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| Registros recuperados: 22 | |
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| Montenegro,G; Salas,F; Peña,RC; Pizarro,R. |
| En mieles monoflorales de la especie chilena Quillaja saponaria se detectaron los compuestos fenólicos: ácido cumárico y ácido salicílico, la flavona naringenina y el flavonol kaempferol, utilizando cromatografía líquida de alta resolución. Estos extractos mostraron actividad antibacteriana contra Pseudomonas aureginosa, Escherichia coli, Staphylococcus typhi, S. aureus, Streptococcus pneumoniae tipo β, y Vibrio cholerae, y actividad antifúngica contra la levadura Candida albicans. En el extracto etanólico, adicionalmente, se identificaron algunos compuestos del aroma y de descomposición. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Miel; MIC; Quillaja saponaria; Manuka; Flavonas; Ácidos fenólicos; Compuestos fenólicos. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572009000200010 |
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| Morales Cabrera, Mercedes. |
| En este estudio se evaluó la actividad antimicrobiana de los extractos etanólicos, metanólicos y acuosos (frío y caliente) de cálices deshidratados de Hibiscus sabdariffa L. de cinco genotipos, sobre S. typhimurium (ATCC14028) y S. cholleraesuis (ATCC10708), se empleó el método difusión en agar. Se determinó la concentración mínima inhibitoria (CMI) y la concentración mínima bactericida (CMB) por dilución. Se analizó la influencia del pH en la actividad antimicrobiana. Así mismo se realizó la caracterización fenólica de los extractos etanólicos. El efecto antimicrobiano fue variable; los extractos de la variedad Alma blanca (cálices verdes), presentaron el mayor efecto antimicrobiano (diámetros de inhibición de12.5 a 19.5 mm) sobre ambos serotipos de... |
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Palavras-chave: CMI; CMB; PH; Salmonella; Compuestos fenólicos; HPLC; MIC; MCB; Phenolic compounds; Fitopatología; Maestría. |
| Ano: 2011 |
URL: http://hdl.handle.net/10521/568 |
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| Morales Cabrera, Mercedes. |
| En este estudio se evaluó la actividad antimicrobiana de los extractos etanólicos, metanólicos y acuosos (frío y caliente) de cálices deshidratados de Hibiscus sabdariffa L. de cinco genotipos, sobre S. typhimurium (ATCC14028) y S. cholleraesuis (ATCC10708), se empleó el método difusión en agar. Se determinó la concentración mínima inhibitoria (CMI) y la concentración mínima bactericida (CMB) por dilución. Se analizó la influencia del pH en la actividad antimicrobiana. Así mismo se realizó la caracterización fenólica de los extractos etanólicos. El efecto antimicrobiano fue variable; los extractos de la variedad Alma blanca (cálices verdes), presentaron el mayor efecto antimicrobiano (diámetros de inhibición de12.5 a 19.5 mm) sobre ambos serotipos de... |
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Palavras-chave: CMI; CMB; PH; Salmonella; Compuestos fenólicos; HPLC; MIC; MCB; Phenolic compounds; Fitopatología; Maestría. |
| Ano: 2011 |
URL: http://hdl.handle.net/10521/568 |
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| Ferreira,Peracio Rafael Bueno; Mendes,Cíntia Sorandra Oliveira; Rodrigues,Cínthia Gracielly; Rocha,Juliane Caroline Moura; Royo,Vanessa de Andrade; Valério,Henrique Maia; Oliveira,Dario Alves de. |
| In vitro tests conducted with extracts rich in tannins have identified several biological activities of this class of substance. Thus, this paper intends to evaluate the antibacterial activity of tannin-rich fraction obtained from leaf extracts of Anacardium humile A.St.-Hil. Extracts of A. humile leaves in 70% acetone were semi-purified with ethyl acetate and butanol. We quantified the total tannins of the semi-purified fractions, of the crude extract and of aqueous residues and then performed tests of the antibacterial activity of the tannins against Staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa ATCC 27853 and Enterococcus faecalis ATCC 29212. All positive extracts underwent tannin isolation using a Sephadex LH-20 column. The tannins isolated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phenolic; Cajuí; Antibacterial; MIC; MBC; Sephadex LH-20. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782012001000023 |
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| Souza,Jeana M.E.; Chang,Marilene R.; Brito,Daniela Z.; Farias,Katyuce S.; Damasceno-Junior,Geraldo A.; Turatti,Izabel C.C.; Lopes,Norberto P.; Santos,Edson A.; Carollo,Carlos A.. |
| Abstract We evaluated the antimicrobial activity of Aspilia latissima - an abundant plant from the Brazilian Pantanal region - against Candida albicans, Candida parapsilosis, Candida krusei, Candida tropicalis, Pseudomonas aeruginosa, Enterococcus faecalis, Escherichia coli and Staphylococcus aureus. The crude extracts and fractions showed activity in all tested microorganisms. The chloroform fraction of the leaves and roots showed the most antimicrobial activity against S. aureus, with an MIC of 500 μg/mL. This fraction was submitted to bioautographic assays to characterize the activity of the compounds. Two bands from the leaves (L-A and L-B) and three bands from the roots (R-C, R-D and R-E) were bioactive. Within the root-derived bands, the terpene... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aspilia latissima; Staphylococcus aureus; Bioautographic; MIC; Terpenes. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000401103 |
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| Li,Liang-Mei; Li,Jun; Zhang,Xiu-Ying. |
| Background: The antimicrobial properties and molecular interaction analysis of curcumin and its derivatives against three different strains of Streptococcus pneumoniae (Penicillin-susceptible, Penicillin-intermediate and Penicillin-resistant) are studied. Results: These properties were analyzed based on the measurement of the inhibition zone, minimum inhibitory concentration (MIC), and rate of kill revealed that curcumin monoglucoside, curcumin diglucoside and curcumin possessed strong antimicrobial properties even on the Penicillin-resistant strains. Additionally, the molecular docking simulation analyses against Penicillin Binding Protein of S. pneumoniae also confirm that these compounds docked at the active site of the enzyme. Further, the molecular... |
| Tipo: Journal article |
Palavras-chave: Antimicrobial; Curcumin; MIC; Molecular docking; Penicillin-resistant. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582016000100002 |
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| Kalia,S.B.; Kaushal,G.; Kumar,M.; Cameotra,S.S.; Sharma,A.; Verma,M.L.; Kanwar,S.S.. |
| A few mixed ligand transition metal carbodithioate complexes of the general formula [M(4-MPipzcdt)x(phen)y]Y (M = Mn(II), Co(II), Zn(II); 4-MPipzcdt = 4-methylpiperazine-1-carbodithioate; phen = 1,10-phenanthroline; x = 1 and y = 2 when Y = Cl; x = 2 and y = 1 when Y = nil) were synthesized and screened for their antimicrobial activity against Candida albicans, Escherichia coli, Pseudomonas aeruginosa,Staphylococcus aureus andEnterococcusfaecalis by disk diffusion method. All the complexes exhibited prominent antimicrobial activity against tested pathogenic strains with the MIC values in the range <8-512 μgmL-1. The complexes [Mn(4-MPipzcdt)2(phen)] and [Co(4-MPipzcdt)(phen)2]Cl inhibited the growth of Candida albicans at a concentration as low as 8... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial; Metal ions; 4-methylpiperazine-1-carbodithioate; MIC; Zone of inhibition. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000400024 |
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| AKINPELU,DA; ADEGBOYE,MF; ADELOYE,OA; OKOH,AI. |
| The in vitro antibacterial activity of crude methanolic extract of the seeds of Garcinia kola was investigated. The extracts exhibited antibacterial activities with zones of inhibition ranging from 10 mm to 25 mm. The minimum inhibitory concentration of the diethyl ether fraction was between 0.313 and 5.0 mg/ml, while that of butanol fraction varied from 0.157 to 5.0 mg/ml. The butanol fraction killed about 77% of Bacillus anthracis and 79% of Escherichia coli cells within 120 min at a concentration of 5.0 mg/ml. Protein leakage from the B. anthracis and E. coli cells when exposed to the butanol and diethyl ether fractions was observed. We conclude that Garcinia kola seed extract has a broad spectrum antibacterial activity, with the butanol and diethyl... |
| Tipo: Journal article |
Palavras-chave: Garcinia kola; Antimicrobial activity; MIC; Killing rate; Protein leakage. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300005 |
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| MONTENEGRO,GLORIA; PORTALUPPI,MARIANA C; SALAS,FRANCISCO A; DÍAZ,MARÍA F. |
| An ethanol extract prepared from the gametophyte Chilean native moss Sphagnum magellanicum was dried out, weighed and dissolved in distilled water. This extract was then assayed for its antibacterial activity against the G(-) bacteria Azotobacter vinelandii, Erwinia carotovora subsp. carotovora, Enterobacter aerogenes, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholerae, and the G(+) bacteria Staphylococcus aureus subsp. aureus, and Streptococcus type b. The growth of the cultures of E. carotovora subsp. carotovora, and V. cholerae was inhibited at a concentration of 581mg/ml of extract, while the cultures of E. coli, S. typhi and Streptococcus type b were inhibited at a concentration of 1.16 mg/mL of extract. The concentration of... |
| Tipo: Journal article |
Palavras-chave: Sphagnum magellanicum; Phenolic compounds; Antibacterial activity; MIC. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000200012 |
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| Pereira Júnior,Delton José; Figueiredo,Henrique César Pereira; Carneiro,Daniela Oliveira; Leal,Carlos Augusto Gomes. |
| Objetivou-se com este trabalho determinar a concentração inibitória mínima (MIC) de oxitetraciclina para isolados de Aeromonas hydrophila obtidos de pescado, água de cultivo de peixes e casos de septicemia hemorrágica em peixes. Foi determinado MIC de 100 isolados de A. hydrophila, oriundos de 12 pisciculturas localizadas nos Estados de Minas Gerais, Rio de Janeiro e Rio Grande do Sul, utilizando a técnica de macrodiluição em caldo. Os resultados demonstraram que 14 isolados apresentaram MIC>100 µg/mL (resistentes) e 86 apresentaram MIC<12,5 µg/mL (sensíveis). Não houve diferença entre os isolados de pescado, caso clínico e água de cultivo. Conclui-se que a variação demonstrada pode representar um risco de seleção de linhagens bacterianas resistentes... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Aeromonas hydrophila; Oxitetraciclina; Resistência a antibióticos; MIC; Brasil. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542006000600023 |
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| Severino,Vanessa Gisele Pasqualotto; Silva,Maria Fátima das Graças Fernandes da; Lucarini,Rodrigo; Montanari,Lilian Bueno; Cunha,Wilson Roberto; Vinholis,Adriana Helena Chicharo; Martins,Carlos Henrique Gomes. |
| Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hortia oreadica; Rutaceae; Antibacterial activity; MIC; Oral pathogens. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000300015 |
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| Jasuja,Nakuleshwar Dut; Gupta,Deepak Kumar; Reza,Mohtashim; Joshi,Suresh C.. |
| In the present study, rapid reduction and stabilization of Ag+ ions with different NaOH molar concentration (0.5 mM, 1.0 mM and 1.5 mM) has been carried out in the aqueous solution of silver nitrate by the bio waste peel extract of P.granatum. Generally, chemical methods used for the synthesis of AgNPs are quite toxic, flammable and have adverse effect in medical application but green synthesis is a better option due to eco-friendliness, non-toxicity and safe for human. Stable AgNPs were synthesized by treating 90 mL aqueous solution of 2 mM AgNO3 with the 5 mL plant peels extract (0.4% w/v) at different NaOH concentration (5 mL). The synthesized AgNPs were characterized by UV-Vis spectroscopy, TEM and SEM. Further, antimicrobial activities of AgNPs were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Silver nanoparticles; Biowaste; Antibacterial activity; MIC; SEM; TEM. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400024 |
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| Singariya,Premlata; Kumar,Padma; Mourya,Krishan Kumar. |
| The present study was carried out to determine the possible bioactive components (steroids) of Cenchrus setigerus using GC-MS analysis and in vivo estimation of metabolites (total soluble sugar, soluble protein, proline and total phenolics), photosynthetic pigments (chlorophyll-a, chlorophyll-b and carotenoids) of seedlings and antimicrobial activity of extracts in various polar solvents from the leaves of C. setigerus. Antimicrobial activity was evaluated against three Gram-negative bacteria, including Proteusmirabilis, Klebsiella pneumonia and Agrobacterium tumefaciens andone fungus Aspergillus niger using 'disc diffusion' method, followed by the determination of minimum inhibitory concentrations (MIC) by broth dilution method. Results revealed the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cenchrus grass; Photosynthetic pigments; Total soluble sugar; Proline; Antibacterial activity; MIC; MBC/MFC. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132014000100010 |
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| Rahman,Atiqur; Siddiqui,Shah Alam; Oke-Altuntas,Feyza; OKAY,Sezer; GÜL,Fatih; Demirtas,Ibrahim. |
| Abstract Lasia spinosa (L.) Thwaites is a widely used ethnomedicinal plant in Bangladesh. In this study, we investigated phenolic contents, volatile compounds and fatty acids, and essential oil components of extracts prepared from aerial parts of the plant. The main volatile compounds were methyl ester of oleic acid, palmitic acid and stearic acid as determined by GC/MS. Phenolic contents of the extracts were determined qualitatively and quantitatively by HPLC/TOF-MS. Six phenolic compounds (syringic acid, morin, gentistic acid, 4-hydroxybenzoic acid, cinnamic acid, and apigenin) were found in the extracts. GC/MS analysis of steam distilled essential oil showed camphor, α-pinene and δ-3-carene as the main constituents. In DPPH radical scavenging assay, the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: GC/MS; HPLC/TOF-MS; DPPH radical scavenging activity; Metal chelating; MIC. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100405 |
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| Asif,Mohammad; Singh,Anita; Khan,Shah Alam; Husain,Asif. |
| We report herein the synthesis and pharmacological evaluation of a new series of 6-aryl-2-(imidazol-1-yl/1,2,4-triazol-1-yl)-2-methyl-4,5-dihydro-(2H)-pyridazin-3-one (3a-j) as potential anticonvulsant and antitubercular agents. The title compounds were prepared by reacting 6-aryl-4,5-dihydro-(2H)-pyridazin-3-one (2a-e) with formaldehyde and secondary cyclic amine imidazole or 1,2,4-triazole as per Mannich reaction. Anticonvulsant activity of pyridazinone derivatives was tested at 50 mg.kg-1 dose level against maximal electroshock (MES), isoniazid (INH, 250 mg.kg-1) and pentylenetetrazole (PTZ at 80 mg.kg-1) induced seizure methods. Phenytoin sodium (25 mg.kg-1) and sodium valproate (100 mg.kg-1) were used as reference drugs for comparison purpose.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Evaluation; Anticonvulsant; Antitubercular; MIC. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300601 |
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| Oliva-Neto,Pedro de; Yokoya,Fumio. |
| The antimicrobial effect of several products including commercial formulations currently used in sugar and alcohol factories was determined by adapted MIC (Minimal Inhibitory Concentration) test on Saccharomyces cerevisiae and on natural contaminants Lactobacillus fermentum and Leuconostoc mesenteroides. The MIC test by macrodilution broth method was adapted by formulating of the culture medium with cane juice closely simulating industrial alcoholic fermentation must. Acid penicillin V (MIC 0.10-0.20 µg/ml) and clindamycin (MIC 0.05-0.40 µg/ml) were most effective against bacterial growth in 24 h. Among the chemicals, sulphite (MIC 10-40 µg/ml), nitrite (MIC <117 µg/ml) and copper sulphate (75-300 µg/ml) were the most effective. Zinc and manganese... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial compound; MIC; S. cerevisiae; Lactic acid bacteria. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822001000100003 |
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| Registros recuperados: 22 | |
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