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	Provedor de dados BJMBR (2) Autor Cabral,A.M. (1) Fazan Jr.,R. (1) Futuro Neto,H.A. (1) Macedo,S.M. (1) Machado,B.H. (1) Pires,J.G.P. (1) Salgado,H.C. (1) Silva,N.F. (1) Mais... Palavra-chave Reflex bradycardia (2) 5-HT2 receptors (1) Aortic coarctation (1) Aortic resistance (1) Doppler flowmetry (1) Hypertension (1) R-96544 (1) SB-204741 (1) Sinoaortic denervation (1) Vagal motoneurons (1) Von Bezold-Jarisch reflex (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 1997 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Central 5-HT2A receptors modulate the vagal bradycardia in response to activation of the von Bezold-Jarisch reflex in anesthetized rats BJMBR Futuro Neto,H.A.; Macedo,S.M.; Silva,N.F.; Cabral,A.M.; Pires,J.G.P.. Activation of 5-hydroxytryptamine (5-HT) 5-HT1A, 5-HT2C, 5-HT3, and 5-HT7 receptors modulates the excitability of cardiac vagal motoneurones, but the precise role of 5-HT2A/2B receptors in these phenomena is unclear. We report here the effects of intracisternal (ic) administration of selective 5-HT2A/2B antagonists on the vagal bradycardia elicited by activation of the von Bezold-Jarisch reflex with phenylbiguanide. The experiments were performed on urethane-anesthetized male Wistar rats (250-270 g, N = 7-9 per group). The animals were placed in a stereotaxic frame and their atlanto-occipital membrane was exposed to allow ic injections. The rats received atenolol (1 mg/kg, iv) to block the sympathetic component of the reflex bradycardia; 20-min later, the... Tipo: Info:eu-repo/semantics/article Palavras-chave: 5-HT2 receptors; R-96544; Reflex bradycardia; SB-204741; Vagal motoneurons; Von Bezold-Jarisch reflex. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300008 Hemodynamic responses to acute aortic coarctation in conscious sinoaortic denervated rats BJMBR Fazan Jr.,R.; Machado,B.H.; Salgado,H.C.. The hemodynamic responses to acute (45 min) partial aortic constriction were studied in conscious intact (N = 7) or sinoaortic denervated (SAD) adult male Wistar rats (280-350 g, N = 7) implanted with carotid and femoral arterial catheters, a pneumatic cuff around the abdominal aorta and a pulsed Doppler flow probe to measure changes in aortic resistance. In addition, the hypertensive response and the reflex bradycardia elicited by total (N = 8) vs partial (N = 7) aortic constriction (monitored by maintenance of the pressure distal to the cuff at 50 mmHg) were compared in two other groups of intact rats. Intact rats presented a smaller hypertensive response (26 to 40% above basal level) to partial aortic constriction than SAD rats (38 to 58%). The... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypertension; Aortic coarctation; Doppler flowmetry; Aortic resistance; Reflex bradycardia; Sinoaortic denervation. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000018 Registros recuperados: 2 Primeira ... 1 ... Última

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