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Ameliorative Effects of Thymoquinone on Sperm Parameters and Testosterone Level of Nicotine-Treated Sprague Dawley Rats BABT
Rosli,Farah Dayana; Hashim,Noor Hashida; Osman,Khairul; Ibrahim,Siti Fatimah; Kabir,Nurul.
Abstract Thymoquinone (TQ), the main constituent of the volatile oil derived from Nigella sativa has shown pharmacological benefits against various diseases while nicotine is an active component in cigarette that is known to be detrimental. This study was conducted to assess the ameliorating effects of TQ on sperm count, membrane, mitochondria and testosterone of nicotine-treated rats. Rats were randomized into four groups: control, nicotine, TQ, and nicotine with TQ. Nicotine (5 mg/kg bwt/day) was subcutaneously injected for 30 days to induce damaging effects on sperm and testosterone level. Rats were force-fed with TQ (5 mg/kg bwt/day) for the following 30 days. Sperm count was reduced in the nicotine group (26.72 ± 1.64 106/mL) but showed a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Thymoquinone; Nicotine; Rat sperm; Membrane; Mitochondria; Testosterone.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100304
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Association of the infusion of Heteropterys aphrodisiaca and endurance training brings spermatogenetic advantages Biol. Res.
Gomes,Marcos L M; Monteiro,Juliana C; Freitas,Karine M; Sbervelheri,Mariana M; Dolder,Heidi.
The species Heteropterys aphrodisiaca is commonly used as a stimulant by popular medicine in the Cerrado, a savanna-like biome, Brazil. Recent studies have proved its protective effects on testes of animals submitted to treatment using Cyclosporine A, as well as its stimulus effect in increasing testosterone secretion. Therefore, the present study was designed to analyze whether the association of the plant infusion and endurance exercise could potentiate the stimulating effect. The animals were separated into 4 groups: two control (sedentary and trained) receiving water and two treated (sedentary and trained) receiving the plant infusion daily (104mg/day). The proportion of the seminiferous tubule compartment and interstitium was analyzed. Within the...
Tipo: Journal article Palavras-chave: Germ cells; Phytotherapy; Seminiferous epithelium; Spermatogenesis; Testosterone.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000300004
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Behavioral cross-sensitization between testosterone and fenproporex in adolescent and adult rats BJMBR
Conceição,C.Q.; Engi,S.A.; Cruz,F.C.; Planeta,C.S..
The abuse of psychoactive drugs is considered a global health problem. During the last years, a relevant number of studies have investigated the relationship between anabolic-androgenic steroids (AAS) and other psychoactive drugs. AAS, such as testosterone, can cause a dependence syndrome that shares many features with the classical dependence to psychoactive substances. Pre-clinical evidence shows that there are interactions between testosterone and psychoactive drugs, such as cocaine. However, few studies have been performed to investigate the effect of repeated testosterone treatment on behavioral effects of amphetamine derivatives, such as fenproporex. The purpose of the present study was to investigate the effects of repeated testosterone...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Behavioral sensitization; Fenproporex; Testosterone; Rats.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000100603
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Changes in the hormone and lipid profile of obese adolescent Saudi females with acne vulgaris BJMBR
Abulnaja,K.O..
Acne vulgaris is a multifactorial disease affecting a majority of the adolescent population. The objective of this study was to test for a correlation between fasting serum lipid profiles and levels of testosterone, insulin, leptin, and interleukin 1-β (IL-1β) and the incidence of severe acne vulgaris in obese adolescent females. Four groups of adolescent females were studied: obese with acne, obese without acne, non-obese with acne, and non-obese without acne. Obese females with acne, compared to obese females without acne and non-obese subjects, had significantly higher serum triglycerides, low-density lipoprotein cholesterol and apolipoprotein-B (apo-B) (mean ± SD: 197 ± 13.7 vs 171 ± 11.5, 128 ± 8.3 vs 116 ± 7.7, 96 ± 13.7 vs 85 ± 10.3 mg/dL,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acne vulgaris; Obesity; Testosterone; Adolescent females; Serum IL-1β.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600005
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Comparison of serum hormone levels of captive and free-living maned wolves Chrysocyon brachyurus BJMBR
Maia,O.B.; Jácomo,A.T.A.; Bringel,B.A.; Kashivakura,C.K.; Oliveira,C.A.; Teodoro,L.O.F.; Silveira,L.; Teixeira da Costa,M.E.L.; Malta,M.C.C.; Furtado,M.M.; Torres,N.M.; Mattos,P.S.R.; Viau,.P; Lima,T.F.G.; Morato,R.G..
Serum hormone levels were compared between captive and free-living maned wolves and seasonal variations of sex hormones were studied. Blood samples were collected from 16 male and 26 female adult animals from Brazilian zoos, and from 30 male and 24 female free-living adults to determine serum progesterone and testosterone by radioimmunoassay. Serum testosterone concentrations varied (P < 0.05) across seasons for 16 captive males, being higher in autumn (2184.7 ± 355.1 pg/mL) than in summer (1080.7 ± 205.4 pg/mL), winter (1270.1 ± 276.6 pg/mL) and spring (963.9 ± 248.1 pg/mL), although they did not differ between summer, winter and spring. Testosterone concentration of 30 free-living males differed (P < 0.05) between autumn (824.1 ± 512.2 pg/mL),...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Maned wolf Chrysocyon brachyurus; Progesterone; Testosterone; Radioimmunoassay; Reproduction.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000200015
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Comportamento sexual, biometria testicular, aspectos do semen e niveis plasmaticos de testosterona em touros Canchim e Nelore. Repositório Alice
BARBOSA, R. T..
As relacoes entre os aspectos fisicos e morfologicos do semen, biometria testicular, comportamento sexual e os niveis plasmaticos de testosterona foram comparadas em 7 touros Canchim e 8 Nelore aos 28 meses de idade.
Tipo: Tese/dissertação (ALICE) Palavras-chave: Comportamento sexual; Biometria testicular; Testiculo; Aspectos do semen; Niveis plasmatico; Testosterona; Touros; Bovino; Raca Canchim; Nelore; Nellore; Beef cattle; Sexual behavior; Testosterone.
Ano: 1987 URL: http://www.alice.cnptia.embrapa.br/handle/doc/35005
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Computer simulations for biological aging and sexual reproduction Anais da ABC (AABC)
STAUFFER,DIETRICH; OLIVEIRA,PAULO M.C. DE; OLIVEIRA,SUZANA MOSS DE; PENNA,THADEU J.P.; MARTINS,JORGE S. SÁ.
The sexual version of the Penna model of biological aging, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving aging. In particular we want to check how sexual forms of life could have evolved and won over earlier asexual forms hundreds of million years ago. This computer model is based on the mutation-accumulation theory of aging, using bits-strings to represent the genome. Its population dynamics is studied by Monte Carlo methods.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Parthenogenesis; Genome; Menopause; Testosterone; Monte Carlo simulation.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100003
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Concentrações plasmaticas de testosterona e suas relações com características reprodutivas em touros das raças Canchim e Nelore. Repositório Alice
BARBOSA, R. T.; FONSECA, V. O.; BARBOSA, P. F.; ALENCAR, M. M. de.
Níveis plasmaticos de testosterona foram determinados em 7 touros da raça canchim e 8 touros da raça nelore, aos 27 e 39 meses de idade.
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Touros; Gado Canchim; Gado Nelore; Reprodução animal; Testosterona; Bulls; Nellore; Animal reproduction; Testosterone.
Ano: 1992 URL: http://www.alice.cnptia.embrapa.br/handle/doc/42254
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Correlation between sperm characteristics and testosterone in bovine seminal plasma by direct radioimmunoassay R. Bras. Zootec.
Souza,Luiz Waldemar de Oliveira; Andrade,André Furugen Cesar; Celeghini,Eneiva Carla Carvalho; Negrão,João Alberto; Arruda,Rubens Paes de.
The objectives of this study were to validate a non-extractive RIA for seminal testosterone and quantify the hormone using a solid-phase commercial kit, and study the correlation between testosterone in seminal plasma and sperm characteristics. Parallelism showed a correlation index r = 0.992 (Y = -5.47 + 1.073X; R² = 0.985), indicating that the non-extractive method presented is indicated particularly for assessment of testosterone when establishing comparisons between samples. Overall mean (±SD) of testosterone level was 0.60±0.65 ng/mL. Correlation was only found between the seminal concentrations of testosterone and pH of the semen.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bull; Hormone; RIA; Semen; Spermatozoa; Testosterone.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982011001200015
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Decreased muscle strength is associated with proinflammatory cytokines but not testosterone levels in men with diabetes BJMBR
Ferreira,J.P.; Leal,A.M.O.; Vasilceac,F.A.; Sartor,C.D.; Sacco,I.C.N.; Soares,A.S.; Salvini,T.F..
The aim of this study was to compare muscle strength in male subjects with type 2 diabetes mellitus (DM2) with and without low plasma testosterone levels and assess the relationship between muscle strength, testosterone levels, and proinflammatory cytokines. Males (75) aged between 18 and 65 years were divided into 3 groups: control group that did not have diabetes and had a normal testosterone plasma level (>250 ng/dL), DnormalTT group that had DM2 with normal testosterone levels, and the DlowTT group that had DM2 and low plasma testosterone levels (<250 ng/dL). The age (means±SD) of the groups was 48.4±10, 52.6±7, and 54.6±7 years, respectively. Isokinetic concentric and isometric torque of knee flexors and extensors were analyzed by an isokinetic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetes; Testosterone; Muscle strength; Cytokines.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000900610
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Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty BJMBR
Almeida,S.A.; Petenusci,S.O.; Anselmo-Franci,J.A.; Rosa-e-Silva,A.A.M.; Lamano-Carvalho,T.L..
We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prolactin increased 135% and 48%, respectively, while plasma luteinizing hormone and testosterone presented a significant decrease of 29% and 37%, respectively. Plasma concentration of follicle-stimulating hormone was not altered in stressed rats. Chronic stress reduced the amount of mature spermatids in the testis by 16% and the spermatozoon concentration in the cauda epididymidis by 32%. A 17% reduction in weight and a 42% decrease in DNA content were observed in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immobilization; Spermatogenesis; LH; FSH; Testosterone; Prolactin.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100013
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Desempenho produtivo de bovinos de corte submetidos a dois métodos de castração na Amazônia Ocidental. Repositório Alice
PARU, A. B..
No Acre, a castração é uma prática comum no manejo das propriedades que criam bovinos de corte. Esse procedimento geralmente é feito dos 30 aos 36 meses de idade, aproveitando o maior desenvolvimento dos bovinos não castrados. Este trabalho avaliou o desempenho produtivo dos bovinos não castrados ou submetidos à castração convencional e à imunocastração. O experimento foi realizado de março de 2016 a janeiro de 2017. O experimento foi inteiramente casualizado com 34 repetições (animais) de três tratamentos (não castrado, castrado cirurgicamente e imunocastrados). Foram determinados os níveis produtivos dos animais, os níveis de testosterona circulante, além do rendimento e acabamento de carcaça e do lucro gerado por cada método após o abate. Constatou-se...
Tipo: Tese/dissertação (ALICE) Palavras-chave: Bopriva; Castração cirúrgica; Surgical ablation; Immunocastration; Producción de carne; Imunocastração; Ganado de carne; Raza de bovinos Nelore; Castración; Inmunocastración; Calidad de canales; Rentabilidad; Ablación quirúrgica; Acre; Amazônia Ocidental; Western Amazon; Amazonia Occidental; Gado de Corte; Gado Nelore; Produção de Carne; Castração; Ganho de Peso; Testosterona; Carcaça; Lucro; Beef cattle; Nellore; Meat production; Castration; Weight gain; Testosterone; Carcass quality; Profitability.
Ano: 2018 URL: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1105747
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Different stress modalities result in distinct steroid hormone responses by male rats BJMBR
Andersen,M.L.; Bignotto,M.; Machado,R.B.; Tufik,S..
Since both paradoxical sleep deprivation (PSD) and stress alter male reproductive function, the purpose of the present study was to examine the influence of PSD and other stressors (restraint, electrical footshock, cold and forced swimming, N = 10 per group) on steroid hormones in adult Wistar male rats. Rats were submitted to chronic stress for four days. The stressors (footshock, cold and forced swimming) were applied twice a day, for periods of 1 h at 9:00 and 16:00 h. Restrained animals were maintained in plastic cylinders for 22 h/day whereas PSD was continuous. Hormone determination was measured by chemiluminescent enzyme immunoassay (testosterone), competitive immunoassay (progesterone) and by radioimmunoassay (corticosterone, estradiol, estrone)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Paradoxical sleep deprivation; Stress; Testosterone; Progesterone; Estrogen; Corticosterone.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000600003
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Effect of Intermittent Feeding on Gonadal Function in Male And Female NMRI Mice During Chronic Stress BABT
Ehteram,Badri Zarrin; Sahraei,Hedayat; Meftahi,Gholam Hossein; Khosravi,Maryam.
ABSTRACT Stress can inhibit gonadal activity via Hypothalamus-Pituitary-Gonad (HPG) axis activity suppression. In the present study, effects of intermittent feeding (IF) on gonadal function under stress in male and female mice were evaluated. Twenty eight male and twenty eight female mice's were divided into four groups. The control group received adequate food and water without stress. The second group received four days of electric shock without food deprivation. The third group was deprived of food two hours/day for a week, and the fourth group was deprived of food (2 hours/day for seven consecutive days) and then electric foot shock stress was applied to them for four days. Blood samples were collected from all animals for plasma testosterone, estrogen...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Estrogen; Gonad; IL-6; Intermittent Feeding; Stress; Testosterone.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100439
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Effect of metformin on semen quality BJPS
Banihani,Saleem Ali.
ABSTRACT Various studies have linked metformin, a universally antidiabetic drug, with semen quality; however, such a direct link has not been established. This review systematically addresses and summarizes the effect of metformin on semen quality, particularly sperm function. We searched the MEDLINE electronic database for English articles and abstracts containing the key words 'metformin' and 'sperm', and relevant articles were reviewed. In summary, metformin appears to have improved and provided positive impact on sperm quality. This effect may be due to the ability of metformin to reduce oxidative stress and lipid peroxidation, enhance 5'-AMP activated protein kinase activity, and restore the normal levels of pituitary-gonadal hormones. However,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metformin/effects; Metformin/review; Metformin/semen quality; Sperm/study; Testosterone; Oxidative stress; 5'-AMP activated protein kinase..
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400591
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Effect of sildenafil (Viagra®) on the genital reflexes of paradoxical sleep-deprived male rats BJMBR
Andersen,M.L.; Bignotto,M.; Tufik,S..
Since there is evidence that paradoxical sleep deprivation (PSD) elicits penile erection (PE) and ejaculation (EJ), and that the erectile response of rats is mediated by nitric oxide, the present study sought to extend the latter finding by assessing the effects of sildenafil on the genital reflexes of male Wistar rats subjected to PSD. We also determined the influence of sildenafil on hormone concentrations. In the first experiment, sildenafil at doses ranging from 0.08 to 0.32 mg/kg was administered intraperitoneally to rats that had been deprived of sleep for 4 days and to home cage controls (N = 8-10/group). The frequency of PE and EJ was measured for 60 min. PSD alone induced PE in 50% of the animals; however, a single injection of sildenafil did not...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Paradoxical sleep deprivation; Sildenafil; Genital reflexes; Dopamine; Testosterone; Progesterone.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100008
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Effects of low-protein diets supplemented with antioxidants on histopathology of testis and testosterone and performance of male Japanese quail ( Coturnix coturnix japonica ) R. Bras. Zootec.
Mahmoodpour,Hamid; Vahdatpour,Sina; Jafargholipour,Mohamadali; Vahdatpour,Tohid.
ABSTRACT The present study sought to examine the effects of low-protein diets supplemented with natural and synthetic antioxidants on reproductive traits and performance of male Japanese quail. A total of 144 one-day-old quail chicks were randomly assigned to receive four different treatments, including a control diet (a basal diet) without antioxidant supplementation, low-protein diet without antioxidant supplementation, low-protein diet supplemented with the E-selenium antioxidant (a combination of vitamin E and selenium), and low-protein diet supplemented with the antioxidant Loxidan (a combination of propyl galat, ethoxyquin, and citric acid). Throughout the study, feed and water were provided ad libitum from one to 45 days of age. Performance values...
Tipo: Info:eu-repo/semantics/article Palavras-chave: E-selenium; Loxidan; Performance; Protein; Quail; Testis; Testosterone.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982017000200123
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Effects of prenatal stress on male offspring sexual maturity Biocell
Rodríguez,Nancy; Mayer,Nora; Gauna,Héctor F.
Prenatal stimulations have been shown to have long-term effects on at reproductive activity. We evaluated the influence of the prenatal stress on the hypothalamic-pituitary-gonad (HPG) axis in male off­springs from mothers with high number of offsprings per litter (HNL) and low number of offsprings per litter (LNL) after hypothesizing that the number of offsprings per litter may modify the effect of the prenatal stress on the HPG of adult offsprings. Pregnant Wistar rats were used for this study. Immobilization (IMO) stress was used, 30 min, 3 times per week, from the 5th to 21st day of pregnancy. The weight of adrenal and gonads, and the corticosterone (COR), testosterone (TES) and luteinizing hormone (LH) plasmatic levels were analyzed in the male...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rats; Prenatal stress; Reproduction; Corticosterone; Testosterone.
Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452007000100008
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Impact of feeding cottonseed coproducts on reproductive system of male sheep during peripubertal period Scientia Agricola
Paim,Tiago do Prado; Viana,Pauline; Brandão,Eduardo; Amador,Samara; Barbosa,Tatiana; Cardoso,Caio; Lucci,Carolina Madeira; Souza,Jurandir Rodrigues de; McManus,Concepta; Abdalla,Adibe Luiz; Louvandini,Helder.
ABSTRACT Cottonseed coproducts contain gossypol which can have specific effects upon the male reproductive system. We evaluated the reproductive development of male lambs close to puberty fed on three cotton coproducts. Twenty-four 5-month old male lambs received four diets: 20 % of dry matter intake of whole cottonseed (WCS), high oil cottonseed meal (CSC), cottonseed meal (CSM), and a control group (CTL) without any cottonseed coproducts. Free gossypol intake was 16.32, 6.98, 5.47 and 0 mg kg−1 BW−1 d−1 for WCS, CSC, CSM and CTL, respectively. Every 15 days, the animals were weighted and serum and semen samples were collected. After 95 days, testis samples were collected for analysis under light and transmission electron microscopes. The CTL group had...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gossypol; Sperm; Testis; Testosterone; Lamb.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162016000600489
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Influência do Hormônio do Crescimento na concentração de testosterona plasmática e nas características seminais de touros jovens e adultos da raça Nelore. Repositório Alice
AMORIM, L. S.; KAWAMOTO, T. S.; TORRES, C. A. A.; GUIMARÃES, J. D.; SILVA FILHO, J. M.; OLIVEIRA, M. M. N. F.; CARVALHO, G. R.; FONSECA, J. F. da..
Resumo: Estudou-se o efeito do Hormônio do Crescimento bovino (bGH) sobre os parâmetros seminais e a concentração sérica de testosterona de touros da raça Nelore. Dezesseis touros foram distribuídos em um delineamento fatorial 2 x 2 (duas idades e dois níveis de r-bST), com quatro animais em cada tratamento. As aplicações de r-bST foram realizadas a cada 14 dias, totalizando nove aplicações por animal, em um período experimental de 120 dias. As coletas de sêmen foram realizadas a cada 15 dias e, para determinar as concentrações de testosterona, foram realizadas coletas de sangue a cada quatro horas, num total de 24 horas, e a cada 30 dias a partir da primeira aplicação de r-bST. O sêmen dos touros adultos tratados com r-bST apresentaram maior motilidade e...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Somatotrofina bovina recombinante; R-bST; Recombinant bovine Somatotropin; Touro; Hormônio animal; Sêmen; Testosterona; Bulls; Hormones; Testosterone; Semen.
Ano: 2015 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1016114
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