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Gómez-Estrada,Harold; Gaitán-Ibarra,Ricardo; Díaz-Castillo,Fredyc; Pérez,Hilda A; Medina,José D. |
Introduction: in vitro antimalarial activity of naphthoquinones (1-5), isolated from Tabebuia billbergii (Bureau & K. Schum.) Standl., was investigated. Tabebuia billbergii, commonly known as guayacán, is a plant traditionally used in the Amazon in numerous conditions like bacterial and fungal infections, fever, syphilis, malaria, trypanosomiasis, as well as stomach and bladder disorders, and tumours. Objective: to study the dichloromethane extracts of both the trunk and the inner bark of Tabebuia billbergii and to demonstrate the antimalarial activity of some of its bioactive components. Methods: some bioactive components were evaluated for the antimalarial activity against Plasmodium berghei, by using the inhibition of the differentiation cycle... |
Tipo: Journal article |
Palavras-chave: Tabebuia billbergii; Naphthoquinones; Plasmodium berghei. |
Ano: 2012 |
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962012000200006 |
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