Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados Biocell (1) BJMBR (1) Autor Manucha,Walter (1) Ning,Wangbin (1) Wang,Xuan (1) Xie,Tingting (1) Yang,Hui (1) Zhang,Weiru (1) Mais... Palavra-chave Unilateral ureteral obstruction (2) Angiotensin II (1) Apoptosis (1) Enalapril (1) Fluorofenidone (1) Interstitial fibrosis (1) Nitric oxide (1) Oxidative stress (1) Renal fibrosis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2007 (1) País Argentina (1) Brazil (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Biochemical-molecular markers in unilateral ureteral obstruction Biocell Manucha,Walter. Congenital obstructive nephropathy is the primary cause of end-stagerenal disease in children. Rapid diagnosis and initiation of the treatment are vital to preserve function and/or to slow down renal injury. Obstr uctive uropathy effects-decline in the plasmatic renal flow and glomerular filtrationrate, interstitial infiltrate of leukocytes, significant decrease of the urine concentration, loss of the capacity to concentrate urine as well as fibrosis and apoptosisare a consequence of a variety of factors that work in complex ways and are still not fully understood. Mediators as angiotensin II, transforming growth factor-b (TGF-b) and nitric oxide (NO) have been implicated in congenital obstructive nephropathy. The renin-angiotensin system is regulated in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Unilateral ureteral obstruction; Interstitial fibrosis; Nitric oxide; Angiotensin II; Oxidative stress. Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452007000100001 Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis BJMBR Yang,Hui; Zhang,Weiru; Xie,Tingting; Wang,Xuan; Ning,Wangbin. This study aimed to investigate the mechanism of fluorofenidone (AKF-PD) in treating renal interstitial fibrosis in rats with unilateral urinary obstruction (UUO). Thirty-two male Sprague-Dawley rats were randomly divided into sham, UUO, UUO + enalapril, and UUO + AKF-PD groups. All rats, except sham, underwent left urethral obstruction surgery to establish the animal model. Rats were sacrificed 14 days after surgery, and serum was collected for renal function examination. Kidneys were collected to observe pathological changes. Immunohistochemistry was performed to assess collagen I (Col I) protein expression, and terminal deoxynucleotidyl transferase-mediated nick end-labeling staining to observe the apoptosis of renal tubular epithelial cells. The... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fluorofenidone; Unilateral ureteral obstruction; Renal fibrosis; Apoptosis; Enalapril. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001100604 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco