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The Histo-morphometric Evidences of Vernonia amygdalina Leaf Extract-induced Testicular Toxicity International Journal of Morphology
Saalu,L. C; Akunna,G. G; Oyewopo,A. O.
Vernonia amygdalina (bitter-leaf) is native to West Africa but occurs mostly in its cultivated form in various parts of central and southern Nigeria. It is a dark-green leafy vegetable commonly used in cooking and as folkloric medicine for the management of several diseases in Nigeria. In the present study, the effects of varying doses of ethanolic leaf extract of Vernonia amygdalina on the rat testis histo-morphometry were investigated. Forty male wistar rats were divided into groups of four. Group A, as the control was given 10 ml/kg/day/oral distilled water while Group B, C and D subsequently treated with 100, 300 and 600 mg/kg/day/oral route Vernonia amygdalina leaves extract respectively for 56 days. Results showed that Group B rats had normal testis...
Tipo: Journal article Palavras-chave: Vernonia amygdalina; Histology; Morphometry; Testis; Wistar rat.
Ano: 2013 URL:
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