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| Registros recuperados: 17 | |
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| LIXA,CAROLINA; MUJO,AMANDA; ANOBOM,CRISTIANE D.; PINHEIRO,ANDERSON S.. |
| Bacteria are able to synchronize the population behavior in order to regulate gene expression through a cell-to-cell communication mechanism called quorum sensing. This phenomenon involves the production, detection and the response to extracellular signaling molecules named autoinducers, which directly or indirectly regulate gene expression in a cell density-dependent manner. Quorum sensing may control a wide range of biological processes in bacteria, such as bioluminescence, virulence factor production, biofilm formation and antibiotic resistance. The autoinducers are recognized by specific receptors that can either be membrane-bound histidine kinase receptors, which work by activating cognate cytoplasmic response regulators, or cytoplasmic receptors... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Autoinducer; Bacteria; Quorum sensing; Receptor; Structure. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502189 |
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| Siciliano,Florencia; Torres,Pablo; Sendín,Lorena; Bermejo,Carolina; Filippone,Paula; Vellice,Gabriel; Ramallo,Jackie; Castagnaro,Atilio; Vojnov,Adrian; Marano,María Rosa. |
| Xanthomonas axonopodis pathovar citri (Xac) causes bacterial citrus canker, a serious disease of most citrus species. Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot disease in cruciferous plants. In Xcc, cell-cell signaling is mediated by diffusible signal factor (DSF). Synthesis of DSF depends on RpfB and RpfF. DSF perception and signal transduction have been suggested to involve a two-component system comprising RpfC and RpfG. It has been proposed that these proteins participate in a signal transduction system linking changes in the environment to the synthesis of DSF and the expression of virulence genes. Although the cluster of the rpf genes in Xac has synteny with the corresponding cluster in Xcc, two genes (rpfH and... |
| Tipo: Journal article |
Palavras-chave: Canker; DSF; Extracellular polysaccharide; Quorum sensing. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582006000300005 |
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| RODRIGUES,Adeline Conceição; OLIVEIRA,Brígida D’Ávila de; SILVA,Elis Regina da; SACRAMENTO,Nayara Thais Barbosa; BERTOLDI,Michele Corrêa; PINTO,Uelinton Manoel. |
| Abstract The aim of this study was to assess the anti-quorum sensing activity of phenolic extracts from grumixama (Eugenia brasiliensis), also known as Brazilian cherry, in concentrations that did not interfere with bacterial growth. The pulp phenolic compounds were extracted by using solid phage extraction in a mini-collumn C18 and quantified by spectrophotometry. The anti-quorum sensing activity was evaluated by testing the inhibition of violacein production in Chromobacterium violaceum and by evaluating the swarming motility in Aeromonas hydrophila and Serratia marcescens, both phenotypes regulated by quorum sensing. The phenolic extract strongly inhibited the production of violacein in C. violaceum, reducing its production in comparison with a control... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Quorum sensing; Anti-quorum sensing; Phenolic extract; Brazilian cherry; Eugenia brasiliensis. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612016000200337 |
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| Doberva, Margot; Sanchez-ferandin, Sophie; Toulza, Eve; Lebaron, Philippe; Lami, Raphael. |
| Quorum sensing (QS) is a cell-to-cell signalling pathway that allows bacteria to synchronize their genetic expression. It is mediated by autoinducers (AI), including (1) acyl-homoserine lactones (AHLs or AI-1), produced by Proteobacteria using AinS, LuxI and HdtS synthase families and (2) furanosyl-diester-borate (FDB or AI-2), produced by a large range of phylogenetically diverse bacteria and synthetized by the LuxS family. Few data have been collected about the presence and importance of QS in marine waters using culture independent methods. In this study, we examined the presence and the diversity of AI-1 and AI-2 synthases in the Global Ocean Sampling (GOS), a large metagenomic database, covering 68 stations across 3 oceans. We built 4 reference... |
| Tipo: Text |
Palavras-chave: Quorum sensing; Acyl-homoserine lactone synthases; Global Ocean Sampling; Environmental metagenomes. |
| Ano: 2015 |
URL: https://archimer.ifremer.fr/doc/00615/72718/71710.pdf |
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| Muñoz Cazares, Naybi Rosario. |
| La comunicación bacteriana o censado de quórum, es un proceso de expresión de genes a nivel poblacional, dependiente de la densidad bacteriana y mediado por moléculas llamadas autoinductoras, que regula entre otros fenotipos, la expresión de los factores de virulencia. La inhibición del sistema de censado de quórum (I-SCQ), se considera un nuevo blanco, con mecanismo de acción distinto al de los antibióticos. El objetivo de este proyecto, consistió en realizar un estudio biodirigido de la actividad I-SCQ de las cortezas de Amphypterygium adstringens, Ceiba pentandra y Ceiba aesculifolia, empleando el modelo de inhibición de violaceína en Chromobacterium violaceum. Los resultados obtenidos, indican la presencia de fracciones activas para las tres cortezas,... |
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Palavras-chave: Comunicación bacteriana; Censado de quórum bacteriano; Amphipterygium adstringens; Ceiba aesculifolia; Ceiba pentandra; Anti-censado de quórum; Plantas anti-quórum; Bacterial communication; Quorum sensing; Anti-quorum sensing; Anti-quorum plants; Botánica; Maestría. |
| Ano: 2013 |
URL: http://hdl.handle.net/10521/2081 |
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| De Decker, Sophie; Reynaud, Yann; Saulnier, Denis. |
| The aim of that studywas to explore the hypothesis that a quorumsensingmechanismmodulatesmetalloprotease gene expression of two Vibrio species pathogenic for oyster, at intraspecific (Vibrio splendidus) and interspecific (V. splendidus affecting V. aestuarianus) levels. Metalloprotease activities (Vsm for V. splendidus LGP32 and Vam for V. aestuarianus 02/041) and growth curves obtained by real-time PCR assay revealed cell density-dependent metalloprotease inductions triggered between 12 h and 16 h of culture. A quorum sensing assay was then developed using a conditioned medium prepared from supernatant of a mutant strain of V. splendidus LGP32 unable to produce metalloprotease. Specific real-time qPCR assays targeting metalloprotease genes vsm and vam... |
| Tipo: Text |
Palavras-chave: Quorum sensing; Crassostrea gigas; Vibrio; Metalloprotease; Gene expression. |
| Ano: 2013 |
URL: http://archimer.ifremer.fr/doc/00124/23539/21381.pdf |
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| Conceição,Rita de Cássia dos Santos da; Sturbelle,Régis Tuchtenhagen; Timm,Cláudio Dias; Leite,Fábio Pereira Leivas. |
| Genus Salmonella bacteria are among the major pathogenic microorganisms in food. This bacterium pathogenicity is related to a number of virulence factors, among which its flagella. Flagellum expression is one of the virulence factors modulated by Quorum Sensing. Epinephrine produced by mammals uses the same signaling pathway of the 3 bacteria autoinducer. This study evaluated the effect of molecules inducer (epinephrine) and autoinducers (autoinducer 2 and autoinducer 3) and their association with the motility, growth and expression genes flhC, fliA, fliY, motA, motB e fliC of Salmonella Typhimurium (ST). Initially, ST was inoculated in BHI. Then, motility assays, growth curves and gene expression were performed by testing different concentrations of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Quorum sensing; Salmonella; Epinephrine; Autoinducer; Motility. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001202201 |
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| Martins,Maurilio L.; Uelinton,M. Pinto; Riedel,Kathrin; Vanetti,Maria C.D.; Mantovani,Hilário C.; Araújo,Elza F. de. |
| Numerous bacteria coordinate gene expression in response to small signalling molecules in many cases known as acylhomoserine lactones (AHLs), which accumulate as a function of cell density in a process known as quorum sensing. This work aimed to determine if phenotypes that are important to define microbial activity in foods such as biofilm formation, swarming motility and proteolytic activity of two Pseudomonas fluorescens strains, isolated from refrigerated raw milk, are influenced by AHL molecules. The tested P. fluorescens strains did not produce AHL molecules in none of the evaluated media. We found that biofilm formation was dependent on the culture media, but it was not influenced by AHLs. Our results indicate that biofilm formation, swarming... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Milk; Pseudomonas fluorescens; Biofilm formation; Quorum sensing; Quorum quenching. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300037 |
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| Vadstein, Olav; Bergh, Oivind; Gatesoupe, Joel; Galindo-villegas, Jorge; Mulero, Victoriano; Picchietti, Simona; Scapigliati, Giuseppe; Makridis, Pavlos; Olsen, Yngvar; Dierckens, Kristof; Defoirdt, Tom; Boon, Nico; De Schryver, Peter; Bossier, Peter. |
| For most marine aquaculture species, one of the main bottlenecks is the stable production of high quality juveniles. The high and unpredictable mortality in the first weeks after hatching of marine fish larvae remains a challenging problem that needs to be solved. The severity of the problem differs between species, but cannot be considered adequately solved for any species. Both scientific evidence and experience in hatcheries for a variety of fish, shrimp and shellfish species are accumulating as support for the hypothesis that detrimental fish-microbe interactions are the cause of these problems. Host-microbe interactions in reared fish are still poorly understood, except for a few pathogens, and empirical data of the quality required to test this... |
| Tipo: Text |
Palavras-chave: Host-microbe interaction; Mast cell; Microbial ecology; Piscidin; Quorum sensing. |
| Ano: 2013 |
URL: http://archimer.ifremer.fr/doc/00144/25510/23654.pdf |
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| Mai, T.; Tintillier, Florent; Lucasson, Aude; Moriou, C.; Bonno, E.; Petek, S.; Magre, Kevin; Al Mourabit, A.; Saulnier, Denis; Debitus, C.. |
| Sponges are a rich source for investigation of bioactive small molecules. They have been mostly investigated for the search of new pharmacological models or therapeutic agents for the treatment of human diseases. Micro-organisms can also represent a virulent pathogen for marine invertebrates such as sponges, which need to protect themselves against these microbes. Sponges' self defence mechanisms involving dialogue molecules thus represent a pertinent research track for potent anti-infective and anti-biofilm activities such as quorum sensing inhibitors (QSIs). The investigation of the QSI crude extract of Leucetta chagosensis Dendy, 1863 led to the isolation of three new alkaloids, isonaamine D, di-isonaamidine A and leucettamine D, along with the known... |
| Tipo: Text |
Palavras-chave: Biofouling; Leucetta chagosensis; Leucettamine; Naamidine; Naamine; Quorum sensing; Quorum sensing inhibitors; Sponges; Vibrio harveyi. |
| Ano: 2015 |
URL: http://archimer.ifremer.fr/doc/00275/38597/37189.pdf |
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| Rodrigues, Sophie; Paillard, Christine; Van Dillen, Sabine; Tahrioui, Ali; Berjeaud, Jean-marc; Dufour, Alain; Bazire, Alexis. |
| Marine pathogenic bacteria are able to form biofilms on many surfaces, such as mollusc shells, and they can wait for the appropriate opportunity to induce their virulence. Vibrio tapetis can develop such biofilms on the inner surface of shells of the Ruditapes philippinarum clam, leading to the formation of a brown conchiolin deposit in the form of a ring, hence the name of the disease: Brown Ring Disease. The virulence of V. tapetis is presumed to be related to its capacity to form biofilms, but the link has never been clearly established at the physiological or genetic level. In the present study, we used RNA-seq analysis to identify biofilm- and virulence-related genes displaying altered expression in biofilms compared to the planktonic condition. A... |
| Tipo: Text |
Palavras-chave: Biofilm; Virulence; Vibrio tapetis; Transcriptome; Quorum sensing; Type VI secretion system; Brown ring disease. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00470/58140/60611.pdf |
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| Le Norcy, Tiffany; Niemann, Hendrik; Proksch, Peter; Tait, Karen; Linossier, Isabelle; Rehel, Karine; Hellio, Claire; Fay, Fabienne. |
| Since the banning of several families of compounds in antifouling (AF) coatings, the search for environmentally friendly AF compounds has intensified. Natural sources of AF compounds have been identified in marine organisms and can be used to create analogues in laboratory. In a previous study, we identified that dibromohemibastadin-1 (DBHB) is a promising AF molecule, leading to the inhibition of the activity of phenoloxidase, an enzyme involved in the attachment of mussels to surfaces. This paper describes the activity of the DBHB on biofilm formation and its detachment and on bacterial adhesion and communication: quorum sensing. DBHB has an anti-biofilm activity without affecting adhesion of marine and terrestrial bacteria at a dose of 10 mu M.... |
| Tipo: Text |
Palavras-chave: Biofouling; Biofilm; Bastadin derivative; Microfouling; Quorum sensing; Sponge. |
| Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00616/72813/72581.pdf |
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| Registros recuperados: 17 | |
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