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	Provedor de dados 55 (3) 56 (2) Autor Andrade,Luis Jesuíno de Oliveira (1) Aquino,E.M. (1) Atta,Ajax Mercês (1) Barut,Sener (1) Bensenor,I.M. (1) Campos,D. (1) D'Almeida Junior,Argemiro (1) Deng,Hong (1) Erkorkmaz,Unal (1) Figueiredo,R.C. de (1) Gunal,Ozgur (1) Ji,Fanpu (1) Li,Zongfang (1) Lotufo,P.A. (1) Maciel,B.C. (1) Maciel,L.M.Z. (1) Magalhães,P.K.R. (1) Melato,L.H. (1) Olmos,R.D. (1) Paraná,Raymundo (1) Mais... Palavra-chave Thyroid dysfunction (5) Adverse drug reaction (1) Amiodarone (1) Antiarrhythmic drug (1) Cardiotoxicity (1) Chagas’ disease (1) Chronic hepatitis C (1) Gender (1) Hepatitis C (1) Interferon-alpha (1) Levothyroxine (1) Peginterferon (1) Pegylated interferon (1) Race (1) Ribavirin (1) Socioeconomic status (1) Sustained virologic response (1) Thyroiditis (1) Treatment of thyroid disorders (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Info:eu-repo/semantics/report (1) Ano 2015 (1) 2014 (1) 2012 (1) 2009 (1) 2008 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Dilated cardiomyopathy and hypothyroidism associated with pegylated interferon and ribavirin treatment for chronic hepatitis C: case report and literature review 55 Zhao,Wenxue; Ji,Fanpu; Yu,Shanshan; Li,Zongfang; Deng,Hong. Pegylated interferon alpha (Peg IFN-α) in combination with ribavirin is the backbone of treatment in chronic hepatitis C (CHC). Cardiotoxicity due to interferon therapy is rare. The most frequent cardiovascular complications are arrhythmias and ischemic manifestations. Cardiomyopathy is extremely rare but can be life threatening. We present the case of a 41-year-old female patient with CHC in whom Peg IFN-α induced dilated cardiomyopathy and hypothyroidism. Chest radiography showed an enlarged and globular cardiac silhouette and pulmonary congestion. Echocardiography showed decreased left ventricular systolic function with an ejection fraction of 32% and fractional shortening of 15%. Cardiomyopathy had a complete remission after cessation of antiviral... Tipo: Info:eu-repo/semantics/report Palavras-chave: Pegylated interferon; Adverse drug reaction; Cardiotoxicity; Thyroid dysfunction. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100110 Gender, race and socioeconomic influence on diagnosis and treatment of thyroid disorders in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) 56 Olmos,R.D.; Figueiredo,R.C. de; Aquino,E.M.; Lotufo,P.A.; Bensenor,I.M.. Thyroid diseases are common, and use of levothyroxine is increasing worldwide. We investigated the influence of gender, race and socioeconomic status on the diagnosis and treatment of thyroid disorders using data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), a multicenter cohort study of civil servants (35-74 years of age) from six Brazilian cities. Diagnosis of thyroid dysfunction was by thyrotropin (TSH), and free thyroxine (FT4) if TSH was altered, and the use of specific medications. Multivariate logistic regression models were constructed using overt hyperthyroidism/hypothyroidism and levothyroxine use as dependent variables and sociodemographic characteristics as independent variables. The frequencies of overt hyper- and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Thyroid dysfunction; Treatment of thyroid disorders; Levothyroxine; Gender; Socioeconomic status; Race. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000800751 How frequently should a patient taking amiodarone be screened for thyroid dysfunction? 56 Pazin-Filho,A.; de Jesus,A.M.X.; Magalhães,P.K.R.; Melato,L.H.; Campos,D.; Maciel,B.C.; Maciel,L.M.Z.. Amiodarone-induced thyroid dysfunction (AITD) is a common complication of amiodarone therapy and its prevalence varies according to iodine intake, subclinical thyroid disorders and the definition of AITD. There is no consensus about the frequency of screening for this condition. We evaluated 121 patients on chronic regular intake of amiodarone (mean intake = 248.5 ± 89 mg; duration of treatment = 5.3 ± 3.9 years, range = 0.57-17 years) and with stable baseline cardiac condition. Those with no AITD were followed up for a median period of 3.2 years (range: 0.6-6.7) and the incidence rate of AITD, defined by clinical and laboratorial findings as proposed by international guidelines, was obtained (62.8 per 1000 patients/year). We applied the Cox proportional... Tipo: Info:eu-repo/semantics/article Palavras-chave: Amiodarone; Chagas’ disease; Thyroid dysfunction; Antiarrhythmic drug. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800009 Thyroid dysfunction in hepatitis C individuals treated with interferon-alpha and ribavirin: a review 55 Andrade,Luis Jesuíno de Oliveira; Atta,Ajax Mercês; D'Almeida Junior,Argemiro; Paraná,Raymundo. Hepatitis C (HCV) is now the main cause of chronic hepatic disease, cirrhosis and hepatocellular carcinoma. Several extrahepatic diseases have been associated with chronic HCV infection, and in most cases appear to be directly related to the viral infection. Thyroid disorders are common in patients with chronic HCV. Some patients with chronic hepatitis C experience thyroid problems, and thyroid dysfunction may also be a side effect of interferon-based treatment. The principal risk factor for developing thyroid disease in the course of antiviral therapy is the previous positivity for anti-thyroid antibodies (anti-thyroid peroxidase) especially in older women. Screening for autoantibodies and serum thyroid-stimulating hormone is recommended before, during... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Interferon-alpha; Ribavirin; Thyroid dysfunction; Thyroiditis. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200009 Thyroid dysfunction in Turkish patients with chronic hepatitis C receiving peginterferon plus ribavirin in the period of 2005-2010 55 Barut,Sener; Gunal,Ozgur; Erkorkmaz,Unal; Yildiz,Feyza. Interferon-α based therapy for chronic hepatitis C (CHC) is associated with thyroiditis and thyroid dysfunction (TD). This study investigated whether TD during pegylated interferon-a (PEG-IFN) plus ribavirin treatment favors sustained viral response (SVR), and also the association between TD and PEG-IFN formulations. This retrospective study was performed in CHC patients who had received PEG-IFN plus ribavirin and had been followed for six months after treatment. Several factors were compared between patients with and without TD. 119 patients were included in the study. De novo incidence of TD was found to be 16.8%, and 16 of the 18 patients with TD achieved SVR. Although this rate was higher than patients without TD according to univariate analysis,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic hepatitis C; Peginterferon; Thyroid dysfunction; Sustained virologic response. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000500008 Registros recuperados: 5 Primeira ... 1 ... Última

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