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	Provedor de dados ArchiMer (2) Autor Bachere, Evelyne (2) Alonso, Pascal (1) Bruno, Roman (1) De Lorgeril, Julien (1) Piquemal, David (1) Rosa, Rafael D. (1) Rosa, Rafael Diego (1) Santini, Adrien (1) Tailliez, Patrick (1) Vergnes, Agnes (1) Mais... Palavra-chave Mollusk bivalve (2) Polymorphism (2) Antimicrobial peptide (1) Digital gene expression (1) Gene copy number (1) Gene copy number variation (1) High-throughput microfluidic RT-qPCR (1) Marine invertebrate (1) Mass mortality (1) Microfluidic qPCR (1) Survival predictive biomarkers (1) Survival signature (1) Transcriptome-wide analysis (1) Vibrio infection (1) Mais... Tipo do documento Text (2) Ano 2015 (1) 2012 (1) País France (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última A hemocyte gene expression signature correlated with predictive capacity of oysters to survive Vibrio infections ArchiMer Rosa, Rafael Diego; De Lorgeril, Julien; Tailliez, Patrick; Bruno, Roman; Piquemal, David; Bachere, Evelyne. Background: The complex balance between environmental and host factors is an important determinant of susceptibility to infection. Disturbances of this equilibrium may result in multifactorial diseases as illustrated by the summer mortality syndrome, a worldwide and complex phenomenon that affects the oysters, Crassostrea gigas. The summer mortality syndrome reveals a physiological intolerance making this oyster species susceptible to diseases. Exploration of genetic basis governing the oyster resistance or susceptibility to infections is thus a major goal for understanding field mortality events. In this context, we used high-throughput genomic approaches to identify genetic traits that may characterize inherent survival capacities in C. gigas. Results:... Tipo: Text Palavras-chave: Marine invertebrate; Mollusk bivalve; Mass mortality; Transcriptome-wide analysis; Digital gene expression; Microfluidic qPCR; Survival signature; Polymorphism; Gene copy number; Survival predictive biomarkers. Ano: 2012 URL: http://archimer.ifremer.fr/doc/00095/20624/18262.pdf High polymorphism in big defensin gene expression reveals presence-absence gene variability (PAV) in the oyster Crassostrea gigas ArchiMer Rosa, Rafael D.; Alonso, Pascal; Santini, Adrien; Vergnes, Agnes; Bachere, Evelyne. We report here the first evidence in an invertebrate, the oyster Crassostrea gigas, of a phenomenon of Presence-Absence Variation (PAV) affecting immune-related genes. We previously evidenced an extraordinary interindividual variability in the basal mRNA abundances of oyster immune genes including those coding for a family of antimicrobial peptides, the big defensins (Cg-BigDef). Cg-BigDef is a diverse family composed of three members: Cg-BigDef1 to -3. Here, we show that besides a high polymorphism in Cg-BigDef mRNA expression, not all individual oysters express simultaneously the three Cg-BigDefs. Moreover, in numerous individuals, no expression of Cg-BigDefs could be detected. Further investigation at the genomic level revealed that in individuals in... Tipo: Text Palavras-chave: Mollusk bivalve; Antimicrobial peptide; Polymorphism; Gene copy number variation; High-throughput microfluidic RT-qPCR; Vibrio infection. Ano: 2015 URL: https://archimer.ifremer.fr/doc/00239/35009/33545.pdf Registros recuperados: 2 Primeira ... 1 ... Última

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