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| Registros recuperados: 27 | |
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| Lecuit, M.; Sonnenburg, J. L.; Cossart, P.; Gordon, J. I.. |
| Members of the genus Listeria provide a model for defining host responses to invasive foodborne enteropathogens. Active translocation of Listeria monocytogenes across the gut epithelial barrier is mediated by interaction of bacterial internalin (InlA) and its species-specific host receptor, E-cadherin, whereas translocation across Peyer’s patches through M-cells is InlA independent. To define microbial determinants and molecular correlates of the host response to translocation via these two routes, we colonized germ-free transgenic mice expressing the human enterocyte-associated E-cadherin receptor with wildtype (WT) or mutant L. monocytogenes strains, or its nonpathogenic noninvasive relative Listeria innocua, or with Bacteroides thetaiotaomicron, a... |
| Tipo: Journal Article |
Palavras-chave: LISTERIA MONOCYTOGENES; CADHERINE; BARRIERE INTESTINALE; LAMINA PROPRIA; PROTEINE BACTERIENNE; INTESTIN; MODELE ANIMAL; SOURIS; INFECTION; ENTEROPATHOGENE; MUTATION; EXPRESSION DES GENES; REPONSE IMMUNITAIRE; IMMUNITE. |
| Ano: 2007 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD200924d16b14&uri=/notices/prodinra1/2010/11/ |
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| Schibler, L.; Roig, A.; MAHE (Collaborateur); Laurent, P.; Hayes, H.; Rodolphe, F.; Cribiu, E.. |
| Background: Comparative mapping provides new insights into the evolutionary history ofgenomes. In particular, recent studies in mammals have suggested a role for segmental duplicationin genome evolution. In some species such as Drosophila or maize, transposable elements (TEs)have been shown to be involved in chromosomal rearrangements. In this work, we have exploredthe presence of interspersed repeats in regions of chromosomal rearrangements, using an updatedhigh-resolution integrated comparative map among cattle, man and mouse.Results: The bovine, human and mouse comparative autosomal map has been constructed usingdata from bovine genetic and physical maps and from FISH-mapping studies. We confirm mostprevious results but also reveal some discrepancies. A... |
| Tipo: Journal Article |
Palavras-chave: BOVIN; SOURIS; CARTE COMPAREE; SEQUENCES REPETEES. |
| Ano: 2006 |
URL: http://www.prodinra.inra.fr/prodinra/pinra/doc.xsp?id=PROD2007a6475bf1&uri=/notices/prodinra1/2008/08/ |
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| Registros recuperados: 27 | |
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