abnormally distended by an accumulation of unusually aqueous feces; the midgut was often white and translucent instead of brown; the lumen of the small intestinal portion of the hindgut contained an increased amount of basophilic material, probably intestinal flora; the wall of the small intestine had large lesions and necrotic appearing areas in about half of the cases; the cytoplasm of the small intestinal...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; ADULT; INFECTIOUS DISEASE; HISTOLOGY; HAIRLESS-BLACK SYNDROME; VIRUS; CHRONIC BEE PARALYSIS; ABEILLE DOMESTIQUE; INSECTE SOCIAL; ADULTE; MALADIE INFECTIEUSE; HISTOLOGIE; VIRUS; PARALYSIE CHRONIQUE.
Ano: 1972 URL: http://hdl.handle.net/2174/344
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The gross and histological pathology of a hairless-black syndrome in the adult honey bee, Apis mellifera National Institute of Agronomic Research
Horvath, Roberta J.; Rothenbuhler, Walter C..
Twenty diseased and 17 control bees were studied grossly and histologically with respect to pathological manifestations of an adult bee disease (tentatively called hairless-black syndrome), which has not been clearly distinguished in the literature from several other diseases of adult bees. In a diseased bee as compared with a control, the abdomen was abnormally distended by an accumulation of unusually aqueous feces; the midgut was often white and translucent instead of brown; the lumen of the small intestinal portion of the hindgut contained an increased amount of basophilic material, probably intestinal flora; the wall of the small intestine had large lesions and necrotic appearing areas in about half of the cases; the cytoplasm of the small intestinal...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; ADULT; INFECTIOUS DISEASE; HISTOLOGY; HAIRLESS-BLACK SYNDROME; VIRUS; CHRONIC BEE PARALYSIS; ABEILLE DOMESTIQUE; INSECTE SOCIAL; ADULTE; MALADIE INFECTIEUSE; HISTOLOGIE; VIRUS; PARALYSIE CHRONIQUE.
Ano: 1972 URL: http://hdl.handle.net/2174/344
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The isolation and cultural characteristics of streptococcus pluton and further observations on bacterium eurydice National Institute of Agronomic Research
Bailey, L..
An account is given of the development of a reliable method for the isolation of Streptococcus pluton (Bacillus pluton White), an organism associated with European foul-brood disease of the larval honeybee. S. pluton, isolated as an anaerobe, may be trained to grow as an aerobe in rod form. Its principal anaerobic growth requirements are a low molar ratio of Na: K, high inorganic phosphate concentration, glucose or fructose, and undetermined factors provided by yeast extract. Peptones are harmful to growth. Aerobic growth has no very critical requirements other than glucose, fructose or sucrose. Bacterium eurydice White which, together with S. pluton, causes European foul-brood disease grows well anaerobically on a yeast extract + glucose + fructose...
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; LARVAE; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; STREPTOCOCCUS PLUTON; BACTERIUM EURYDICE; ISOLATION; CULTURE; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LARVE; LOQUE EUROPEENNE; MALADIE INFECTIEUSE; STREPTOCOCCUS PLUTON; BACTERIUM EURYDICE; ISOLATION; CULTURE.
Ano: 1957 URL: http://hdl.handle.net/2174/500
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The natural mechanism of suppression of Nosema apis Zander in enzootically infected colonies of the honey bee, Apis mellifera Linnaeus National Institute of Agronomic Research
Bailey, L..
Honey bees, artificially infected with Nosema apis Zander and introduced into an enzootically infected colony in summer when infection was naturally diminishing, were all infected and developed similar numbers of spores to those in naturally infected bees in spring when infection was high. This, and other evidence, suggests infection is not naturally suppressed by increased environmental temperature, but by reduction of infective fecal matter of the bees, which do not transmit infection to young individuals in summer.
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; NOSEMA APIS; MICROSPORIDIA; INFECTIOUS DISEASE; NATURAL SUPPRESSION; ABEILLE DOMESTIQUE; INSECTE SOCIAL; NOSEMA APIS; MICROSPORIDIE; MALADIE INFECTIEUSE; SUPPRESSION NATURELLE.
Ano: 1959 URL: http://hdl.handle.net/2174/492
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The pathogenicity for honey-bee larvae of microorganisms associated with european foulbrood National Institute of Agronomic Research
Bailey, L..
Tests made on larvae in normal bee colonies with pure cultures of Streptococcus pluton (White), Streptococcus faecalis Andrews and Horder, and Bacillus alvei Cheshire and Cheyne, three bacterial species commonly associated with European foulbrood (EFB), showed that S. pluton was the natural prirnary etiological agent. These results, together with other recent work, indicate that S. pluton is the cause of EFB throughout the world. Of the other associated bacterial species, Bacterium eurydice White, which is the most commnon, and S. faecalis probably have supplementary pathogenic effects. Bacillus alvei and other less common bacilli are saprophytes of the dead larvae.
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; LARVAE; EUROPEAN FOULBROOD; INFECTIOUS DISEASE; MICROORGANISM; BACTERIA; SAPROPHYTE; STREPTOCOCCUS PLUTON; STREPTOCOCCUS FAECALIS; BACILLUS ALVEI; BACTERIUM EURIDYCE; PATHOGENICITY; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LARVE; MALADIE NOIRE; PARALYSIE CHRONIQUE; MALADIE INFECTIEUSE; MICROORGANISME; BACTERIE; SAPROPHYTE; STREPTOCOCCUS PLUTON; STREPTOCOCCUS FAECALIS; BACILLUS ALVEI; BACTERIUM EURIDYCE; PATHOGENICITE; LOQUE EUROPEENNE.
Ano: 1963 URL: http://hdl.handle.net/2174/370
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Torulopsis apicola nov. spec., new isolates from bees National Institute of Agronomic Research
Hajsig, M..
When examining the normal fungal flora in the intestinal tract of bees, we isolated 7 strains of one yeast species from 6 out of 8 beehives. From each hive 10 bees were examined. These strains belonged to the genus Torulopsis, as given by Lodder and Kreger-van Rij (1952), but not to any known species. We are therefore describing a new species, for which we propose the name Torulopsis apicola. The description of this new budding yeast is based on the standard methods used by Lodder and Kreger-Van Rij (1952) and by Wickerham (1951) for the identification of yeasts.
Tipo: Journal Article-postprint Palavras-chave: HONEYBEE; APIS MELLIFERA; APIDAE; HYMENOPTERA; SOCIAL INSECT; YEAST; FUNGUS; INTESTINAL FLORA; MICROBIOLOGY; INFESTIOUS DISEASE; NEW SPECIES; ABEILLE DOMESTIQUE; INSECTE SOCIAL; LEVURE; FLORE INTESTINALE; MICROBIOLOGIE; MALADIE INFECTIEUSE; DETERMINATION; ESPECE NOUVELLE.
Ano: 1958 URL: http://hdl.handle.net/2174/341
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