|
|
|
|
|
| Rodríguez,Arsenio; Infante,Diogenes. |
| The systematic study of the genetic fingerprint (genomics) and the biochemistry (metabolites) that goes with a specific cellular process requires the characterization of all the small molecules that form the profile of metabolites and the associated genes. The metabolome represents the collection of all the metabolites during certain process in an organism. The transcriptome represents the gene expression profile, all the messengers RNA in a defined condition. Then to understand the whole process, the studies of metabolites must be accompanied with studies of the gene expression, hence the metabolome must be accompanied by the transcriptome, so we can identify genes and metabolites whose synthesis is induced by a specific process, an infection or stress.... |
| Tipo: Journal article |
Palavras-chave: Graph theory; Metabolic networks; Metabolomic. |
| Ano: 2009 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582009000400011 |
| |
|
|
| Georges Des Aulnois, Maxime; Roux, Pauline; Caruana, Amandine; Réveillon, Damien; Briand, Enora; Hervé, Fabienne; Savar, Veronique; Bormans, Myriam; Amzil, Zouher; Atomi, Haruyuki. |
| Proliferation of microcystin (MC)-producing Microcystis aeruginosa in brackish waters has been described in several locations and represents a new concern for public and environmental health. While the impact of a sudden salinity increase on M. aeruginosa physiology has been studied, less is known about the mechanisms involved in salt tolerance after acclimation. This study aims to compare the physiological responses of two strains of M. aeruginosa (PCC 7820 and PCC 7806), which were isolated from contrasted environments, to increasing salinities. After acclimation, growth and MC production rates were determined and metabolomic analyses were conducted. For both strains, salinity decreased the biovolume, growth, and MC production rates and induced the... |
| Tipo: Text |
Palavras-chave: Acclimation; Metabolomic; Microcystis; Salinity; Sucrose; Trehalose; Ecophysiology. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00588/70031/68012.pdf |
| |
|
|
| Georges Des Aulnois, Maxime; Réveillon, Damien; Robert, Elise; Caruana, Amandine; Briand, Enora; Guljamow, Arthur; Dittmann, Elke; Amzil, Zouher; Bormans, Myriam. |
| The transfer of Microcystis aeruginosa from freshwater to estuaries has been described worldwide and salinity is reported as the main factor controlling the expansion of M. aeruginosa to coastal environments. Analyzing the expression levels of targeted genes and employing both targeted and non-targeted metabolomic approaches, this study investigated the e ect of a sudden salt increase on the physiological and metabolic responses of two toxic M. aeruginosa strains separately isolated from fresh and brackish waters, respectively, PCC 7820 and 7806. Supported by di erences in gene expressions and metabolic profiles, salt tolerance was found to be strain specific. An increase in salinity decreased the growth of M. aeruginosa with a lesser impact on the... |
| Tipo: Text |
Palavras-chave: Microcystis aeruginosa; Microcystin; Salt stress; Metabolomic; Transcript. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00615/72689/71692.pdf |
| |
|
|
|
