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A model for the study of skeletal anomalies in rat fetuses BABT
Effting,Cristiane; Paula,Daniel Jesus de; Nunes Junior,Guilhermino Pereira.
The aim of this study was to validate a model of skeletal anomalies in rat fetuses by the administration of ketoconazole (80 mg/kg) to pregnant rats during organogenesis. Bones of the head, trunk and anterior and posterior limbs were examined for detection of anomalies. Statistical differences regarding the number of fetuses and postimplantation resorptions, and fetal and placental weight were significant. The frequency of skeletal anomalies in the head, trunk, and anterior and posterior limbs in the ketoconazole-treated group were also significant when compared to the control group. It could be concluded that the model suggested was valid for study of skeletal anomalies and abnormal bones development in rat fetuse, in spite of the loss of fetuses due to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Azol Antifungals; Ketoconazole; Models; Pregnancy; Skeletal Malformation; Steroids; Teratogenesis; Wistar Rats.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132004000100005
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Acceleration of reflex maturation and physical development in suckling rats: effects of a maternal diet containing lipids from goat milk. Repositório Alice
SOARES, J. K. B.; QUEIROGA, R. de C. R. do E.; BOMFIM, M. A. D.; PESSOA, D. C. N. de P.; BARBOSA, E. de A.; SOUZA, D. L.; CABRAL-FILHO, J. E.; MEDEIROS, M. do C..
Objective: To investigate the effects of lipids from goat milk containing conjugated linoleic acids on body weight and reflex ontogeny of neonatal rats treated during the prenatal and suckling periods. Methods: Three groups were studied: soybean oil (S), coconut oil (C), and goat milk lipids (GM). Reflex maturation (palm grasp, righting reflex, cliff avoidance, vibrissae placing, negative geotaxis, auditory startle, and free-fall righting) as well as body weight evolution were recorded during lactation. Results: Data demonstrated that the lipids from goat milk accelerated body weight evolution as well as all the reflex maturation investigated (P < 0.05). Discussion: The supply of goat?s milk offered to Wistar rats during pregnancy and lactation provided...
Tipo: Artigo de periódico Palavras-chave: Maternal nutritional; Dosage effects; Plant oils.; Fats; Leite de cabra; Caprino; Aleitamento; Lactação; Óleo vegetal; Soja; Dieta; Gordura; Prenhez; Coco; Cérebro; Ganho de peso; Goat milk; Goats; Rats; Weight; Suckling; Linoleic acid; Lactation; Drugs; Pregnancy; Soybean oil; Coconut oil; Brain; Conjugated linoleic acid..
Ano: 2014 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1005386
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Antiretroviral agents and acid-base balance at delivery of the neonate BJMBR
El-Beitune,P.; Duarte,G.; Morais,E.N. de; Campbell,O.; Spara-Gadelha,P.; Mauad-Filho,F.; Quintana,S.M.; Rodrigues,L.C..
Limited evidence is available regarding antiretroviral (ARV) safety for uninfected infants exposed to these drugs in utero. Our objective was to determine if ARV administered to pregnant women is associated with decreasing umbilical arterial pH and base excess in uninfected infants. A prospective study was conducted on 57 neonates divided into three groups: ZDV group, born to mothers taking zidovudine (N = 20), triple therapy (TT) group, born to mothers taking zidovudine + lamivudine + nelfinavir (N = 25), and control group (N = 12), born to uninfected mothers. Umbilical cord blood was used to determine umbilical artery gases. A test was performed to calculate the sample by comparing means by the unpaired one-tailed t-test, with a = 0.05 and ß = 20%,...
Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV; Infant toxicity; Pregnancy; Umbilical arterial pH; Apgar scores.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000700010
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Assessment of fetal risk associated with exposure to cancer chemotherapy during pregnancy: a multicenter study BJMBR
Peres,R.M.; Sanseverino,M.T.V.; Guimarães,J.L.M.; Coser,V.; Giuliani,L.; Moreira,R.K.; Ornsten,T.; Schüler-Faccini,L..
The objective of the present study was to evaluate and quantify fetal risks involved in the administration of cancer chemotherapy during gestation, as well as to assess the long-term effects on the exposed children. In this retrospective, cohort study, we reviewed the records of women aged 15 to 45 years with a diagnosis of malignancy or benign tumors with malignant behavior at three reference services in the State of Rio Grande do Sul, Brazil, from 1990 to 1997. All patients with a diagnosis of pregnancy at any time during the course of the disease were selected, regardless of whether or not they received specific medication. Fetal outcomes of 14 pregnancies with chemotherapy exposure were compared to that of 15 control pregnancies in which these drugs...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Pregnancy; Chemotherapy; Teratogenicity; Fetal outcome.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001200007
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Associação do efeito macho e duas doses cloprostenol para indução de estro sincronizados em ovelhas Santa Inês na região da Mata Atlântica de Minas Gerais. Repositório Alice
PRATES, J. F.; OLIVEIRA, F. R. B. de; MAIA, A. L. R. de S.; PENIDO, P. P. do N.; FERREIRA, M. I. C.; FONSECA, J. F. da.
[Association of the male effect and two doses of cloprostenol to induce synchronous estrus in Santa Inês Sheep in the Atlantic Forest of Minas Gerais]
Tipo: Parte de livro Palavras-chave: Raça Santa Inês; Efeito macho; Indução do estro; Taxa de prenhez; Oestrous cycle.; Ovino; Ciclo estral; Reprodução animal; Sincronização do cio; Acasalamento; Sheep; Copulation; Pregnancy; Cloprostenol; Male effect..
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1019646
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Behavioral characteristics of the offspring of adolescent rats BJMBR
Zemunik,T.; Peruzovic,M.; Capkun,V.; Milkovic,K..
The aim of this study was to test the hypothesis that, during adulthood, the offspring of adolescent rats differ in emotionality, learning and memory from the offspring of adult rats. The behavior of the offspring of adolescent (age, 50-55 days) and adult rats (age, 90-95 days) was tested in the open field, activity cage, and passive and active avoidance apparatus. The latencies during training and testing in the passive avoidance apparatus of the offspring of adolescent parents were shorter than the latencies of control offspring (P<0.001 on both training and testing days). Offspring of adolescent parents showed shorter latency time in acquisition trials during active avoidance testing compared to control offspring (P<0.001). They also showed a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adolescence; Pregnancy; Behavior; Learning and memory; Emotionality.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400008
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Changes in maternal body composition and metabolism of dairy goats during pregnancy. Repositório Alice
CASTAGNINO, D. de S.; HüRTER, C. J.; RIVERA, A. R.; LIMA, L. D. de; SILVA, H. G. de O.; BIAGIOLI, B.; RESENDE, K. T. de; TEIXEIRA, I. A. M. de A..
Abstract: The objective of this study was to evaluate the mobilization of nutrients in goats of different gestation types and pregnancy stages. Forty-four Saanen and Oberhasli goats were studied. The goats of each breed and gestation type (single or twin) were slaughtered at different gestational ages (80, 110, and 140 days of pregnancy), forming a completely randomized design in a 2 × 3 × 2 factorial arrangement (two breeds, three gestational ages, and two types of pregnancy). The slaughter procedure involved separating the empty body, mammary glands, uterus with membranes and fetal fluid, and fetus(es). For the females slaughtered at 140 days of pregnancy, blood was collected to analyze metabolites and hormones every 15 days during gestation. The dry...
Tipo: Parte de livro Palavras-chave: Hormone profile; Perfil hormonal; Perfil metabólico; Nutritional profile; Pregnancy outcomes; Type of pregnancy; Caprino; Cabra; Nutrição animal; Nutriente; Prenhez; Ingestão; Goats; Energy metabolism; Animal nutrition; Nutrients; Pregnancy.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1040623
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Chronic Stress Effects on Adrenal Cortex Cellular Proliferation in Pregnant Rats International Journal of Morphology
Bozzo,Aída Andrea; Soñez,Carlos Alberto; Monedero Cobeta,Ignacio; Avila,Rodolfo; Rolando,Alicia Nélida; Romanini,María Cristina; Lazarte,Mario; Gauna,Héctor Fernando; Mugnaini,María Teresa.
Chronic stress by immobilization during pregnancy may cause alterations in mechanisms maintaining homeostasis in the adrenal gland. The objective of this study was to quantify cellular proliferation index in the adrenal cortex during pregnancy second half and assess the effects of chronic stress on it. Adrenal cortex proliferation index in stressed rats showed a significant decrease at 12 and 17 days of gestation, while at day 21 it did not show differences with the control treatments. Moreover, proliferation index of reticular zones in control and experimental rats, exhibited a significant reduction in comparison to glomerular and fascicular zones of adrenal cortex during the three gestation days studied. In conclusion, chronic stress by immobilization...
Tipo: Journal article Palavras-chave: Chronic stress; Cellular proliferation; Adrenal cortex; Pregnancy.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400013
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Chronic stress effects on the apoptotic index of the adrenal cortex of pregnant rats Biocell
Bozzo,Andrea; Soñez,Carlos Alberto; Mugnaini,María Teresa; Pastorino,Isabel Cecilia; Rolando,Alicia Nélida; Romanini,María Cristina; Gauna,Héctor Fernando.
Chronic stress by immobilization during gestation can alter several mechanisms that maintain homeostasis in adrenal gland. The aim of this work was to quantify the apoptotic index of adrenal cortex during mid-pregnancy and to prove cytological characteristics by electron microscopy. The apoptotic index did not present significant differences between the adrenal cortex areas of control and experimental rats in any of the three ages studied. The day of gestation influenced significantly on the apoptotic index in both groups. This index increased as gestation progressed. It may be concluded that chronic stress by immobilization might induce the increase of apoptotic index in adrenal cortex as gestation progresses which might be related variations of plasmatic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic stress; Apoptosis; Adrenal cortex; Pregnancy.
Ano: 2006 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000300004
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Ciclo estral e período de gestação de cabras Sem Raça Definida (SRD). Repositório Alice
SIMPLICIO, A. A.; NUNES, J. F.
Tipo: Anais e Proceedings de eventos Palavras-chave: Raça SRD; Oestrous cycle; Caprino; Cabra; Ciclo estral; Prenhez; Período de gestação; Reprodução animal; Goats; Gestation period; Animal reproduction; Pregnancy; Brazil.
Ano: 1978 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/948286
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Colonization by Streptococcus agalactiae during pregnancy: maternal and perinatal prognosis BJID
El Beitune,Patrícia; Duarte,Geraldo; Maffei,Cláudia Maria Leite.
We reviewed colonization by group B Streptococcus beta-haemolyticus of Lancefield (SGB), or Streptococcus agalactiae, in pregnant women, and the consequences of infection for the mother and newborn infant, including factors that influence the risk for anogenital colonization by SGB. We also examined the methods for diagnosis and prophylaxis of SGB to prevent early-onset invasive neonatal bacterial disease. At present, it is justifiable to adopt anal and vaginal SGB culture as part of differentiated obstetrical care in order to reduce early neonatal infection. The rates, risk factors of maternal and neonatal SGB colonization, as well as the incidence of neonatal disease, may vary in different communities and need to be thoroughly evaluated in each country...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pregnancy; Prognosis; Streptococcus agalactiae.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000400002
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Combined effect of short stature and socioeconomic status on body mass index and weight gain during reproductive age in Brazilian women BJMBR
Sichieri,R.; Silva,C.V.C.; Moura,A.S..
Short stature, a marker for undernutrition early in life, has been associated with obesity in Brazilian women, but not in men. We tested the hypothesis that weight gain during the reproductive years could explain this gender difference. A national two-stage household survey of mothers with one or more children under five years of age was conducted in Brazil in 1996. The subjects were women aged 20 to 45 years (N = 2297), with last delivery seven months or more prior to the interview. The regions of the country were divided into rural, North/Northeast (urban underdeveloped) and South/Southeast/Midwest (urban developed). The dependent variables were current body mass index (BMI) measured, BMI prior to childbearing (reported), and BMI change. Socioeconomic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Parity; Body mass index; Weight gain; Pregnancy; Overweight; Stature.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000007
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Comparative analysis of two different models of swimming applied to pregnant rats born small for pregnant age Anais da ABC (AABC)
CORVINO,SILVANA B.; DAMASCENO,DÉBORA C.; SINZATO,YURI K.; NETTO,ALINE O.; MACEDO,NATHÁLIA C.D.; ZAMBRANO,ELENA; VOLPATO,GUSTAVO T..
ABSTRACT The aim of this study was to compare two models of swimming applied to pregnant rats born small for pregnancy age (SPA). Diabetes was chemically induced in adult female rats to develop an inadequate intrauterine environment, leading to birth of a SPA offspring. In adulthood, the female SPA rats were mated and submitted to different swimming programs. The exercise program 1 (Ex1) consisted of swimming for 15 minutes, followed by 15 minutes of rest and another 15 minutes of swimming, 3 days a week before and during pregnancy. Another program (Ex2) was applied during 60 minutes uninterrupted a day, 6 days/week during pregnancy. The pregnant rats presented no interference on body weight and glycemia. The rats submitted to Ex2 model showed decreased...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rats; Diabetes; Pregnancy; Offspring; Exercise..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100223
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Concentrações séricas de proteína total, glicose, fosforo, cálcio e magnésio durante gestação e lactação em caprinos, fêmeas mantidas em pastagem nativa. Repositório Alice
SILVA, A. E. D. F.; SILVA, M. U. D..
Tipo: Anais e Proceedings de eventos Palavras-chave: Brasil; Ceara.; Caprino; Prenhez; Lactação; Bioquímica animal; Goats; Pregnancy; Lactation; Biochemical compounds; Brazil..
Ano: 1984 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/515114
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Congenitally transmitted visceral leishmaniasis: report of two brazilian human cases BJID
Mescouto-Borges,Myrlena Regina Machado; Maués,Érika; Costa,Dorcas Lamounier; Pranchevicius,Maria Cristina da Silva; Romero,Gustavo Adolfo Sierra.
Visceral leishmaniasis is a relevant public health problem worldwide. Most of the reported cases in Latin America are from Brazil. Herein we report two human cases of congenitally transmitted visceral leishmaniasis in two patients who developed symptoms during pregnancy. The diagnosis was made by visual examination of Leishmania parasites in bone marrow aspirates of the mothers and by detecting parasite kDNA in bone marrow samples of the newborn children using polymerase chain reaction.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Congenital transmission; Visceral leishmaniasis; Leishmania infantum; Pregnancy.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200024
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Correlation of serum leptin and insulin levels of pregnant protein-restricted rats with predictive obesity variables BJMBR
Macêdo,G.S.; Ferreira,C.L.P.; Menegaz,A.; Arantes,V.C.; Veloso,R.V.; Carneiro,E.M.; Boschero,A.C.; Oller do Nascimento,C.M.P.; Latorraca,M.Q.; Gomes-da-Silva,M.H.G..
During pregnancy and protein restriction, changes in serum insulin and leptin levels, food intake and several metabolic parameters normally result in enhanced adiposity. We evaluated serum leptin and insulin levels and their correlations with some predictive obesity variables in Wistar rats (90 days), up to the 14th day of pregnancy: control non-pregnant (N = 5) and pregnant (N = 7) groups (control diet: 17% protein), and low-protein non-pregnant (N = 5) and pregnant (N = 6) groups (low-protein diet: 6%). Independent of the protein content of the diet, pregnancy increased total (F1,19 = 22.28, P < 0.001) and relative (F1,19 = 5.57, P < 0.03) food intake, the variation of weight (F1,19 = 49.79, P < 0.000) and final body weight (F1,19 = 19.52, P...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Low-protein diet; Pregnancy; Serum leptin; Serum insulin; Body adiposity.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000600014
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Cuidados com fêmeas caprinas durante a prenhez e o parto. Infoteca-e
SILVA, E. R. da.
bitstream/item/26719/1/COT-54.pdf
Tipo: Comunicado Técnico (INFOTECA-E) Palavras-chave: Manejo reprodutivo; Brasil; Ceará; Caprino; Reprodução animal; Prenhez; Parto; Goats; Reproduction; Pregnancy; Parturition.
Ano: 1999 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/515275
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Determinação da idade gestacional em caprinos com base nas dimensões embrionárias. Repositório Alice
SOARES, A. T.; SALLES, H. O.; MOURA SOBRINHO, P. A.; AZEVEDO, H. C..
Tipo: Anais e Proceedings de eventos Palavras-chave: Ultrasonografia transretal; Transrectal ultrasound; Growth.; Animal embryos; Ultra-Som; Caprino; Cabra; Prenhez; Reprodução animal; Embrião; Crescimento.; Goats; Animal reproduction; Pregnancy; Ultrasonography..
Ano: 1997 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/514851
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Differential expression of microRNA-411 and 376c is associated with hypertension in pregnancy BJMBR
Yang,Hui-li; Zhang,Hong-zhi; Meng,Fan-rong; Han,Shu-yi; Zhang,Miao.
Preeclampsia is a major reason of morbidity and mortality in pregnant women and perinatal fetus. Hence, it is of prime importance that diagnostic markers are defined to predict chances of preeclampsia in pregnant women. It has been previously shown that microRNA (miRNA)-376c expression is decreased in the placenta of preeclampsia patients at term. Even though this decrease was not mimicked in the placenta at the pre-term stage, miR-376c expression was decreased in the plasma of these patients as early as the second trimester. Plasma and placenta specimens were obtained from pregnant women having unifetal gestation undergoing perinatal care between January 2014 and December 2016 (n=49). Early trimester placentas were collected from patients undergoing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Preeclampsia; Pregnancy; Hypertension; MiR-411; MiR-376c.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000400607
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Disruption of reproductive development in male rat offspring following gestational and lactational exposure to di-(2-ethylhexyl) phthalate and genistein Biol. Res.
Zhang,Lian-Dong; Deng,Qian; Wang,Zi-Ming; Gao,Ming; Wang,Lei; Chong,Tie; Li,He-Cheng.
Studies of developmental effects of mixtures of endocrine disrupters on the male reproductive system are of great concern. In this study, the reproductive effects of the co-administration of di-2-(ethylhexyl) phthalate (DEHP) and genistein (GEN) during pregnancy and lactation were studied in male rat offspring. Pregnant Sprague-Dawley rats were gavaged from gestation day 3 to postnatal day 21 with vehicle control, DEHP 250 mg/kg body weight (bwyday, GEN 50 mg/kg bwday, GEN 400 mg/kg bwday, and two combinations of the two compounds (DEHP 250 mg/kg bwday + GEN 50 mg/kg bwday, DEHP 250 mg/kg bwday + GEN 400 mg/kg bwday). The outcomes studied were general morphometry (weight, AGD), testicular histology, testosterone levels, and expression at the mRNA level of...
Tipo: Journal article Palavras-chave: Di-2-(ethylhexyl) phthalate; Genistein; Pregnancy; Lactation; Reproductive system.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000200004
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