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Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs J. Venom. Anim. Toxins incl. Trop. Dis.
Camplesi,AC; Sakate,M; Simão,NMB; Marucio,R; Mota,FCD; Moya-Araujo,CF.
Accidents involving toad poisoning are frequent and dogs are the most common victims; they become poisoned by biting or ingesting a toad. When released in the organism, the venom is absorbed by both the oral mucosa and the digestive tract, initiating its toxic action. The aim of this work was to evaluate the clinical and electrocardiographic aspects of dogs subjected to experimental toad poisoning, as well as their response to treatment with propranolol. Twenty dogs were divided into two groups, a control group (n = 5) and a poisoned group (n = 15). After general anesthesia, the control group received a placebo, while the poisoned group received a venom aliquot through an orogastric tube. Results were tested through multivariate analysis (p < 0.05). The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Dogs; Toad venom; Poisoning; Bufotoxin; Arrhythmias.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200014
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Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad J. Venom. Anim. Toxins incl. Trop. Dis.
Rostelato-Ferreira,Sandro; Belo,Cháriston A Dal; Leite,Gildo B; Hyslop,Stephen; Rodrigues-Simioni,Léa.
BackgroundRhinella schneideri, previously known as Bufo paracnemis, is a common toad in many regions of Brazil. Its venom exerts important cardiovascular effects on humans and other animals. Although this toad venom has been the subject of intense investigations, little is known about its neuromuscular activity.MethodsThe neurotoxicity of a methanolic extract of R. schneideri venom was tested on mouse phrenic nerve-diaphragm (PND) preparations mounted for conventional twitch tension recording – in response to indirect stimulation – and for electrophysiological measurements.ResultsVenom extract (50 μg/mL) increased the muscle twitch tension in PND preparations but did not significantly alter the resting membrane potential values. Electrophysiological...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neurotransmitter release; Ouabain; Presynaptic; Rhinella schneideri; Toad venom.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200332
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Toad poisoning in three dogs: case reports J. Venom. Anim. Toxins incl. Trop. Dis.
Barbosa,CM; Medeiros,MS; Riani Costa,CCM; Camplesi,AC; Sakate,M..
Toad poisoning is frequent in dogs, but has been infrequently addressed in published case reports and review articles. Dogs can be poisoned when they bite a toad or otherwise ingest the venom. The venom effects manifest soon after the accident, since the toxin is rapidly absorbed by the mucous membrane of the digestive system. Hospital records of three dogs, diagnosed with toad poisoning, were retrospectively reviewed from January 2005 to July 2007. Poisoned dogs may present only local irritation or systemic signs in the gastrointestinal, cardiac and neurological systems. All three cases presented herein had clinical signs of gastrointestinal alterations including vomiting, sialorrhea and diarrhea. Two dogs developed abnormal cardiac rhythm and two...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Veterinary emergency; Poisoning; Toad venom; Bufotoxin; Bufo sp.; Dog.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000400016
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