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| Registros recuperados: 33 | |
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| Blanc, Mélanie; Alfonso, Sebastien; Bégout, Marie-laure; Barrachina, Célia; Hyötyläinen, Tuulia; Keiter, Steffen H.; Cousin, Xavier. |
| Polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) are persistent organic pollutants still present in aquatic environments despite their total or partial ban. Previously, we observed that an environmentally realistic mixture of these compounds affects energy balance, growth, and reproduction in exposed zebrafish (F0), and behavior in their unexposed offspring (F1-F4). In the present work, we performed lipidomic and transcriptomic analyses on brains of zebrafish (F0-F2) from exposed and control lineages to identify molecular changes that could explain the observed phenotypes. The use of both technologies highlighted that F0 zebrafish displayed impaired mitochondrial function and lipid metabolism regulation (depletion in... |
| Tipo: Text |
Palavras-chave: Danio rerio; Persistent-organic pollutant; Neurotoxicity; Brain metabolism; RNA-Seq. |
| Ano: 2021 |
URL: https://archimer.ifremer.fr/doc/00646/75797/76720.pdf |
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| IBELLI, A. M. G.; PEIXOTO, J. de O.; SAVOLDI, I. R.; CARMO, K. B. do; MORES, N.; MORES, M. A. Z.; CANTAO, M. E.; COUTINHO, L. L.; LEDUR, M. C.. |
| Abstract: The articular osteochondrosis (OC) is a disturbance of endochondral ossification occurring in humans and livestock animals. In pigs, OC is one of the major causes of leg weakness, leading to economic losses and reducing the animal welfare. The aim of this study was to evaluate the differential gene expression related to OC latens in femoral articular cartilage in swine. Thus, samples of MS115 5-months-old gilts, normal (control group) and affected with OC latens (affected group), were collected and submitted to histopathological and gene expression analysis. A total of 1,734 genes was differentially expressed (DE) between the two groups. Several biological processes (BP) were enriched including those already known as involved with OC, such as... |
| Tipo: Separatas |
Palavras-chave: Desenvolvimento ósseo; Características do fêmur; Osteocondrose articular; Problemas de locomoção; Locomotor problems; RNA-Seq; Melhoramento Genético Animal; Suíno; Gene; Osso; Fêmur; Animal genetic resources; Swine; Osteochondrosis; Gene expression; Lameness; Leg weakness. |
| Ano: 2018 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1093227 |
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| Zhou,Qin; Wang,Aidong; Duan,Ruijun; Yan,Jun; Zhao,Gang; Nevo,Eviatar; Chen,Guoxiong. |
| Abstract The naturally occurring wild barley mutant eibi1/hvabcg31 suffers from severe water loss due to the permeable leaf cuticle. Eibi1/HvABCG31 encodes a full ATP-binding cassette (ABC) transporter, HvABCG31, playing a role in cutin deposition in the elongation zone of growing barley leaves. The eibi1 allele has pleiotropic effects on the appearance of leaves, plant stature, fertility, spike and grain size, and rate of germination. Comparative transcriptome profile of the leaf elongation zone of the eibi1 mutant as well as its isogenic wild type showed that various pathogenesis-related genes were up-regulated in the eibi1 mutant. The known cuticle-related genes that we analyzed did not show significant expression difference between the mutant and wild... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ABC transporter; Defense genes; Desiccation tolerance; Plant cuticle; RNA-Seq. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000500834 |
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| Harney, Ewan; Dubief, Bruno; Boudry, Pierre; Basuyaux, Olivier; Schilhabel, Markus B.; Huchette, Sylvain; Paillard, Christine; Nunes, Flavia. |
| The European abalone Haliotis tuberculata is a delicacy and consequently a commercially valuable gastropod species. Aquaculture production and wild populations are subjected to multiple climate-associated stressors and anthropogenic pressures, including rising sea-surface temperatures, ocean acidification and an emerging pathogenic Vibrio infection. Transcript expression data provides a valuable resource for understanding abalone responses to variation in the biotic and abiotic environment. To generate an extensive transcriptome, we performed next-generation sequencing of RNA on larvae exposed to temperature and pH variation and on haemolymph of adults from two wild populations after experimental infection with Vibrio harveyi. We obtained more than 1.5... |
| Tipo: Text |
Palavras-chave: RNA-Seq; Mollusca; Gastropoda; Development; Vibrio harveyi; Climate change. |
| Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00318/42940/45103.pdf |
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| PEIXOTO, J. de O.; IBELLI, A. M. G.; CANTAO, M. E.; ZANELLA, R.; JAENISCH, F. R. F.; GIACHETTO, P. F.; SETTLES, M. L.; PANDOLFI, J. R. C.; COUTINHO, L. L.; LEDUR, M. C.. |
| Resumo: A incidência de problemas ósseos é considerada uma das principais preocupações para a indústria avícola devido à perdas econômicas significativas e ao impacto negativo no bem-estar. As vias metabólicas e os genes envolvidos nas patologias ósseas permanecem desconhecidos. A condronecrose bacteriana com osteomielite (BCO) é uma das principais doenças ligadas a problemas locomotores em frangos. Na tentativa de esclarecer os mecanismos genéticos envolvidos na manifestação da BCO, objetivou-se identificar os genes diferencialmente expressos no fêmur de frangos de corte normais e afetados por esta desordem, por meio da tecnologia de RNA-Seq. Neste estudo foram utilizados frangos de corte comerciais machos aos 35 dias de idade sendo 4 normais e 4 com BCO... |
| Tipo: Anais e Proceedings de eventos |
Palavras-chave: BCO; Differentially expressed genes; RNA-Seq; Bacterial Chondronecrosis with Osteomyelitis; Patologia óssea; Ontologia gênica.; Genes.. |
| Ano: 2015 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1024034 |
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| GIACHETTO, P. F.; CUNHA, R. C.; NHANI JUNIOR, A.; GARCIA, M. V.; FERRO, J. A.; ANDREOTTI, R.. |
| The success of cattle tick fixation largely depends on the secretion of substances that alter the immune response of the host. The majority of these substances are expressed by the parasite salivary gland and secreted in tick saliva. It is known that hosts can mount immune responses against ticks and bovine European breeds, and bovine industrial crossbreeds are more susceptible to infestations than are Bos indicus cattle. To identify candidates for the development of novel control strategies for the cattle tick Rhipicephalus (Boophilus) microplus, a salivary gland transcriptome analysis of engorged females fed on susceptible or resistant hosts was performed. Using RNA-Seq, transcriptomes were de novo assembled and produced a total of 235,451 contigs with... |
| Tipo: Artigo de periódico |
Palavras-chave: Bioinformática; Expressão gênica; RNA-Seq; Cattle tick; Host-parasite interaction; Gado de Corte; Carrapato; Sialome; Transcriptome; Cattle; Bioinformatics; Rhipicephalus microplus. |
| Ano: 2020 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1124241 |
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| GIACHETTO, P. F.; CUNHA, R. C.; NHANI JUNIOR, A.; GARCIA, M. V.; FERRO, J. A.; ANDREOTTI, R.. |
| The success of cattle tick fixation largely depends on the secretion of substances that alter the immune response of the host. The majority of these substances are expressed by the parasite salivary gland and secreted in tick saliva. It is known that hosts can mount immune responses against ticks and bovine European breeds, and bovine industrial crossbreeds are more susceptible to infestations than are Bos indicus cattle. To identify candidates for the development of novel control strategies for the cattle tick Rhipicephalus (Boophilus) microplus, a salivary gland transcriptome analysis of engorged females fed on susceptible or resistant hosts was performed. Using RNA-Seq, transcriptomes were de novo assembled and produced a total of 235,451 contigs with... |
| Tipo: Artigo de periódico |
Palavras-chave: RNA-Seq; Cattle tick; Host-parasite interaction; Sialome; Transcriptome; Cattle. |
| Ano: 2020 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1119455 |
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| CASASSOLA, A.; BRAMMER, S. P.; CHAVES, M. S.; NHANI JUNIOR, A.; MARTINELLI, J. A.; KUSER-FALCAO, P. R.; ZERLOTINI, A.; GRANDO, M. F.; STEFANATO, F.; BOYD, L.. |
| Orientadora: Sandra Patussi Brammer. |
| Tipo: Parte de livro |
Palavras-chave: Ferrugem da folha; RNA-Seq; Expressão diferencial. |
| Ano: 2015 |
URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1018075 |
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| Liu,Tianxiang; Li,Huiru; Ding,Yatong; Qi,Yuancheng; Gao,Yuqian; Song,Andong; Shen,Jinwen; Qiu,Liyou. |
| Abstract Dikarya is a subkingdom of fungi that includes Ascomycota and Basidiomycota. The gene expression patterns of dikaryon are poorly understood. In this study, we bred a dikaryon DK13 × 3 by mating monokaryons MK13 and MK3, which were from the basidiospores of Pleurotus ostreatus TD300. Using RNA-Seq, we obtained the transcriptomes of the three strains. We found that the total transcript numbers in the transcriptomes of the three strains were all more than ten thousand, and the expression profile in DK13 × 3 was more similar to MK13 than MK3. However, the genes involved in macromolecule utilization, cellular material synthesis, stress-resistance and signal transduction were much more up-regulated in the dikaryon than its constituent monokaryons. All... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Differential gene expression; Monoallelic expression; Monokaryon; RNA editing; RNA-Seq. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200380 |
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| Registros recuperados: 33 | |
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