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Registros recuperados: 58
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Antifungal activities of tacrolimus in combination with antifungal agents against fluconazole-susceptible and fluconazole-resistant Trichosporon asahii isolates BJID
Kubiça,Thaís Felli; Denardi,Laura Bedin; Azevedo,Maria Isabel; Oliveira,Vanessa; Severo,Luiz Carlos; Santurio,Janio Morais; Alves,Sydney Hartz.
ABSTRACT The antifungal activity of tacrolimus in combination with antifungal agents against different fungal species has been previously reported. Here we report the in vitro interactions between tacrolimus and amphotericin B, fluconazole, itraconazole, and caspofungin against 30 clinical isolates of both fluconazole-susceptible and fluconazole-resistant Trichosporon asahii. For these analyses, we used the broth microdilution method based on the M27-A3 technique and checkerboard microdilution method. Tacrolimus showed no activity against T. asahii strains (minimal inhibitory concentrations, MICs > 64.0 µg mL−1). However, a larger synergistic interaction was observed by the combinations tacrolimus + amphotericin B (96.67%) and tacrolimus + caspofungin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Susceptibility; FK506; Resistance; Synergism.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600539
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Antimicrobial susceptibility of Campylobacter sp strains isolated from calves with and without diarrhea in Minas Gerais state, Brazil BJM
Miranda,Karina Leite; Lage,Andrey Pereira.
The antimicrobial susceptibility of 25 Campylobacter sp strains isolated from calves with and without diarrhea - 7 C. coli, 16 C. fetus and 2 C. jejuni was studied by the disk diffusion method. Eleven antimicrobial agents were tested amikacin, ampicillin, kanamycin, chloramphenicol, erythromycin, gentamicin, neomycin, nitrofurantoin, penicillin G, tetracycline and sulfamethoxazole-trimethoprim. All Campylobacter sp strains were susceptible to amikacin, ampicillin, chloramphenicol, erythromycin, gentamicin, neomycin and nitrofurantoin. Three strains were moderately susceptible to kanamycin (2 C. coli and 1 C. fetus). All the strains were resistant to penicillin G. Two C. fetus strains were moderately susceptible to sulfamethoxazole-trimethoprim and 1 C....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Campylobacter sp; Calf; Diarrhea; Antimicrobial agents; Susceptibility.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000200032
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Associação de moscas-das-frutas (Diptera: Tephritidae) com a "meleira do mamoeiro" (Carica papaya L.) Anais da SEB
Nascimento,Antonio S.; R. Matrangolo,Walter J.; Barbosa,Cristiane J.; Marques,Oton M.; Habibe,Tuffi C..
Since 1988, the medfly Ceratitis capitata (Wiedemann) was described infesting papaya (Carica papaya) cv. Sunrise Solo in North of the State of Espírito Santo, Brazil. Two experiments were carried out to determine the infestation of C. capitata and Anastrepha obliqua (Macq.) in papaya fruit, healthy and infected by sticky disease. In the 1st experiment (forced infestation), no infestation of C. capitata in the healthy fruits was observed, and 60.6 pupae/fruit were obtained in the infected fruit. For A. obliqua, the infestation index was 10.3 and 72.4 pupae/fruit for healthy and infected fruit respectively. In the 2nd experiment (inoculated eggs), the infestation index for C. capitata was 4.0 and 6.3 pupae/fruit and for A. obliqua 10.1 and 10.4 pupae/fruit,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Insecta; Ceratitis capitata; Anastrepha obliqua; Host plant; Susceptibility.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0301-80592000000400024
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Association between MCP-1 -2518A>G polymorphism and asthma susceptibility: a meta-analysis BJMBR
Chen,Wenli; Cui,Jiewei; Xiang,Guoan; Zhang,Jianpeng; Gao,Hongmei.
The published data on the association between MCP-1 -2518A>G polymorphism and asthma susceptibility are inconclusive. Therefore, we performed a meta-analysis to estimate the impact of MCP-1 -2518A>G polymorphism on asthma susceptibility. PubMed, Web of Science, Wanfang, and China National Knowledge Infrastructure (CNKI) databases were used to identify eligible studies. The pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were used to calculate the strength of association. Sensitivity analysis was performed to evaluate the influence of individual studies on the estimates of overall effect, and funnel plots and Egger's test were used to assess publication bias. Eight publications with 1562 asthma patients and 1574 controls were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MCP-1; Polymorphism; Asthma; Susceptibility; Meta-analysis.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001100602
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Association between the c.910A>G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population BJMBR
Chen,X.Q.; Wang,F.; Zheng,Y.L.; Fan,Q.X.; Yue,D.L.; Ma,Z.J..
Esophageal cancer (EC) is a common malignancy worldwide. The X-ray repair cross-complementing 1 gene (XRCC1) is one of the most important candidate genes for influencing susceptibility to EC. This study aimed to investigate the effect of XRCC1 genetic variants on susceptibility to EC. A total of 383 EC patients (males: 239, females: 144, mean age: 56.62) and 387 cancer-free controls (males: 251, females: 136, mean age: 58.23) were enrolled in this study. The c.910A>G genetic variant of theXRCC1 gene was determined by polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods. The allele and genotype frequencies indicated statistical differences between EC patients and cancer-free controls. The c.910A>G genetic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Esophageal cancer; XRCC1 gene; Genetic variant; Molecular marker; Susceptibility.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201028
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Association between the g.296596G > A genetic variant of RELN gene and susceptibility to autism in a Chinese Han population Genet. Mol. Biol.
Fu,Xiaoyan; Mei,Zhu; Sun,Lixin.
Autism is a childhood neuro-developmental disorder, and Reelin (RELN) is an important candidate gene for influencing autism. This study aimed at investigating the influence of genetic variants of the RELN gene on autism susceptibility. In this study, 205 autism patients and 210 healthy controls were recruited and the genetic variants of the RELN gene were genotyped by the created restriction site-polymerase chain reaction (CRS-PCR) method. The influence of genetic variants on autism susceptibility was analyzed by association analysis, and the g.296596G > A genetic variant in exon10 of the RELN gene was detected. The frequencies of allele/genotype in autistic patients were significantly different from those in healthy controls, and a statistically...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Autism; Susceptibility; Association analysis; RELN gene; Genetic variants.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400003
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Association of MDR1 gene polymorphisms with the risk of hepatocellular carcinoma in the Chinese Han population BJMBR
Gao,Jian.
The multidrug resistance 1 gene (MDR1) is an important candidate gene for influencing susceptibility to hepatocellular carcinoma (HCC). The objective of the present study was to evaluate the association ofMDR1 polymorphisms with the risk of HCC in the Chinese Han population. A total of 353 HCC patients and 335 healthy subjects were enrolled in the study. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), created restriction site-PCR (CRS-PCR) and DNA sequencing methods were used to identify MDR1 gene polymorphisms. Two allelic variants (c.335T>C and c.3073A>C) were detected. The CC genotype of the c.335T>C polymorphism was associated with an increased risk of developing HCC compared to the TT genotype (OR = 2.161, 95%CI...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatocellular carcinoma; Multidrug resistance 1 gene; Single nucleotide polymorphisms; Susceptibility; Risk factors.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300311
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Associations Between Herbicides and Glyphosate in Agronomic Performance of RR2 Intact Soybean Planta Daninha
CESCO,V.J.S.; ALBRECHT,A.J.P.; RODRIGUES,D.M.; KRENCHINSKI,F.H.; ALBRECHT,L.P..
ABSTRACT: The Roundup Ready (RR) soybean was developed for weed control with the use of glyphosate. Some herbicide combinations with glyphosate has been used in weed control and some effects of this practice may be undesirable in the agronomic performance of RR soybean. The present study evaluated the agronomic performance of RR2 intact soybean applied with associations between herbicides and glyphosate at post-emergence, in two experiments conducted in two municipalities in the state of Paraná, Palotina and Marechal Cândido Rondon. This experiment consisted of seven treatments in a randomized block design with four replications, totaling 28 plots for each municipality. The cultivar used in both experiments was Monsoy 6210 Intact RR2 IPROTM. The variables...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Glycine max; Susceptibility; Selectivity; Phytotoxicity.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582018000100212
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Atividade in vitro do extrato de própolis contra agentes bacterianos da mastite bovina. Repositório Alice
LOGUERCIO, A.P.; GROFF, A.C.M.; PEDROZZO, A.F.; WITT, N.M.; SILVA, M.S. e; VARGAS, A.C. de.
Este trabalho foi desenvolvido com o objetivo de avaliar a atividade in vitro do extrato alcoólico de própolis, contra agentes da mastite bovina, comparando-o aos principais antimicrobianos utilizados no tratamento convencional. Foram utilizados 36 isolados coagulase-positivos de Staphylococcus sp. e 27 isolados de Streptococcus sp.; 94,4% dos Staphylococcus sp. e 85,2% dos Streptococcus sp. foram susceptíveis ao extrato de própolis.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Staphylococcus; Streptococcus; Susceptibilidade; Antimicrobianos; Susceptibility; Antimicrobial.
Ano: 2006 URL: http://www.alice.cnptia.embrapa.br/handle/doc/118458
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Bioassay method for toxicity studies of insecticide formulations to tuta absoluta (meyrick, 1917). Repositório Alice
GALDINO, T. V. da S.; PICANÇO, M. C.; MORAIS, E. G. F. de; SILVA, N. R.; SILVA, G. A. R da; LOPES, M. C..
2011
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Susceptibility.
Ano: 2011 URL: http://www.alice.cnptia.embrapa.br/handle/doc/989094
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Bioassay method for toxicity studies of insecticide formulations to Tuta absoluta (meyrick, 1917) Ciência e Agrotecnologia
Galdino,Tarcísio Visintin da Silva; Picanço,Marcelo Coutinho; Morais,Elisangela Gomes Fidelis de; Silva,Nilson Rodrigues; Silva,Geverson Aelton Rezende da; Lopes,Mayara Cristina.
Chemical control is the main method for controlling the tomato leafminer, Tuta absoluta (Meyrick, 1917) (Lepidoptera: Gelechiidae). Reported techniques for the evaluation of insecticide toxicity to the tomato leafminer are not in agreement with field conditions and do not allow us to verify whether doses used in the field are efficient for control. Thus, the objective of this work was to develop a bioassay methodology to study the toxicity of insecticide formulations to T. absoluta that represent field conditions for fast-acting insecticides (neurotoxics and inhibitors of respiration) and slow-acting insecticides (Bacillus thuringiensis and insect growth regulators). The leaf-dip method was the most efficient method for toxicity studies of insecticides...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Susceptibility; Tomato leafminer; Chemical control; Bioassay standardization; Resistance survey.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-70542011000500002
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Comparative evaluation of the susceptibility of cultivated fishes to the natural infection with myxosporean parasites and tissue changes in the host BJB
MARTINS,M. L.; SOUZA,V. N. de; MORAES,J. R. E. de; MORAES,F. R. de; COSTA,A. J. da.
The purpose of the study was to evaluate the susceptibility of 4 important cultivated fishes to sporozoan parasites. Fishes were collected bimonthly from a pond for a period of 1 year. Myxobolus colossomatis and Henneguya piaractus were found in the internal organs and gills, respectively. The combined incidence of parasitism by both myxozoa was 97.3% in pacu (Piaractus mesopotamicus), 33.3% in hybrid tambacu (Piaractus mesopotamicus x Colossoma macropomum), 5.6% in tambaqui (Colossoma macropomum) and 0% in carp (Cyprinus carpio). Pacu was the most susceptible fish and was parasitized 79.2% in the gills, 66.7% in the kidney and 50% in the spleen. Histopathological evaluation of the gills showed hemorrhages, inflammatory reaction with mononuclear cells and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Myxozoa; Susceptibility; Histopathology; Cultivated fish.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-71081999000200010
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DETECTION OF GLYPHOSATE-RESISTANT PALMER AMARANTH (Amaranthus palmeri) IN AGRICULTURAL AREAS OF MATO GROSSO, BRAZIL Planta Daninha
CARVALHO,S. J. P.; GONÇALVES NETTO,A.; NICOLAI,M.; CAVENAGHI,A. L.; LÓPEZ-OVEJERO,R. F.; CHRISTOFFOLETI,P. J..
ABSTRACT The recent introduction of Palmer amaranth (Amaranthus palmeri) in Brazilian agricultural areas may promote several changes on weed management, especially in no-till systems and in glyphosate-resistant crops, since glyphosate-resistant biotypes of A. palmerihave been frequently selected in other countries. Therefore, this research was developed in order to evaluate the glyphosate susceptibility of a Palmer amaranth biotype recently identified in the State of Mato Grosso, Brazil. For this purpose, glyphosate susceptibility of three Amaranthusbiotypes was compared: A.hybridus var. patulus, collected in the State of Rio Grande do Sul - Brazil; A.hybridus var. patulus, collected in the State of São Paulo - Brazil; and A.palmeri, collected in the State...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pigweeds; Susceptibility; Dose-response; Management; Control.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582015000300579
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Different culture media applied to the study of Cryptococcus neoformans susceptibility to amphotericin B and fluconazole BJM
Alves,Sydney Hartz; Oliveira,Loiva T.; Goulart,Letícia S.; Linares,Carlos Eduardo B.; Griebeler,Josiane; Santurio,Janio M..
This study compared the performance of three culture media used for the determination of minimal inhibitory concentration (MIC) of amphotericin B and fluconazole against 48 Cryptococcus neoformans strains. For amphotericin B the media employed were RPMI 1640 medium, as indicated by NCCLS as reference, Yeast Nitrogen Base (YNB) as proposed by Ghannoum et al. (YNB-1), Antibiotic medium 3 (AM3) indicated by others, and YNB as proposed by us (YNB-2). In YNB-1, amphotericin B showed broader MIC ranges, varying from 0.125 µg/ml to 1.0 µg/ml; in RPMI 1640 medium and YNB-2 the MICs were similar and in AM3 the MIC ranges were narrower. The same pattern was observed for MIC 90%. For fluconazole the media employed were RPMI 1640 and YNB-1. The MIC ranges were broader...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptococcus neoformans; Susceptibility; Antifungal agents.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822002000100005
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Dual transcriptomics of virus-host interactions: comparing two Pacific oyster families presenting contrasted susceptibility to ostreid herpesvirus 1 ArchiMer
Segarra, Amelie; Mauduit, Florian; Faury, Nicole; Trancart, Suzanne; Degremont, Lionel; Tourbiez, Delphine; Haffner, Philippe; Barbosa-solomieu, Valerie; Pepin, Jean-francois; Travers, Marie-agnes; Renault, Tristan.
Background: Massive mortality outbreaks affecting Pacific oyster (Crassostrea gigas) spat in various countries have been associated with the detection of a herpesvirus called ostreid herpesvirus type 1 (OsHV-1). However, few studies have been performed to understand and follow viral gene expression, as it has been done in vertebrate herpesviruses. In this work, experimental infection trials of C. gigas spat with OsHV-1 were conducted in order to test the susceptibility of several bi-parental oyster families to this virus and to analyze host-pathogen interactions using in vivo transcriptomic approaches. Results: The divergent response of these oyster families in terms of mortality confirmed that susceptibility to OsHV-1 infection has a significant...
Tipo: Text Palavras-chave: Interactions; Ostreid herpesvirus 1; Gene expression; Susceptibility; Crassostrea gigas.
Ano: 2014 URL: http://archimer.ifremer.fr/doc/00199/31029/29431.pdf
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Etude des interactions hôte/virus chez l’huître creuse Crassostrea gigas et son virus Ostreid herpesvirus 1 ArchiMer
Segarra, Amelie.
Ostreid herpesvirus type 1 (OsHV-1) can be considered one of the major infectious agents in Pacific oysters, Crassostrea gigas, in France and all around the world. Differences in terms of mortality among infected animals were reported suggesting a genetic basis of the susceptibility to the OsHV-1 infection. In this context, the main objective of this thesis was to understand the interactions between Pacific oysters and OsHV-1, in particular, the molecular basis of the viral cycle. Results showed that the virus is able to replicate in the host regardless of its stage of development or its susceptibility. However, multiplication kinetics is faster in the most susceptible individuals compared to less susceptible ones. After an active replication phase, it...
Tipo: Text Palavras-chave: Bivalves; Huître creuse; Crassostrea gigas; Mortalités; OsHV-1; Gènes viruax; Interaction hôte-virus; Transcriptome; Sensibilité; PCR en temps réel; Bivalve; Pacific oyster; Crassostrea ggias; Mortality; OsHV-1; Viral gene; Interaction host-virus; Transcriptome; Susceptibility; Real-time PCR.
Ano: 2014 URL: http://archimer.ifremer.fr/doc/00252/36297/34826.pdf
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Genetic diversity and antifungal susceptibility testing of Trichosporon asahii isolated of Intensive Care Units patients BJM
Silva,Rosana Bellan de Oliveira; Fusco-Almeida,Ana Marisa; Matsumoto,Marcelo Teruyuki; Baeza,Lilian Cristiane; Benaducci,Tatiane; Mendes-Giannini,Maria José Soares.
Trichosporon asahii is an opportunistic pathogen, associated with a high mortality rate in immunocompromised patients. In this study, ten isolates, recovered from oral cavity and urine of patients in Intensive Care Units (ICU) over six months, were identified by classical and molecular methods, typed by RAPD and tested in vitro for susceptibility to fluconazole, itraconazole, 5-flucytosine and amphotericin B. A total agreement between the identification of Trichosporon sp by PCR based on sequences of the Internal Transcribed Spacer Regions (ITS) and on the sequences of small-subunit (SSU) ribosomal DNA (rDNA) was found. Randomly amplified of polymorphic DNA (RAPD), with primers P6 and M13, was used to determine the genomic profiles. The dendogram analysis...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Trichosporon; PCR; RAPD; Susceptibility; Antifungal drugs.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000300033
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Genetic polymorphisms and asthma: findings from a case - control study in the Madeira island population Biol. Res.
Berenguer,Anabela Gonçalves; Fernandes,Ana Teresa; Oliveira,Susana; Rodrigues,Mariana; Ornelas,Pedro; Romeira,Diogo; Serrão,Tânia; Rosa,Alexandra; Câmara,Rita.
BACKGROUND: Asthma is a complex disease influenced by multiple genetic and environmental factors. While Madeira has the highest prevalence of asthma in Portugal (14.6%), the effect of both genetic and environmental factors in this population has never been assessed. We categorized 98 asthma patients according to the Global Initiative for Asthma (GINA) guidelines, established their sensitization profile, and measured their forced expiratory volume in 1second (FEV1) and forced vital capacity (FVC) indexes. Selected single nucleotide polymorphisms (SNPs) were analysed as potential markers for asthma susceptibility and severity in the interleukin 4 (IL4), interleukin 13 (IL13), beta-2-adrenergic receptor (ADRB2), a disintegrin and metalloprotease 33 (ADAM33),...
Tipo: Journal article Palavras-chave: Asthma; Madeira; SNPs; Susceptibility; Severity.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100040
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Hospedabilidade de plantas medicinais a Meloidogyne Paranaensis. Repositório Alice
MENDONÇA, C. I. de; MATTOS, J. K. de A.; CARNEIRO, R. M. D. G..
bitstream/item/170406/1/105058-135450-1-PB.pdf
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Nematoide das galhas; Suscetibilidade; Resistance; Susceptibility; Planta medicinal; Resistência; Medicinal plants; Root-knot nematodes.
Ano: 2017 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1084366
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Host suitability of weeds and forage species to root-knot nematode meloidogyne graminicola as a funcion of irrigation management Planta Daninha
Negretti,R.R.D.; Manica-Berto,R.; Agostinetto,D.; Thürmer,L.; Gomes,C.B..
The irrigated rice production can be limited by various phytopathogenic agents, including root-knot nematodes (Meloidogyne spp.). Thus, the aim of this research was to check the host suitability of plant species most often found off-season and during rice cultivation, to root-knot nematode Meloidogyne graminicola, under two irrigation managements. Two experiments were conducted in a completely randomized design. In the first experiment seven plant species that occur in an area of rice cultivation, in fallow, off-season were evaluated. For the second experiment nine weed species infesting the irrigated rice culture were tested in rainfed and flooding conditions. The sixteen species, kept individually in pots with sterilized substrate, were inoculated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hosts; Reproduction; Susceptibility; Oryza sativa.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-83582014000300011
Registros recuperados: 58
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