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Registros recuperados: 53
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A bradykinin-potentiating peptide (BPP-10c) from Bothrops jararaca induces changes in seminiferous tubules J. Venom. Anim. Toxins incl. Trop. Dis.
Gilio,Joyce M; Portaro,Fernanda CV; Borella,Maria I; Lameu,Claudiana; Camargo,Antonio CM; Alberto-Silva,Carlos.
Background The testis-specific isoform of angiotensin-converting enzyme (tACE) is exclusively expressed in germ cells during spermatogenesis. Although the exact role of tACE in male fertility is unknown, it clearly plays a critical function in spermatogenesis. The dipeptidase domain of tACE is identical to the C-terminal catalytic domain of somatic ACE (sACE). Bradykinin potentiating peptides (BPPs) from snake venoms are the first natural sACE inhibitors described and their structure-activity relationship studies were the basis for the development of antihypertensive drugs such as captopril. In recent years, it has been showed that a number of BPPs - including BPP-10c - are able to distinguish between the N- and C-active sites of sACE, what is not...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bradykinin-potentiating peptide; Snake venom; Angiotensin-converting enzyme; Testis; Seminiferous epithelium.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992013000100316
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A Study of the Staining Effect of Roselle (Hibiscus sabdariffa) on the Histologic Section of the Testis International Journal of Morphology
Egbujo,E. C.; Adisa,O. J; Yahaya,A. B.
This study describes the preparation and use of Roselle (Hibiscus sábddariffa) for the differential staining of testicular tissue sections to find out its staining effect on nuclear, cytoplasmic and other structures. Various treatments using modifications of the plant extract in water were carried out on sections of the rabbit testis. Various levéis of differentiation of nuclear and cytoplasmic structures as well as other structures of this organ was obtained especially when 1% eosin was applied as a counter stain. The best staining result was obtained when iron alum was used to mordant the extract and when the extract, mordanted with potassium alum was acidified using acetic acid and used to stain the sections. Modification of the aqueous extract to an...
Tipo: Journal article Palavras-chave: Hibiscus sabdariffa; Staining; Testis; Histologic section.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400022
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A transcriptome analysis of mitten crab testes (Eriocheir sinensis) Genet. Mol. Biol.
Zhang,Wei; Wan,Haolei; Jiang,Hui; Zhao,Yunlong; Zhang,Xiaowei; Hu,Songnian; Wang,Qun.
The identification of expressed genes involved in sexual precocity of the mitten crab (Eriocheir sinensis) is critical for a better understanding of its reproductive development. To this end, we constructed a cDNA library from the rapid developmental stage of testis of E. sinensis and sequenced 3,388 randomly picked clones. After processing, 2,990 high-quality expressed sequence tags (ESTs) were clustered into 2,415 unigenes including 307 contigs and 2,108 singlets, which were then compared to the NCBI non-redundant (nr) protein and nucleotide (nt) database for annotation with Blastx and Blastn, respectively. After further analysis, 922 unigenes were obtained with concrete annotations and 30 unigenes were found to have functions possibly related to the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Reproduction; Testis; EST; Eriocheir sinensis.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100024
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Anatomical Study on Domestical Fowl (Gallus domesticus) Reproductive System International Journal of Morphology
Bull,Marilena Longo; Martins,Márcia Regina Fernandas Boaro; Dalva Cesário,Maria; Padovani,Carlos Roberto; Mendes,Ariel Antonio.
Lately, researchers have taken into consideration studies on birds since they represent an excellent nutritional source. There are several classical descriptions of the male reproductive tract, always aiming at establishing a correlation with shape, testicular size, age and sexual maturity. This study analyzed 50 male Gallus domesticus, 1 to 64 weeks old. The birds were collected with 10 days and then weekly until 24 weeks, following 37, 48, 59 and 64 weeks, and sacrificed by cervical displacement. It was observed the sintopies of testis with the other organs. Further, it was done the testicular measurement and then the statistical analysis by following the model of testis weight variation due to the animal age. Our results showed that the maximum weight...
Tipo: Journal article Palavras-chave: Anatomy; Testis; Fowl.
Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400007
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Anatomical Study on the Descent of Testis in Prenatal Goat (Capra hircus) International Journal of Morphology
Farooqui,M. M; Archana,Chandrapal; Prakash,Ajay.
A study was conducted on 70 embryo/ foetii of goats to observe the descent of testis. These foetii were grouped into I (0-30 days), II (31-60 days), III (61-90 days), IV (91-120days) and V (121 days up to term, having 14 embryos/ foetii in each group. The genital ridge was observed at 1.2cm CRL (23 day) on the ventromedial aspect of mesonephros. At 42nd day, the genital ridge developed into cylindrical structure, the testis, located in the middle of metanephros. The abdominal migration was completed upto 88th day. The testes were situated in the inguinal canal from 89th to 95th day. From 90th day onward, scrotal migration had been observed, however the testis did not reach the base of the scrotum up to term. During the descent of testis, a peritoneal fold...
Tipo: Journal article Palavras-chave: Anatomy; Testis; Gubernaculum; Goat.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000200002
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Anti-Müllerian hormone as an indicator of hemi-castrated unilateral cryptorchid horses OAK
MURASE, Harutaka; SAITO, Shigeaki; AMAYA, Tomohiko; SATO, Fumio; BALL, Barry Allen; NAMBO, Yasuo.
Anti-Müllerian hormone (AMH), a glycoprotein secreted from the fetal testis, is responsible for regression of the Müllerian duct in the male fetus. The aim of this study was to evaluate the usefulness of serum AMH as a biomarker for diagnosis of cryptorchidism in horses. Serum AMH concentrations were measured in intact stallions, hemi-castrated unilateral cryptorchid stallions, and geldings. In addition, expression of AMH was characterized in cryptorchid testes by immunohistochemistry. Serum AMH was detected in intact stallions (n=11, 13.3 ± 1.8 ng/ml) and in hemi-castrated cryptorchid stallions (n=8, 17.6 ± 3.0 ng/ml), but not in geldings (n=6, all data were below the limit of detection). Immunolabeling for AMH was detected in Sertoli cells of undescended...
Palavras-chave: Anti-Müllerian hormone (AMH); Cryptorchidism; Equine; Testis.
Ano: 2015 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4151
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Antioxidant Status, Lipid Peroxidation and Testis-histoarchitecture Induced by Lead Nitrate and Mercury Chloride in Male Rats BABT
Bas,Hatice; Kalender,Suna.
ABSTRACT This study was done to evaluate the effects of lead nitrate and mercury chloride in testis tissues of Wistar rats. Lead nitrate and mercury chloride are widely used heavy metals in industry. Oral lead and mercury administrations to adult male rats at doses 45 mg/kg bw and 0.02 mg/kg bw, respectively for 4 weeks caused a significant increasing in MDA levels and antioxidant enzyme activities (SOD, CAT, GPx and GST). The MDA levels and acivities of antioxidant enzymes was lower in rats that were administrated by lead nitrate than mercury chloride treated group. Light microscopic analyses revealed that lead nitrate and mercury chloride induced numerous histopathological changes in testis tissues of rats. Histopathological observations of the testis...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant enzymes; Lead; Mercury; Oxidative stress; Testis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100341
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Cat, cougar, and jaguar spermatogenesis: a comparative analysis BABT
Costa,Deiler Sampaio; Paula,Tarcízio Antônio Rêgo; Matta,Sérgio Luiz Pinto da.
This work presents a comparative review about the spermatogenic process in cats (Felis domestica), jaguars (Panthera onca) and cougars (Puma concolor), with emphasis on testicular biometry, gonadossomatic index, volumetric proportion of testicular parenchyma components, tubular diameter, seminiferous epithelial height and seminiferous tubule length. It was an approach of the differences among the cell proportions that allowed conclusions about the overall yield of spermatogenic process and Sertoli cell index in three feline species.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Spermatogenesis; Felines; Testis.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000600006
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Contribution of environmental pollutants to male infertily: A working model of germ cell apoptosis induced by plasticizers Biol. Res.
Lagos-Cabré,Raúl; Moreno,Ricardo D.
Bisphenol A [2,2-bis(4-hydroxyphenyl)propane] (BPA), 4-nonylphenol (NP) and di(2-ethylhexyl)phthalate (DEHP), and its metabolite mono-2-ethylhexyl phthalate (MEHP) are chemicals found in plastics, which act as endocrine disruptors (EDs) in animals, including human. EDs act like hormones in the endocrine system, and disrupt the physiologic function of endogenous hormones. Most people are exposed to different endocrine disruptors and concern has been raised about their true effect on reproductive organs. In the testis, they seem to preferentially attack developing testis during puberty rather than adult organs. However, the lack of information about the molecular mechanism, and the apparently controversial effect observed in different models has hampered the...
Tipo: Journal article Palavras-chave: Testis; Spermatogenesis; Bisphenol A; Nonylphenol; ADAM17.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000100001
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Differential expression and localization of ADAM10 and ADAM17 during rat spermatogenesis suggest a role in germ cell differentiation Biol. Res.
Urriola-Muñoz,Paulina; Lizama,Carlos; Lagos-Cabré,Raúl; Reyes,Juan G; Moreno,Ricardo D.
BACKGROUND: Extracellular metolloproteases have been implied in different process such as cell death, differentiation and migration. Membrane-bound metalloproteases of the ADAM family shed the extracellular domain of many cytokines and receptor controlling auto and para/juxtacrine cell signaling in different tissues. ADAM17 and ADAM10 are two members of this family surface metalloproteases involved in germ cell apoptosis during the first wave of spermatogenesis in the rat, but they have other signaling functions in somatic tissues. RESULTS: In an attempt to further study these two enzymes, we describe the presence and localization in adult male rats. Results showed that both enzymes are detected in germ and Sertoli cells during all the stages of...
Tipo: Journal article Palavras-chave: Testis; Spermatogenesis; Apoptosis; Paracrine; Metalloproteinase.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100031
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Effect of Diet Contains Sesame Seed on Adult Wistar Rat Testis International Journal of Morphology
Amini Mahabadi,J; Hassani Bafrani,H; Nikzad,H; Taherian,A; Salehi,M.
Studies show that some antioxidants are effective in improving male infertility. According to several antioxidant compounds that exist in sesame seed, this study was designed and carried out to the effects of sesame seed diet consumption on adult male rats testis structure and sex hormones. This experimental study was carried out on 30 adults Wistar rat, 200 g that obtained from laboratory animal center at Kashan University of Medical Sciences. Rats were divided into experimental and control groups randomly. The control group received standard diet and experimental group received diet containing 70% standard diet and 30% sesame seed after weaning for 12 weeks. At the end of the study, testis weight and volume were measured and seminiferous tubules; lumen...
Tipo: Journal article Palavras-chave: Sesame seed; Testis; Rat; Sex hormones.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100033
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Effect of Photoperiod and Melatonin on Volume and Cellular Parameters of Testis in Pinealectomized Rats International Journal of Morphology
Akosman,Murat Sirri; Özdemir,Vural; Taskiran,Nihal; Akalan,Mehmet Aydin; Bülbül,Aziz.
Mammalian reproductive axis is regulated by the combination of three fundamental tissues of neuroendocrine system including hypothalamus, hypophysis and gonads. In recent years, pineal gland has been included in this axis. The aim of the present study was to investigate the effect of 12L (Light):12D (Dark) photoperiod and melatonin administration (0.5 mg/kg/day; subcutaneously) on testicular volume and cellular parameters of testis at the pinealectomized (PE) rats. For this aim, twelve adult rats were firstly pinealectomized and then divided into two groups as GI and GII randomly. The GI rats served as control group and received only normal saline, whereas GII rats were the melatonin administered group. It was found that the total testicular volume,...
Tipo: Journal article Palavras-chave: Cavalieri Method; Melatonin; Optical Fractionator; Pinealectomy; Stereology; Testis.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000300046
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Effects of catuaba cristal® on the testis of wistar rats BABT
Freitas,Karine Moura de; Costa,Kyvia Lugate; Campos,Pamela Kelly Araújo; Melo,Fabiana Cristina Silveira Alves de; Paula,Tarcízio Antônio Rego de; Matta,Sérgio Luis Pinto da.
The aim of this study was to evaluate the possible beneficial effects of Catuaba Cristal® (CC), an alcoholic drink made from wine and Erythroxylum catuaba Ar. Cam on testis. Wistar rats either received CC solution (n=8) or water (n=9). Results showed significant body weight reduction within the CC group, although, no weight changes were observed for liver, kidney, testis, epididymis, seminal vesicle and prostate. The volumetric proportion and volume of interstitial tissue and lymphatic space were reduced in the treated group. In the CC group, although the nuclear volume of Leydig cells (LC) decreased, the number of LC per testis increased. These results suggested that CC had no beneficial effect on spermatogenesis of Wistar rats.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aphrodisiac drink; Medicinal plants; Morphometry; Spermatogenesis; Testis.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000500007
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Effects of Chronic Simulated Hypobaric Hypoxia on Mouse Spermatogenesis International Journal of Morphology
Bustos-Obregón,Eduardo; Esveile,Christian; Contreras,Julio; Maurer,Inge; Sarabia,Luis.
Reduction of O2 delivery to tissues damage them, including the seminiferous epithelium. Recently, population working in high altitude has increased, so that the study of hypobaric hypoxia on spermatogenesis becomes of interest. In this study we used two groups of male, sexually mature mice Control (C) (540 meters above sea level (masl)) and chronic simulated hypobaric hypoxia (CSHH) (4,600 masl) exposed during 8, 16, 24 or 33 days. Hematocrit; reticulocytosis; testicular, epididymal and seminal vesicle weight; seminiferous epithelium height, tubular diameter, sperm count and morphology and testicular parenchyme and spermatozoa membranes lipoperoxidation were measured. Weight of testis, epididymis and seminal vesicle were reduced but they recuperate at 33...
Tipo: Journal article Palavras-chave: Hypoxia; Lipoperoxidation; Mouse; Testis.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400030
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Effects of low-protein diets supplemented with antioxidants on histopathology of testis and testosterone and performance of male Japanese quail ( Coturnix coturnix japonica ) R. Bras. Zootec.
Mahmoodpour,Hamid; Vahdatpour,Sina; Jafargholipour,Mohamadali; Vahdatpour,Tohid.
ABSTRACT The present study sought to examine the effects of low-protein diets supplemented with natural and synthetic antioxidants on reproductive traits and performance of male Japanese quail. A total of 144 one-day-old quail chicks were randomly assigned to receive four different treatments, including a control diet (a basal diet) without antioxidant supplementation, low-protein diet without antioxidant supplementation, low-protein diet supplemented with the E-selenium antioxidant (a combination of vitamin E and selenium), and low-protein diet supplemented with the antioxidant Loxidan (a combination of propyl galat, ethoxyquin, and citric acid). Throughout the study, feed and water were provided ad libitum from one to 45 days of age. Performance values...
Tipo: Info:eu-repo/semantics/article Palavras-chave: E-selenium; Loxidan; Performance; Protein; Quail; Testis; Testosterone.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982017000200123
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Expression of caveolin-1 in rat Leydig cells Biocell
Casanova,Marta B..
Caveolin-1, the first member of caveolin family reported, is recognized as the structural component of caveola, a plasma membrane invagination or vesicles that are a subcompartment distinct from clathrin-coated pits. This protein is also known to be involved in cholesterol trafficking. The aim of this study was to determine the expression of caveolin-1 in adult rat Leydig cells. Testis sections incubated with an antibody to caveolin-1 showed, by immunohistochemistry, a moderate number of Leydig cells with different degrees of immunoreaction and a strong reaction in endothelial cells and in the lamina propia of seminiferous tubules. Caveolin-1 was detected in the cell cytoplasm with a granular pattern and on the cell surface of Leydig cells cultured 24 h on...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Testis; Leydig cells; Caveolin-1.
Ano: 2006 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000300003
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Histological and Histochemical Studies on the Prenatal Development of Testis in Goat (Capra hircus) International Journal of Morphology
Farooqui,M. M; Archana,Chandrapal; Prakash,Ajay.
The study has been conducted on the prenatal development of testis on 70 goat embryo/foeti, categorized into group-I (0-30 days), Group-II (31-60 days), Group-III (61-90 days), Group-IV (91-120 days) and group V (121days-till birth), having 14 embryos/ foeti in each group. The genital ridge was observed at 23 days of gestation. It contained an accumulation of mesenchymal cells, immature RBC's, differentiating fibroblasts and primordial germ cells. The formation of sex cords was evidenced on 44th day of gestation. It contained small mesenchymal cells and large cells arranged in a chain like manner. The convolution of the sex cords started between 61-90 days of gestation, which increased with the increase in the gestation period and at 125 day of gestation...
Tipo: Journal article Palavras-chave: Testis; Prenatal development; Goat.
Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000400024
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Histological and Morphometric Analysis of Testes of Adult Quail (Coturnix coturnix japonica) of Bangladesh International Journal of Morphology
Shil,Subrata Kumar; Quasem,Md. Abul; Rahman,Mohammad Lutfur.
A histological and morphometric study was conducted to evaluate the seasonal testicular variations in the adult Japanese quail (Coturnix coturnix japonica) in Bangladesh. The weight of birds and testes, volume, length, circumference, seminiferous tubule diameter, circumference and height of germinal epithelium of testes were measured. Sections of testes obtained from studied birds were stained with H&E and images were taken by J software. Weight and volume of paired testes of quails significantly heavier (P<0.05) in long day period of summer and rainy season (March ­ September) than the short day period of autumn and winter (October ­ February). Seasons had no significant effect on live weight gain of quails. The weight and diameter of testes or...
Tipo: Journal article Palavras-chave: Japanese quail; Morphometry; Testis; Season; Day length; Temperature.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000100017
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HISTOLOGICAL DESCRIPTION OF THE REPRODUCTIVE SYSTEM OF MALE AND FEMALE HATCHLINGS OF THE MAGDALENA RIVER TURTLE (Podocnemis lewyana) Acta biol.Colomb.
SÁNCHEZ-OSPINA,ANDRÉS C; RODRIGUEZ,BERARDO; CEBALLOS,CLAUDIA P..
In this study we described the macroscopic and microscopic histology of the reproductive system of male and female Podocnemis lewyana neonates (3.5 months old). We found macroscopic differences in the morphology of the gonads between the sexes, with ovaries being twice as long as testes, and testes being twice as wide as ovaries. Microscopically, we identified several immature elements, such as the lack of a muscle layer in the oviduct of females, and simple epithelia instead of pseudostratified epithelia in the oviduct and epididymis described in reptile adults. We also found a black pigment observed macroscopically in the mesovarium, and macroscopically and histologically in the epididymis. This pigment is consistent with the center of melano-macrophages...
Tipo: Journal article Palavras-chave: Epididymis; Histology; Ovary; Oviduct; Pigment; Testis.
Ano: 2014 URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-548X2014000300009
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Histopathological changes in albino mouse testis induced by the administration of Tityus n. sp. venom J. Venom. Anim. Toxins
PENNA-VIDEAÚ,S.; CERMEÑO-VIVAS,J.; MORENO-MARVAL,M.; QUIROGA-NOTTI,M..
Scorpion envenoming is a public health concern in northeastern Venezuela. Specimens of the genus Tityus are responsible for most of these. In experimental animals, Tityus venom produces histopathological changes in the skeletal muscle and pancreas, but its toxicity to the reproductive system has not been studied. The aim of this work is to describe the histopathological changes in testis and epididymis of albino mice induced by the administration of Tityus n. sp. venom. Sub-lethal doses of venom (3.75 mg/g mouse) were administered intramuscularly (IM) daily for 4 days. On the fifth day, the animals were sacrificed and the testes and epididymes were quickly removed and processed for light microscopy. The venom induced alterations in spermatogenesis. Sertoli...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Testis; Sertoli cell; Epididymis; Scorpion; Venom; Mouse; Histopathology.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200003
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