Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Ordenar por: 

RelevânciaAutorTítuloAnoImprime registros no formato resumido
Registros recuperados: 9
Primeira ... 1 ... Última
Imagem não selecionada

Imprime registro no formato completo
A novel polymorphism in the coding region of the vasopressin type 2 receptor gene BJMBR
Nephrogenic diabetes insipidus (NDI) is a rare disease characterized by renal inability to respond properly to arginine vasopressin due to mutations in the vasopressin type 2 receptor (V2(R)) gene in affected kindreds. In most kindreds thus far reported, the mode of inheritance follows an X chromosome-linked recessive pattern although autosomal-dominant and autosomal-recessive modes of inheritance have also been described. Studies demonstrating mutations in the V2(R) gene in affected kindreds that modify the receptor structure, resulting in a dys- or nonfunctional receptor have been described, but phenotypically indistinguishable NDI patients with a structurally normal V2(R) gene have also been reported. In the present study, we analyzed exon 3 of the...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Vasopressin; Receptor; Polymorphism; Diabetes insipidus; Receptor gene polymorphism.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000400002
Imagem não selecionada

Imprime registro no formato completo
A receptor for infectious and cellular prion protein BJMBR
Martins,V.R..
Prions are an unconventional form of infectious agents composed only of protein and involved in transmissible spongiform encephalopathies in humans and animals. The infectious particle is composed by PrPsc which is an isoform of a normal cellular glycosyl-phosphatidylinositol (GPI) anchored protein, PrPc, of unknown function. The two proteins differ only in conformation, PrPc is composed of 40% <FONT FACE="Symbol">a</FONT> helix while PrPsc has 60% ß-sheet and 20% <FONT FACE="Symbol">a</FONT> helix structure. The infection mechanism is trigged by interaction of PrPsc with cellular prion protein causing conversion of the latter's conformation. Therefore, the infection spreads because new PrPsc molecules are generated exponentially...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Prion; Transmissible spongiform encephalopathies; PrPc; Receptor.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000700009
Imagem não selecionada

Imprime registro no formato completo
A structural perspective on the mechanisms of quorum sensing activation in bacteria Anais da ABC (AABC)
LIXA,CAROLINA; MUJO,AMANDA; ANOBOM,CRISTIANE D.; PINHEIRO,ANDERSON S..
Bacteria are able to synchronize the population behavior in order to regulate gene expression through a cell-to-cell communication mechanism called quorum sensing. This phenomenon involves the production, detection and the response to extracellular signaling molecules named autoinducers, which directly or indirectly regulate gene expression in a cell density-dependent manner. Quorum sensing may control a wide range of biological processes in bacteria, such as bioluminescence, virulence factor production, biofilm formation and antibiotic resistance. The autoinducers are recognized by specific receptors that can either be membrane-bound histidine kinase receptors, which work by activating cognate cytoplasmic response regulators, or cytoplasmic receptors...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autoinducer; Bacteria; Quorum sensing; Receptor; Structure.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502189
Imagem não selecionada

Imprime registro no formato completo
Differences in progesterone concentrations and mRNA expressions of progesterone receptors in bovine endometrial tissue between the uterine horns ipsilateral and contralateral to the corpus luteum OAK
TAKAHASHI, Hiroto; HANEDA, Shingo; KAYANO, Mitsunori; MATSUI, Motozumi; 羽田, 真悟; 茅野, 光範; 松井, 基純.
Because the establishment of pregnancy begins at the uterine horn ipsilateral to the corpus luteum (ipsi-horn) in cattle, levels of progesterone (P4) and receptor expression in the endometrial tissue, which regulate the intrauterine environment for embryo development, may differ between the ipsi-horn and the uterine horn contralateral to corpus luteum (contra-horn). The aim of the present study was to determine the endometrial tissue P4 concentrations and nuclear progesterone receptor (PGR), progesterone receptor membrane component 1 (PGRMC1) and PGRMC2 mRNA expressions in the cranial and middle parts of the uterine horns during the luteal phase. The results showed higher endometrial tissue P4 concentrations in the cranial part of the ipsi-horn than in...
Palavras-chave: Bovine; Progesterone; Receptor; Uterus.
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4364
Imagem não selecionada

Imprime registro no formato completo
Functionomics: the analysis of a postgenomic concept on the basis of pregenomic pharmacological studies in smooth muscle Anais da ABC (AABC)
Jurkiewicz,Aron; Caricati-Neto,Afonso; Jurkiewicz,Neide H..
The term functionomics (Amin 2003, Neumann et al. 2004) refers to a postgenomic integrated Systems Biology (Attur et al. 2002) using a multidimensional approach for cells, tissues and organs. It considers current or future involvement among genomics, proteomics or metabolomics, including the main factors that cause biological responses and modulation under different conditions. Our objective in the present review is to summarize the contemporary understanding of functionomics of smooth muscle pharmacology, based on the results obtained on the pregenomic era during several years in our laboratory. The present approach is based on the knowledge of the dynamics of the receptor system, which comprises a cascade of phenomena, leading from the drug...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Functionomics; Receptor; Smooth muscle; Genomic.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300022
Imagem não selecionada

Imprime registro no formato completo
Histologic distribution of insulin and glucagon receptors BJMBR
Watanabe,M.; Hayasaki,H.; Tamayama,T.; Shimada,M..
Insulin and glucagon are the hormonal polypeptides secreted by the B and A cells of the endocrine pancreas, respectively. Their major physiologic effects are regulation of carbohydrate metabolism, but they have opposite effects. Insulin and glucagon have various physiologic roles, in addition to the regulation of carbohydrate metabolism. The physiologic effects of insulin and glucagon on the cell are initiated by the binding of each hormone to receptors on the target cells. Morphologic studies may be useful for relating biochemical, physiologic, and pharmacologic information on the receptors to an anatomic background. Receptor radioautography techniques using radioligands to label specific insulin and glucagon receptors have been successfully applied to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Radioautography; Insulin; Glucagon; Receptor; Distribution.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000200008
Imagem não selecionada

Imprime registro no formato completo
Receptor expression and responsiveness of human peripheral blood mononuclear cells to a human cytomegalovirus encoded CC chemokine BJID
Zheng,Qi; Xu,Jun; Gao,Huihui; Tao,Ran; Li,Wei; Shang,Shiqiang; Gu,Weizhong.
Human cytomegalovirus is a ubiquitous pathogen that infects the majority of the world's population. After long period of time co-evolving with human being, this pathogen has developed several strategies to evade host immune surveillance. One of the major trick is encoding homologous to those of the host organism or stealing host cellular genes that have significant functions in immune system. To date, we have found several viral immune analogous which include G protein coupled receptor, class I major histocompatibility complex and chemokine. Chemokine is a small group of molecules which is defined by the presence of four cysteines in highly conserved region. The four kinds of chemokines (C, CC, CXC, and CX3C) are classified based on the arrangement of 1 or 2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chemokine; Cytomegalovirus; Receptor; Immune.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400403
Imagem não selecionada

Imprime registro no formato completo
The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors BJMBR
Machado,L.J.C.; Marubayashi,U.; Reis,A.M.; Coimbra,C.C..
We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were designed to determine the participation of AT1 receptors in the hyperglycemic action of angiotensin II in freely moving rats. The animals were divided into two experimental groups: 1) animals submitted to intravenous administration of angiotensin II (0.96 nmol/100 g body weight) which caused a rapid increase in plasma glucose reaching the highest values at 5 min after the injection (33% of the initial values, P&lt;0.01), and 2) animals submitted to intravenous administration of DuP-753 (losartan), a...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Glycemia; Angiotensin II; DuP-753; AT1; Receptor.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001000018
Imagem não selecionada

Imprime registro no formato completo
Unraveling the signaling and signal transduction mechanisms controlling arbuscular mycorrhiza development Scientia Agricola
Lambais,Marcio Rodrigues.
Arbuscular mycorrhiza (AM) are the most widespread symbiotic associations between plant roots and soil fungi. AM can contribute to increasing the survival and fitness of plants to limiting environments mostly due to their ability in improving nutrient uptake from the soil solution. Despite their ecological significance, the mechanisms controlling AM development and functioning are largely unknown. The obligate mutualistic nature of the arbuscular mycorrhizal fungi (AMF) has hampered the advances on the understanding and application of the symbiosis. Significant alterations in the genetic programs of both symbionts are required for the successful establishment of an AM, and complex signaling and signal transduction mechanisms are likely involved. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: DMI gene; Symbiosis; Branching factor; Receptor; Calcium spiking.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162006000400013
Registros recuperados: 9
Primeira ... 1 ... Última
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional