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| Lyon,Juliana P.; Moraes,Karen C.M.; Moreira,Leonardo M.; Aimbire,Flávio; Resende,Maria Aparecida de. |
| Several molecular methods, such as Southern blotting hybridization, Multilocus Sequence Typing, and DNA microsatellite analysis, have been employed to genotype Candida albicans. The genotype analysis allows to group strains in clades, that is, a group composed of one ancestor and its descendants. These genotype studies demonstrate that clades distribution is influenced by geographic area as well as that antifungal resistance is associated with particular clades. These findings suggested that C. albicans reproduces mainly in a clonal manner, with certain degree of DNA microevolution. Additionally, virulence factors and site of isolation have also been associated with clade specificity. The present article is a brief review about the methods used for Candida... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida albicans; Clonal reproduction; Microevolution; Genotyping systems; Phenotypic characteristics. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000400003 |
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| NESPOLO,ROBERTO F. |
| Evolutionary biology is experiencing an exceptional process of revisión and outreach because of the 200-anniversary if the birth of Charles Darwin. As a consequence, the study of organic evolution and also its teaching are being discussed at several levels, by evolutionary biologists, biologists and scholars outside evolutionary biology and by the general public. In this scenario, a didactic explanation of how biologists address evolutionary research in real populations seems to be useful. Using actual research examples, here I tried to outline how the classic theory (termed here as the "basic scheme") is useful to answer relevant questions in biology and how a less dogmatic paradigm (or a more versatile one) would be needed when dealing with the most... |
| Tipo: Journal article |
Palavras-chave: Character displacement; Microevolution; Modern synthesis; Natural selection; Population genetics. |
| Ano: 2010 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2010000400003 |
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