|
|
|
Registros recuperados: 18 | |
|
| |
|
|
Cardoso,Saulo Pereira; Mattioli,Mariana Portugal; Borges,Betânia Pereira; Blume,Guilherme Reis; Reis Júnior,Janildo Ludolf; Sant'Ana,Fabiano José Ferreira de. |
ABSTRACT: Primary gallbladder neoplasms occur infrequently in domestic animals and rarely in wild animals. This article describes a case of gallbladder adenoma in a mongoose ( Mungos mungo) in captivity. Grossly, the gallbladder was moderately distended with a smooth capsular surface. Necropsy showed an irregular, soft, whitish nodule 0.8cm in diameter. Microscopic examination of the nodule showed proliferation of epithelial cells, which projected from the mucosa and formed papillary projections supported by a sparse fibrovascular stroma. Neoplastic cells were well differentiated with mild anisocytosis and anisokaryosis. Based on these histopathological findings, adenoma of the gallbladder was diagnosed. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oncology; Neoplasia; Wild animals.. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000701249 |
| |
|
|
Cunha,R.M.C.; Lavalle,G.E.; Reis,D.C.; Horta,R.S.; Teixeira,S.V.; Ramirez,J.A.; Araújo,R.B.. |
ABSTRACT Electrochemotherapy is a local anticancer treatment in which non-permeant chemotherapeutic drugs are associated with electric pulses of well-established parameters. The electric pulses cause pores to open on the plasma membrane and facilitate drug transport, enhancing cytotoxicity and reducing side effects. Assessment of electrochemotherapy effects on Ehrlich solid tumor development in this work aims to evaluate in vivo usage of the electroporator device developed by the Department of Electrical Engineering of Engineering School of UFMG. Therefore, 40 Swiss mice were inoculated with Ehrlich tumor cells, and developed the tumor in solid form. After 21 days, mice were subjected to specific treatment protocols (control, bleomycin, electric pulses and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mouse; Oncology; Electrochemotherapy; Experimental tumor. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601581 |
| |
|
|
Teixeira,N.C.T.; Bicalho,A.P.C.V.; Vasconcelos,A.V.; Horta,R.S.; Cunha,R.M.C.; Lavalle,G.E.. |
ABSTRACT Metronomic chemotherapy consists of an anticancer modality treatment. It is applicable in patients at an advanced stage, with the objective of increasing overall survival. The aim of this study was to report an anal sac apocrine carcinoma case in a dog with lymph node metastasis treated with metronomic chemotherapy sequential to surgery and conventional chemotherapy using gemcitabine and carboplatin. Metronomic chemotherapy was associated with cyclooxygenase-2 (COX-2) inhibitors, due to strong tumor COX-2 immunohistochemistry expression. Metronomic chemotherapy was initiated with cyclophosphamide, but it was replaced by lomustine, also in metronomic dosage, due to adverse effects. Treatment showed effectiveness, since the patient's overall... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Oncology; Angiogenesis inhibitor; Cyclophosphamide; Lomustine. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000400913 |
| |
|
| |
|
| |
|
| |
|
|
Dias,F.G.G.; Cintra,P.P.; Calazans,S.G.; Jorge,A.T.; Pereira,L.F.; Dias,L.G.G.G.; Olivio,M.B.; Magalhães,G.M.. |
ABSTRACT The larynx is part of the upper respiratory tract and is responsible for phonation. It allows air to pass between the pharynx and the trachea, but prevents food from entering the airways. Laryngeal neoplasms, including rhabdomyosarcomas, are uncommon in dogs. However, these tumors can trigger numerous progressive clinical signs related to respiratory difficulty and altered phonation. The diagnosis of laryngeal cancer should be made based on the history and symptoms of the patient, combined with complementary tests. The treatment of choice is surgical excision, combined or not with chemotherapy. In view of the low incidence of laryngeal cancer, the objective of the present work was to describe a case of laryngeal rhabdomyosarcoma detected during... |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Oncology; Small animals; Rhabdomyosarcoma; Respiratory system. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000501423 |
| |
|
|
Salvador-Bernabé,Rosana Lino; Tinucci-Costa,Mirela; Amorim,Renee Laufer. |
ABSTRACT: Mammary tumors are the most frequent tumors reported in female dogs and have great relevance in veterinary oncology; however, little is known about the molecular mechanisms involved in the development of metastasis. An increasing number of human studies have suggested that epigenetic alterations, such as DNA methylation, miRNA, and histone modifications, are the predominant events leading to the metastatic phenotype in tumor cells and participate in regulating oncogenic signals associated with tumor spread. Among these epigenetic alterations, miRNAs have stood out in recent years, presenting a fundamental role in tumorigenesis. There are still few studies evaluating the role of miRNAs in canine mammary tissues. Thus, this paper aims to review... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oncology; Dog; Mammary carcinoma; MiRNA. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018001100600 |
| |
|
|
Tochetto,Camila; Rosa,Fábio Brum; Santos,Rosmarini Passos dos; Mazzanti,Alexandre; Fighera,Rafael Almeida; Kommers,Glaucia Denise. |
This case report describes the clinical, histopathological and immunohistochemical findings in two dogs with myelopathy associated with metastasis of follicular-compact thyroid carcinoma. Microscopically, both primary neoplasms were characterized by polygonal cells arranged in follicles (occasionally filled with eosinophilic colloid-like material) or in sheets. The neoplastic cells had a moderately eosinophilic cytoplasm and there was moderate anisokaryosis and anisocytosis. Additionally, the neoplastic cells were positive for thyroglobulin on immunohistochemistry, confirming the follicular origin of both tumors. This is a very uncommon presentation of this pathological condition. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunohistochemistry; Oncology; Thyroid tumor; Neurooncology.. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000801487 |
| |
|
|
Ferreira,M.G.P.A.; Antunes,A.V.; Pascoli,A.L.; Nazaret,T.L.; Gering,A.P.; Reis Filho,N.P.; Costa,M.T.; Nardi,A.B.. |
ABSTRACT Neuropathic pain occurs when there is a lesion or a dysfunction of the nervous system. Humans and veterinary patients may develop neuropathic pain, but in veterinary it is not often reported probably because of its mistaken diagnosis. A canine patient was admitted to the Veterinary Hospital of UNESP-Jaboticabal-SP, Brazil with a nodule on the left thoracic limb. The nodule was surgically removed, and histopathological analysis demonstrated the tumor was a soft tissue sarcoma (STS) and the margins were not clean. Based on the patient’s health condition and the lack of suitable equipment, the next procedure was limb amputation. The patient received analgesic medication in the post-surgery period; nevertheless, clinical signs of neuropathic pain were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Analgesia; Oncology; Phantom limb; Radiotherapy; Tumor. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401116 |
| |
|
|
Ferreira,M.G.P.A.; Ribeiro,J.O.; Pascoli,A.L.; Reis-Filho,N.P.; Beluque,T.; Santos,M.Q.P.; Theodoro,S.S.; Feliciano,M.A.R.; Nardi,A.B.; Tinucci-Costa,M.; Moraes,P.C.; Canola,J.C.; Carciofi,A.C.. |
ABSTRACT The aim of this report was to describe the clinical findings and therapeutic management of a case of papillary adenocarcinoma of the descending colon in a Beagle. The patient presented soft stools, haematochezia, tenesmus, and dyschezia. Clinical examination revealed alterations on the ultrasonographic features of the descending colon suggestive of colitis and neoplasia. Following local mass resection, histopathology analysis revealed mild lymphoplasmocytic enteritis and papillary adenocarcinoma of the colon. Enterectomy for tumoral resection and biopsy of locoregional lymph nodes were carried out. Subsequent to the surgical procedure, it was possible to confirm the previous diagnosis and the tumor was classified as intestinal intraluminal... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Canine; Intestinal neoplasia; Oncology. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000400830 |
| |
|
| |
|
|
Moro,J.V.; Tinucci-Costa,M.; Silveira,A.C.T.; Gerardi,D.G.; Alessi,A.C.. |
The expression of p53 protein was evaluated in canine transmissible venereal tumor (CTVT), as following: natural occurrence (n=8); resistant to chemotherapy (n=4); and allogeneic transplanted in progression (n=8), stable (n=8), and regression (n=8)stages. The collected specimens were submitted to GM1 immunohistochemical reaction. Results showed a mean percentage of immunomarked cells around 18.6% in CTVT of natural occurrence, 23.8% in CTVT resistant to chemotherapy, 22.9% in allogeneic transplanted CTVT in both progression and stable stages, and 35.8% in transplanted CTVT in regression stage. The results suggest that there is a functional abnormality in p53 gene and its products in the studied tumors; although, it is not possible to correlate the... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunohistochemistry; P53; Oncology; Transmissible venereal tumor. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352010000200011 |
| |
|
| |
|
| |
|
|
Oliveira,A.R.; Flecher,M.C.; Horta,R.S.; Souza,M.C.C.; Hardt,I.; Gonçalves,A.B.B.; Cassali,G.D.; Souza,T.D.. |
ABSTRACT Intestinal carcinomas are rare in dogs. The prognosis and survival time are dependent of the histological type, the invasion of the intestinal wall by the malignant cells and the ability of primary neoplasm to produce metastasis. This study reports a case of a Yorkshire dog that developed a rectal tubulopapillary adenocarcinoma progressing to a peritoneal carcinomatosis and multiple metastasis in large intestines, bladder, kidney, iliac lymph node, liver and lungs, six months after transanal surgical resection of the primary rectal neoplasm. Clinical, surgical, pathological and immunophenotypic findings are described. COX-2 imunohistochemical score was higher in hepatic metastasis (score 9) than in the primary tumour (score 6), and the growth... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Enteric neoplasm; COX-2; Oncology; Carcinomatosis; Metastasis. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000200463 |
| |
|
|
Blume,Guilherme Reis; Oliveira,Ayisa Rodrigues de; Mattioli,Mariana Portugal; Oliveira,Letícia Batelli de; Reis Junior,Janildo Ludolf; Sant'Ana,Fabiano José Ferreira de. |
Chondrosarcoma is a malignant mesenchymal tumor in which the neoplastic cells produce cartilaginous matrix and is uncommonly described in birds. This report describes the clinical and pathological findings of one case of chondrosarcoma in a blue-fronted parrot (Amazona aestiva). Macroscopically a 3.6x3.5x1.8cm, nodular, ulcerated, and firm mass was identified in the dorsal synsacrum. Microscopically, the mass was composed of a monomorphic proliferation of pleomorphic spindle chondrocytes with abundant cartilaginous matrix, consistent with chondrosarcoma |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Oncology; Psittacine; Neoplasm. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000300525 |
| |
Registros recuperados: 18 | |
|
|
|