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Cassien, Mathieu; Mercier, Anne; Thétiot-laurent, Sophie; Culcasi, Marcel; Ricquebourg, Emilie; Asteian, Alice; Herbette, Gaëtan; Bianchini, Jean-pierre; Raharivelomanana, Phila; Pietri, Sylvia. |
Tamanu oil from Calophyllum inophyllum L. has long been used in traditional medicine. Ethanol extraction was found the best strategy for recovering bioactive compounds from the resin part of Tamanu oil, yielding two neutral and acidic resins fractions with high phenolics, flavonoids and pyranocoumarins concentrations. A further cascade of LPLC/HPLC separations of neutral and acidic resin fractions allowed identifying fifteen metabolites, and among them, calanolide D and 12-oxocalanolide A (both in neutral fraction) were first identified from a natural source. All these extracts, subfractions and isolated metabolites demonstrated increased free radical scavenging, antioxidant, anti-inflammatory, antimicrobial and antimycobacterial activity compared to... |
Tipo: Text |
Palavras-chave: Calophyllum inophyllum L; Tamanu oil; Ethanol-soluble resin extracts; Lipophilic antioxidants; Phenolics; Pyranocoumarins; Antimicrobial; Anti-inflammatory; UV protection; EPR spin trapping. |
Ano: 2021 |
URL: https://archimer.ifremer.fr/doc/00677/78918/81283.pdf |
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Raharivelomanana, Phila; Ansel, Jean-luc; Lupo, Elise; Mijouin, Lily; Guillot, Samuel; Butaud, Jean-francois; Ho, Raimana; Lecellier, Gael; Pichon, Chantal. |
Calophyllum inophyllum L. (Calophyllaceae), locally called "tamanu" in French Polynesia, is an evergreen pantropical tree growing mostly along the seashores. Its barks, leaves, and fruits are still used in traditional medicine. The oil expressed from the nuts has been also traditionally used. Tamanu oil is topically applied on skins as well as mucous membrane lesions. This oil is especially recommended to heal all kinds of skin ailments. Bioassays and different assessments of Tamanu oil revealed numerous biological activities (antioxidant, anti-inflammatory, antibacterial, wound healing...), so bringing scientific evidence of beneficial effects of this oil on human skin healing. Such biological properties may explain the use of tamanu oil as an active... |
Tipo: Text |
Palavras-chave: Huile de tamanu; Calophyllum inophyllum; Cosmétopée; Néoflavonoïdes; Ingrédient cosmétique; Tamanu oil; Calophyllum inophyllum; Cosmetopoeia; Neoflavonoids; Cosmeceutical. |
Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00660/77218/78679.pdf |
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