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	Provedor de dados 52 (1) 77 (1) Autor Ajayi,S. A (1) Apaydin,Fatma Gokce (1) Azu,O. O (1) Bas,Hatice (1) Chuturgoon,A (1) Demir,Filiz (1) Kalender,Suna (1) Kalender,Yusuf (1) Komolafe,O. A (1) Ofusori,D. A (1) Phulukdaree,A (1) Mais... Palavra-chave Testicular toxicity (2) Antioxidant enzymes (1) Histopathology (1) Kolaviron (1) Lead nitrate (1) Nevirapine (1) Oxidative stress (1) Sodium selenite (1) Sperm count (1) Streptozotocin (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2016 (1) 2015 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Comparison of Antioxidant Effects of Kolaviron and Vitamin C Interventions on Testicular Structures Following Nevirapine Administration in Sprague-Dawley Rats 77 Ajayi,S. A; Azu,O. O; Chuturgoon,A; Phulukdaree,A; Komolafe,O. A; Ofusori,D. A. Testicular toxicity has been implicated in highly active anti-retroviral therapy (HAART) treatment. Hence there is need to identify an effective antioxidant product that can alleviate testicular necrosis due to HAART administration. Forty eight adult male Sprague-Dawley rats were used in this study. The animals were divided into eight (8) groups: A-H (n= 6). Group A animals received normal saline as the control; Group B was given Nevirapine (Nv); Group C was given Kolaviron (Kv); Group D was given vitamin C; Group E was given Nv and Kv; Group F was given Nv and Vitamin C; Group G was given Nv for 56 d and Kv for 28 d serving as a withdrawal group; Group H was given corn oil. Nv, Kv and Vit. C were given at 1.54, 200 and 250 (mg·kg)/bw respectively while... Tipo: Journal article Palavras-chave: Nevirapine; Kolaviron; Testicular toxicity; Sperm count; Antioxidant enzymes. Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100016 Lead Nitrate Induced Testicular Toxicity in Diabetic and Non-Diabetic Rats: Protective Role of Sodium Selenite 52 Apaydin,Fatma Gokce; Kalender,Suna; Bas,Hatice; Demir,Filiz; Kalender,Yusuf. Among heavy met als, lead is one of the common pollutants found in the environment and biological system. In the present study, streptozotocin-induced diabetic and normal non-diabetic male Wistar rats were given sodium selenite (1.0 mg/kg bw), lead nitrate (22.5 mg/kg bw) and sodium selenite plus lead nitrate (1.0 mg/kg+22.5 mg/kg bw, respectively) through gavage. At the end of 4th week, malondialdehyde (MDA) levels, antioxidant enzyme activities [superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST)], and histopathological changes of testes were investigated compared to the control group. No significant differences were observed between the control and sodium selenite treated groups. However, lead... Tipo: Info:eu-repo/semantics/article Palavras-chave: Testicular toxicity; Lead nitrate; Sodium selenite; Streptozotocin; Oxidative stress; Histopathology. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000100068 Registros recuperados: 2 Primeira ... 1 ... Última

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