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| Almeida,J.R.C.; Alves,T.C.T.F.; Wajngarten,M.; Rays,J.; Castro,C.C.; Cordeiro,Q.; Telles,R.M.S.; Fraguas,R.J.; Busatto,G.F.. |
| The relevance of the relationship between cardiac disease and depressive symptoms is well established. White matter hyperintensity, a bright signal area in the brain on T2-weighted magnetic resonance imaging scans, has been separately associated with cardiovascular risk factors, cardiac disease and late-life depression. However, no study has directly investigated the association between heart failure, major depressive symptoms and the presence of hyperintensities. Using a visual assessment scale, we have investigated the frequency and severity of white matter hyperintensities identified by magnetic resonance imaging in eight patients with late-life depression and heart failure, ten patients with heart failure without depression, and fourteen healthy... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Major depressive disorder; Old age; Magnetic resonance imaging; Cardiac failure; Cerebrovascular disease; Cardiovascular risk factors. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300014 |
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| Wen,X.J.; Wang,L.M.; Liu,Z.L.; Huang,A.; Liu,Y.Y.; Hu,J.Y.. |
| We assessed the efficacy and tolerability of the augmentation of antidepressants (ATDs) with atypical antipsychotics (AAPs) to treat patients with major depressive disorder. A retrograde study to identify relevant patient data included databases of PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and Database of Abstracts of Reviews of Effects. Data from 17 trials, involving 3807 participants, were identified. The remission rate (RR) and overall response rate (ORR) of adjunctive treatment with AAPs were significantly higher than placebo treatment: RR=1.90 (95%CI=1.61-2.23, z=7.74, P<0.00001) and ORR=1.68 (95%CI=1.45-1.94, z=7.07, P<0.00001). We found that the short-term (4 weeks) treatment [ORR=1.70 (95%CI=0.98-2.95, Z=1.89, P=0.06)]... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Atypical antipsychotics; Major depressive disorder; Adjunctive therapy; Meta-analysis. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700605 |
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| Xu,Y.; Bai,S.J.; Lan,X.H.; Qin,B.; Huang,T.; Xie,P.. |
| New generation antidepressant therapies, including serotonin-norepinephrine reuptake inhibitor (SNRIs), were introduced in the late 1980s; however, few comprehensive studies have compared the benefits and risks of various contemporary treatments for major depressive disorder (MDD) in young patients. A comprehensive literature search of PubMed, Cochrane, Embase, Web of Science, and PsycINFO databases was conducted from 1970 to January 2015. Only clinical trials that randomly assigned one SNRI or placebo to patients aged 7 to 18 years who met the diagnostic criteria for major depressive disorder were included. Treatment success, dropout rate, and suicidal ideation/attempt outcomes were measured. Primary efficacy was determined by pooling the risk ratios... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adolescent; Child; Major depressive disorder; Meta-analysis; Randomized controlled trial; Serotonin and norepinephrine reuptake inhibitor. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600704 |
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| Valiengo,L.C.L.; Benseñor,I.M.; Lotufo,P.A.; Fraguas Jr,R.; Brunoni,A.R.. |
| Patients with clinical diseases often present psychiatric conditions whose pharmacological treatment is hampered due to hazardous interactions with the clinical treatment and/or disease. This is particularly relevant for major depressive disorder, the most common psychiatric disorder in the general hospital. In this context, nonpharmacological interventions could be useful therapies; and, among those, noninvasive brain stimulation (NIBS) might be an interesting option. The main methods of NIBS are repetitive transcranial magnetic stimulation (rTMS), which was recently approved as a nonresearch treatment for some psychiatric conditions, and transcranial direct current stimulation (tDCS), a technique that is currently limited to research scenarios but has... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neuromodulation; Liaison; Major depressive disorder; Transcranial stimulation. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000815 |
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