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Alterations in proteins of bone marrow extracellular matrix in undernourished mice BJMBR
Vituri,C.L.; Alvarez-Silva,M.; Trentin,A.G.; Borelli,P..
The objective of the present study was to determine the effect of protein malnutrition on the glycoprotein content of bone marrow extracellular matrix (ECM). Two-month-old male Swiss mice were submitted to protein malnutrition with a low-protein diet containing 4% casein as compared to 20% casein in the control diet. When the experimental group had attained a 20% loss of their original body weight, we extracted the ECM proteins from bone marrow with PBS buffer, and analyzed ECM samples by SDS-PAGE (7.5%) and ECL Western blotting. Quantitative differences were observed between control and experimental groups. Bone marrow ECM from undernourished mice had greater amounts of extractable fibronectin (1.6-fold increase) and laminin (4.8-fold increase) when...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fibronectin; Bone marrow; Extracellular matrix; Malnutrition.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000800004
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Anthropometric midarm measurements can detect systemic fat-free mass depletion in patients with chronic obstructive pulmonary disease BJMBR
Sanchez,F.F.; Faganello,M.M.; Tanni,S.E.; Lucheta,P.A.; Pelegrino,N.G.; Hasegawa,S.H.; Ribeiro,S.M.; Godoy,I..
Our objective was to determine whether anthropometric measurements of the midarm (MA) could identify subjects with whole body fat-free mass (FFM) depletion. Fifty-five patients (31% females; age: 64.6 ± 9.3 years) with mild/very severe chronic obstructive pulmonary disease (COPD), 18 smokers without COPD (39% females; age: 49.0 ± 7.3 years) and 23 never smoked controls (57% females; age: 48.2 ± 9.6 years) were evaluated. Spirometry, muscle strength and MA circumference were measured. MA muscle area was estimated by anthropometry and MA cross-sectional area by computerized tomography (CT) scan. Bioelectrical impedance was used as the reference method for FFM. MA circumference and MA muscle area correlated with FFM and biceps and triceps strength. Receiver...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fat-free mass depletion; Midarm anthropometry; Chronic obstructive pulmonary disease; Malnutrition; Nutritional status assessment.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500011
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ApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children. Repositório Alice
ORIÁ, R. B.; PATRICK, P. D.; ORIÁ, M. O. B.; LORNTZ, B.; THOMPSON, M. R.; AZEVEDO, O. G. R.; LOBO, R. N. B.; PINKERTON, R. F.; GUERRANT, R. L.; LIMA, A. A. M..
A series of studies have shown that the heavy burdens of diarrheal diseases in the first 2 formative years of life in children living in urban shanty towns have negative effects on physical and cognitive development lasting into later childhood. We have shown that APOE4 is relatively common in shanty town children living in Brazil (13.4%) and suggest that APOE4 has a protective role in cognitive development as well as weight-for-height in children with heavy burdens of diarrhea in early childhood (64/123; 52%), despite being a marker for cognitive decline with Alzheimer?s and cardiovascular diseases later in life. APOE2 frequency was higher among children with heaviest diarrhea burdens during the first 2 years of life, as detected by PCR using the...
Tipo: Artigo de periódico Palavras-chave: Apolipoprotein E; Malnutrition; Diarrhea; Children.
Ano: 2010 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/857019
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ApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children BJMBR
Oriá,R.B.; Patrick,P.D.; Oriá,M.O.B.; Lorntz,B.; Thompson,M.R.; Azevedo,O.G.R.; Lobo,R.N.B.; Pinkerton,R.F.; Guerrant,R.L.; Lima,A.A.M..
A series of studies have shown that the heavy burdens of diarrheal diseases in the first 2 formative years of life in children living in urban shanty towns have negative effects on physical and cognitive development lasting into later childhood. We have shown that APOE4 is relatively common in shanty town children living in Brazil (13.4%) and suggest that APOE4 has a protective role in cognitive development as well as weight-for-height in children with heavy burdens of diarrhea in early childhood (64/123; 52%), despite being a marker for cognitive decline with Alzheimer’s and cardiovascular diseases later in life. APOE2 frequency was higher among children with heaviest diarrhea burdens during the first 2 years of life, as detected by PCR using the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Apolipoprotein E; Malnutrition; Diarrhea; Children.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300005
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Atrophy of the Nitrergic Myenteric Neurons in the Descending Colon Rats Submitted to Protein and Vitamin Deficiency International Journal of Morphology
Araújo,Eduardo José de Almeida; Hermes,Catchia; Miranda Neto,Marcílio Hubner de; Almeida,Elton Carlos de; Sant'Ana,Débora de Mello Gonçales.
Effects of protein and B-complex vitamin deficiency were assessed with respect to the morphometry of myenteric neurons in the descending colon of adult rats. Sixteen animals were divided into two groups: Control Group (CG, n=8) and Experimental Group (EG, n=8). The CG received 22% protein chow and the EG received 4% protein chow for 120 days. The descending colon was submitted to NADH- and NADPH-diaphorase technique in order to evidence nervous cells in the whole mounts preparations. In the EG, NADH-d positive neurons presented reduced nuclei, while NADPH-d positive neurons showed atrophy of the soma area (~41.7%) inducing an increase of the proportion occupied by the nucleus inside in the soma of these cells.
Tipo: Journal article Palavras-chave: Malnutrition; Large intestine; Enteric nervous system; Myenteric plexus; Neural plasticity.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300047
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Batata Doce de Polpa Cor Alaranjada - Parcerias Prometedoras para Assegurar a Integração dos Aspectos Nutricionais na Investigação e Extensão Agrícola AgEcon
Low, Jan W.; Uaiene, Rafael N.; Andrade, Maria Isabel; Howard, Julie A..
Resultados das Investigações do Departamento de Análise de Políticas MADER-Direcção de Economía
Tipo: Report Palavras-chave: Food security; Food policy; Mozambique; Sweet potato; Malnutrition; Crop Production/Industries; Food Consumption/Nutrition/Food Safety; Q18.
Ano: 2000 URL: http://purl.umn.edu/55216
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Can calories from ethanol contribute to body weight preservation by malnourished rats? BJMBR
Aguiar,A.S.; Da-Silva,V.A.; Boaventura,G.T..
Our objective was to compare the use of calories from ethanol by well-nourished and malnourished rats in terms of body weight. Female Wistar rats weighing 170-180 g at the beginning of the study were used. The animals were divided into two groups (N = 12 each): group W received water ad libitum and group E an ethanol solution ad libitum as the only source of liquid throughout the experiment. The concentration of ethanol was increased weekly from 0 to 5, 10, 20 and 40% (v/v). In the well-nourished phase (A), all rats received food ad libitum (AW and AE). Ethanol treatment (AE) was then interrupted and water was offered to both groups. After 2 weeks both AW and AE rats were submitted to food restriction (50% of group AW food consumption), thus initiating the...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Ethanol; Weight gain; Malnutrition; Rats; Toxicity.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000600009
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Characterization of the myenteric neuronal population and subpopulation of the duodenum of adult wistar rat fed with hypoproteic chow Anais da ABC (AABC)
Sant'Ana,Débora M.G.; Araújo,Eduardo J.A.; Ramos,Diego H.; Hermes-Uliana,Catchia; Natali,Maria Raquel M..
The effects of severe protein malnutrition (4%) on myenteric neurons of Wistar rat duodenum, in relation to a standard 22%-protein diet for rodents, were assessed in this study. Segments of the duodenum from 10 rats from each nutritional group were submitted to the elaboration of whole mounts - 5 stained with Giemsa to determine the total population of myenteric neurons and the others stained by a histochemical method to detect nervous cells through the NADPH-diaphorase enzyme activity for studying the subpopulation of nitrergic neurons. The area of 100 neurons per animal, totalizing 2,000 neurons, were randomly measured by using the Image Pro-Plus®software. Malnourished rats presented 34.38% lower body weight and 10.60% duodenum length reduction when...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Enteric nervous system; Malnutrition; Myenteric plexus; Nitrergic neurons.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000300022
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DNA damage in BALB/c mice infected with Lacazia loboi and its relation to nutritional status J. Venom. Anim. Toxins incl. Trop. Dis.
Barbosa,Adriana Sierra Assencio Almeida; Oliveira,Larissa Ragozo Cardoso de; Tavares,Francilene Capel; Lima,Carlos Roberto Gonçalves de; Diório,Suzana Madeira; Calvi,Sueli Aparecida; Vilani-Moreno,Fátima Regina; Pereira,Paulo Câmara Marques.
AbstractBackground Jorge Lobo’s disease, also known as lacaziosis, is a cutaneous-subcutaneous mycosis with chronic evolution. It is caused by the fungus Lacazia loboi. Herein we report a study that relates the genotoxicity caused by L. loboi in isogenic mice with nutritional status, through a normal or restricted diet.Methods DNA damage was assessed in the peripheral blood by the comet assay (tail intensity).Results The results for leukocytes showed increases in the mean tail intensity in mice under dietary restriction, in infected mice under dietary restriction and in infected mice ingesting a normal diet.Conclusion These results indicate that dietary restriction and L. loboi infection may increase DNA damage levels in mice, as detected by the comet assay.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Jorge Lobo’ disease; Lacazia loboi; Malnutrition; Mice; Genotoxicity; Comet assay.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100317
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Emerging Challenges for Food and Nutrition Policy in Developing Countries AgEcon
Stamoulis, Kostas G.; Pingali, Prabhu L.; Shetty, Prakash.
As the income and the average caloric intake of developing country populations increase, a relative shift in diets is taking place. The general pattern of change can be described as a shift towards more 'westernized' diets and away from traditional ones. Accompanying this dietary trend are the substantial and rapid changes in food production, retailing and distribution systems. After reviewing these combined shifts and changes, the paper discusses the implications for rural poverty and food security, food safety and quality but also for diet-related non-communicable diseases and the related, emerging challenges for policymakers.
Tipo: Journal Article Palavras-chave: Food policy; Food systems; Nutrition; Food insecurity; Undernutrition; Malnutrition; Urbanization; Agricultural and Food Policy; Food Consumption/Nutrition/Food Safety; Food Security and Poverty.
Ano: 2004 URL: http://purl.umn.edu/12000
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Ethanol in low chronic dose level attenuates major organic effects in malnourished rats Biol. Res.
AGUIAR,ALINE S DE; BOAVENTURA,GILSON T; ABRAHÃO,RAFAEL F; FREITAS,THATIANA L; TAKIYA,CHRISTINA M; FILHO,PORPHIRIO J S; SILVA,VILMA A DA.
The aim of the present study was to evaluate the chronic toxicity of ethanol low blood levels in malnourished rats. Female Wistar rats (220 g) were subjected to either an ad libitum diet (W, well-nourished, n=10) or food restriction (M, malnourished, n=10). Water (WW and MW) or ethanol solution (W5% and M5%) was offered to half of each nutritional group (n=5) as the only fluid source. The treatment was continued for two months. After sacrifice, blood biochemical parameters and macroscopic, histologic and morphometric evaluation of the liver were performed. Results indicated that: Ethanol consumption was higher in malnourished rats and minimized body weight loss in malnourished rats, while it decreased the body weight gain in well-nourished ones. Behavioral...
Tipo: Journal article Palavras-chave: Ethanol; Low dose; Malnutrition; Toxicity.
Ano: 2009 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000100004
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Food Consumption Parameters for Brazil and their Application to Food Policy AgEcon
Gray, Cheryl Williamson.
As success is achieved in raising agricultural output and incomes in general, increased attention is being paid to improving the incomes and nutritional status of the lower-income, more disadvantaged peoples. Food subsidies have become an increasingly important means of transferring income to the poor. Because low-income people spend a much higher proportion of their income on food, food is a relatively efficient area for use of subsidies. They increase nutritional status more than other sources of income (see IFPRI Research Report 5, Impact of Subsidies Rice on Food Consumption and Nutrition in Kerala, by Shubh Kumar), and they have greater political acceptance among those with higher incomes, making them an attractive means if innocent transfer. However,...
Tipo: Report Palavras-chave: Nutrition surveys; Brazil; Nutrition policy; Malnutrition; Agricultural and Food Policy; Food Consumption/Nutrition/Food Safety.
Ano: 1982 URL: http://purl.umn.edu/42214
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Food intake and weight of lactating rats maintained on different protein-calorie diets, and pup growth BJMBR
Cambraia,R.P.B.; Vannucchi,H.; De-Oliveira,L.M..
Studies on rats maintained on low-protein-calorie diets during the lactation period show that food intake decreases. This process results in weight loss and a delay in litter development. The purpose of the present study was to determine the alterations in food intake, maternal weight and litter growth during lactation when dams were exposed to diets with different levels of protein and carbohydrate. Female Wistar rats receiving one of 4 different diets, A (N = 14), B (N = 14), C (N = 9) and D (N = 9), were used. Diet A contained 16% protein and 66% carbohydrate; diet B, 6% protein and 77% carbohydrate; diet C, 6% protein and 66% carbohydrate; diet D, 16% protein and 56% carbohydrate. Thus, C and D diets were hypocaloric, while A and B were isocaloric. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lactation; Malnutrition; Low-protein-calorie diet; Feeding behavior; Weight and growth of rats.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800012
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Food Security Analysis and Policies for Transition Countries AgEcon
Wehrheim, Peter; Wiesmann, Doris M..
This article explores the characteristics of food security in the context of economies in transition. These special characteristics derive from the “legacies” of socialist systems, both economy-wide ones and others specific to the agriculture and the food sector. Food insecurity in transition countries is considered predominantly “transitory”, while social safety nets dating back to the socialist years provide some cushion. Market failures and other institutional constraints are prevalent, inhibiting the process towards improvement of the food security situation. Conflict takes a heavy toll in terms of hunger and malnutrition in economies in transition and macro level factors are at work to determine food security outcomes. At the same time, socialist...
Tipo: Journal Article Palavras-chave: Food security; Poverty; Malnutrition; Transition countries; Agriculture; Agricultural policy; Safety nets; Food Security and Poverty.
Ano: 2006 URL: http://purl.umn.edu/112604
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Food security and livestock: The case of Latin America and the Caribbean Ciencia e Investigación Agraria
Rodríguez,Diego Ignacio; Anríquez,Gustavo; Riveros,José Luis.
The main hurdle to achieving food security in Latin America and the Caribbean is the inability of many poor families to access the foods necessary for a healthy diet, in a context in which food prices and family incomes are fundamental determinants. Animal husbandry plays a key role in the food security of the region, providing products rich in high-quality proteins and micronutrients and is vital for millions of households that depend on livestock for their livelihoods to generate income and have access to basic services. Furthermore, the production and trade of livestock products contributes to the stabilization of the food supply, acting as a buffer during economic crises and disasters both at the individual and community levels. Small farm agriculture...
Tipo: Journal article Palavras-chave: Food policies; Food security; Latin America; Livestock; Malnutrition; Rural livelihood; Small farm agriculture.
Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-16202016000100001
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Impact of malnutrition on immunity and infection J. Venom. Anim. Toxins incl. Trop. Dis.
França,TGD; Ishikawa,LLW; Zorzella-Pezavento,SFG; Chiuso-Minicucci,F; da Cunha,MLRS; Sartori,A.
Malnutrition may be a consequence of energy deficit or micronutrient deficiency. It is considered the most relevant risk factor for illness and death, particularly in developing countries. In this review we described the magnitude of this problem, as well as its direct effect on the immune system and how it results in higher susceptibility to infections. A special emphasis was given to experimental models used to investigate the relationship between undernutrition and immunity. Malnutrition is obviously a challenge that must be addressed to health authorities and the scientific community.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Malnutrition; Infection; Immunity; Experimental models.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300003
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Impairment of the hematological response and interleukin-1β production in protein-energy malnourished mice after endotoxemia with lipopolysaccharide BJMBR
Fock,R.A.; Vinolo,M.A.R.; Blatt,S.L.; Borelli,P..
The objectives of this study were to determine if protein-energy malnutrition (PEM) could affect the hematologic response to lipopolysaccharide (LPS), the interleukin-1β (IL-1β) production, leukocyte migration, and blood leukocyte expression of CD11a/CD18. Two-month-old male Swiss mice were submitted to PEM (N = 30) with a low-protein diet (14 days) containing 4% protein, compared to 20% protein in the control group (N = 30). The total cellularity of blood, bone marrow, spleen, and bronchoalveolar lavage evaluated after the LPS stimulus indicated reduced number of total cells in all compartments studied and different kinetics of migration in malnourished animals. The in vitro migration assay showed reduced capacity of migration after the LPS stimulus in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood; Bone marrow; Spleen; Interleukin-1β; Lipopolysaccharide; Malnutrition.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001200009
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Importance of the nutritional status for the interpretation of nuclear medicine examinations BABT
Moura,Egberto Gaspar de; Passos,Magna Cottini Fonseca.
Malnutrition is very prevalent in the Third World, but still in developing Countries and is found in certain communities in developed Countries. Several laboratories examinations are affected by malnutrition. Recently, gestational or neonatal malnutrition were considered to contribute to the development of chronic diseases in adulthood, this phenomena was named programming or metabolic imprinting. Similar consideration were suggested for Nuclear Medicine examinations. Here we review the literature about this aspect and present our own data showing changes in biodistribution of a radiopharmaceutical compound in different animal models of adult malnutrition or caused by maternal malnutrition programming.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Programming; Nuclear Medicine; Malnutrition; Biodistribution; Radiopharmaceuticals.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000500021
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Increased production of tumor necrosis factor-alpha in whole blood cultures from children with primary malnutrition BJMBR
Azevedo,Z.M.A.; Luz,R.A.; Victal,S.H.; Kurdian,B.; Fonseca,V.M.; Fitting,C.; Câmara,F.P.; Haeffner-Cavaillon,N.; Cavaillon,J.-M.; Gaspar Elsas,M.I.C.; Xavier Elsas,P..
Because low tumor necrosis factor-alpha (TNF-alpha) production has been reported in malnourished children, in contrast with high production of TNF-alpha in experimental protein-energy malnutrition, we reevaluated the production of TNF-alpha in whole blood cultures from children with primary malnutrition free from infection, and in healthy sex- and age-matched controls. Mononuclear cells in blood diluted 1:5 in endotoxin-free medium released TNF-alpha for 24 h. Spontaneously released TNF-alpha levels (mean ± SEM), as measured by enzyme immunoassay in the supernatants of unstimulated 24-h cultures, were 10,941 ± 2,591 pg/ml in children with malnutrition (N = 11) and 533 ± 267 pg/ml in controls (N = 18) (P < 0.0001). TNF-alpha production was increased by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: TNF-alpha; Malnutrition; LPS.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200005
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Malnutrition affects the pressor response to microinjection of L-glutamate into the RVLM of awake rats Biol. Res.
Rodrigues,Fabiana Aparecida; Chianca-Jr,Deoclecio Alves; Gonçalves Fernandes,Luciano.
Post-weaning protein malnutrition is often related to the development of cardiovascular and metabolic diseases in humans, as well to changed content of neurotransmitters in the central nervous system under experimental conditions. The rostral ventrolateral medulla (RVLM) is a bulbar region that contains sympathetic premotor neurons; the excitatory amino acid L-glutamate seems to be the main neurotransmitter at this level. The aim of the present study was to evaluate the possible change in the L-glutamate sensitivity of the RVLM neurons of malnourished animals. Male Fischer rats were divided into two groups: control (n = 15) and malnourished (n = 19). Four days before the experiments, guide cannulas were implanted bilaterally in direction of the RVLM for...
Tipo: Journal article Palavras-chave: Baroreflex; Blood pressure; L-glutamate receptors; Heart rate; Malnutrition; RVLM.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400002
Registros recuperados: 36
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