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Adrenoceptors of the medial septal area modulate water intake and renal excretory function induced by central administration of angiotensin II BJMBR
Saad,W.A.; Guarda,I.F.M.S.; Camargo,L.A.A.; Santos,T.A.F.B.; Simões,S.; Saad,Willian A..
We investigated the role of a-adrenergic antagonists and clonidine injected into the medial septal area (MSA) on water intake and the decrease in Na+, K+ and urine elicited by ANGII injection into the third ventricle (3rdV). Male Holtzman rats with stainless steel cannulas implanted into the 3rdV and MSA were used. ANGII (12 nmol/µl) increased water intake (12.5 ± 1.7 ml/120 min). Clonidine (20 nmol/µl) injected into the MSA reduced the ANGII-induced water intake (2.9 ± 0.5 ml/120 min). Pretreatment with 80 nmol/µl yohimbine or prazosin into the MSA also reduced the ANGII-induced water intake (3.0 ± 0.4 and 3.1 ± 0.2 ml/120 min, respectively). Yohimbine + prazosin + clonidine injected into the MSA abolished the ANGII-induced water intake (0.2 ± 0.1 and 0.2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: A-Adrenoceptors; Angiotensin II; Water intake; Sodium; Potassium; Water excretion; Medial septal area.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800012
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Antidipsogenic effects of central adenosine-5'-triphosphate BJMBR
de Faria,D.R.G.; Santana,J.S.; Menani,J.V.; de Paula,P.M..
Besides other physiological functions, adenosine-5'-triphosphate (ATP) is also a neurotransmitter that acts on purinergic receptors. In spite of the presence of purinergic receptors in forebrain areas involved with fluid-electrolyte balance, the effect of ATP on water intake has not been investigated. Therefore, we studied the effects of intracerebroventricular (icv) injections of ATP (100, 200 and 300 nmol/µL) alone or combined with DPCPX or PPADS (P1 and P2 purinergic antagonists, respectively, 25 nmol/µL) on water intake induced by water deprivation. In addition, the effect of icv ATP was also tested on water intake induced by intragastric load of 12% NaCl (2 mL/rat), acute treatment with the diuretic/natriuretic furosemide (20 mg/kg), icv angiotensin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Water intake; ATP icv; Purinergic receptors; Angiotensin II; Carbachol; Ingestive behavior.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000100015
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Apparent digestibility of diets with combinations of soybean hulls and coastcross (Cynodon sp.) hay offered to ram lambs Scientia Agricola
Araujo,Rafael Canonenco de; Pires,Alexandre Vaz; Susin,Ivanete; Urano,Fumi Shibata; Mendes,Clayton Quirino; Rodrigues,Gustavo Henrique; Packer,Irineu Umberto.
Soybean hulls (SH) are an alternative fiber source that may be used to maintain neutral detergent fiber (NDF) concentration while increasing the energy concentration of ruminant diets. The objective of this experiment was to determine the effects of replacing coastcross (Cynodon sp.) hay NDF by SH NDF on the apparent digestibility of nutrients and nitrogen balance of Santa Inês ram lambs. Twenty-four animals (42.5 ± 3.6 kg of body weight and six months old) were placed in metabolism crates and assigned in a randomized complete block design defined by body weight (BW). Experimental diets provided a similar concentration of NDF (52%) and crude protein (15%). Hay NDF from a 70% roughage-based diet was replaced with SH NDF by 33%, 67%, and 100%, resulting in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: NDF; Hair sheep; Nitrogen balance; Santa Inês; Water intake.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162008000600003
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Central lead administration inhibits water intake and sodium appetite in rats BJMBR
De-Castro-e-Silva,E.J.; Castro,L.; Luz,C.P.; Ferreira,H.; Lima,A.K.S.; Souza,F.S.F.; Maldonado,I.; Macêdo,D.F.; Ferreira,M.G.; Bandeira,I.P.V.; Amor,A.L.M.; Carvalho,F.L.Q.; Rocha Jr.,M.A.; Fregoneze,J.B..
We have demonstrated that acute third ventricle injections of lead acetate (PbAc) exert a powerful antidipsogenic effect and induce a significant increase in renal sodium excretion. In the present study we confirm the antidipsogenic effect of lead and demonstrate that central administration of this metal, in minute amounts, significantly reduces salt intake both during dehydration and after central angiotensinergic stimulation. Adult male Wistar rats had the third ventricle cannulated seven days before the experiments. During this period they had free access to distilled water and hypertonic saline solution (1.5%). After a 24-h period of fluid deprivation, experimental animals received third ventricle injections of PbAc (0.3, N = 8 and 3.0 nmol/rat, N =...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Lead; Angiotensin II; Water intake; Sodium intake; Rats.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001000011
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Chronic excitotoxic lesion of the dorsal raphe nucleus induces sodium appetite BJMBR
Cavalcante-Lima,H.R.; Badauê-Passos Jr.,D.; de-Lucca Jr.,W.; Lima,H.R.C.; Costa-e-Sousa,R.H.; Olivares,E.L.; Cedraz-Mercez,P.L.; Reis,R.O.; Medeiros,M.A.; Côrtes,W.S.; Reis,L.C..
We determined if the dorsal raphe nucleus (DRN) exerts tonic control of basal and stimulated sodium and water intake. Male Wistar rats weighing 300-350 g were microinjected with phosphate buffer (PB-DRN, N = 11) or 1 µg/0.2 µl, in a single dose, ibotenic acid (IBO-DRN, N = 9 to 10) through a guide cannula into the DRN and were observed for 21 days in order to measure basal sodium appetite and water intake and in the following situations: furosemide-induced sodium depletion (20 mg/kg, sc, 24 h before the experiment) and a low dose of dietary captopril (1 mg/g chow). From the 6th day after ibotenic acid injection IBO-DRN rats showed an increase in sodium appetite (12.0 ± 2.3 to 22.3 ± 4.6 ml 0.3 M NaCl intake) whereas PB-DRN did not exceed 2 ml (P <...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sodium appetite; Water intake; Dorsal raphe nucleus; Serotonergic system; Ibotenic acid.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100015
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Effect of electrolytic lesion of the dorsal raphe nucleus on water intake and sodium appetite BJMBR
Olivares,E.L.; Costa-e-Sousa,R.H.; Cavalcante-Lima,H.R.; Lima,H.R.C.; Cedraz-Mercez,P.L.; Reis,L.C..
The present study determined the effect of an electrolytic lesion of the dorsal raphe nucleus (DRN) on water intake and sodium appetite. Male Wistar rats weighing 290-320 g with a lesion of the DRN (L-DRN), performed two days before experiments and confirmed by histology at the end of the experiments, presented increased sensitivity to the dehydration induced by fluid deprivation. The cumulative water intake of L-DRN rats reached 23.3 ± 1.9 ml (a 79% increase, N = 9) while sham-lesioned rats (SL-DRN) did not exceed 13.0 ± 1.0 ml (N = 11, P < 0.0001) after 5 h. The L-DRN rats treated with isoproterenol (300 µg kg-1 ml-1, sc) exhibited an increase in water intake that persisted throughout the experimental period (L-DRN, 15.7 ± 1.47 ml, N = 9 vs SL-DRN,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sodium appetite; Water intake; Dorsal raphe nucleus; Serotonergic system; Electrolytic lesion; Rats.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001200013
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Effect of injection of L-NAME on drinking response BJMBR
Saad,W.A.; Camargo,L.A.A.; Saad,R.; Pereira,A.F.; Simões,S..
The drinking behavior responses to centrally administered NG-nitro-L-arginine methyl ester (L-NAME; 10, 20 or 40 µg/µl), an inhibitor of nitric oxide synthase, were studied in satiated rats, with cannulae stereotaxically implanted into the lateral ventricle (LV) and subfornical organ (SFO). Water intake increased in all animals after angiotensin II (ANG II) injection into the LV, with values of 14.2 ± 1.4 ml/h. After injection of L-NAME at doses of 10, 20 or 40 µg/µl into the SFO before injection of ANG II (12 ng/µl) into the LV, water intake decreased progressively and reached basal levels after treatment with 0.15 M NaCl and with the highest dose of L-NAME (i.e., 40 µg). The water intake obtained after 40 µg/µl L-NAME was 0.8 ± 0.01 ml/h. Also, the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitric oxide; Water intake; SFO; Dehydration; CNS.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001100012
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Effect of the intracerebroventricular administration of GR 113808, a selective 5-HT4 antagonist, on water intake during hyperosmolarity and hypovolemia BJMBR
Castro,L.; Varjão,B.; Silva,I.; Duque,B.; Batista,A.; Santana,R.; Luz,P.; Rocha Junior,M.A.; Fregoneze,J.B.; De Castro-e-Silva,E..
We demonstrate here that acute third ventricle injections of GR 113808, a highly selective 5-HT4 antagonist, decrease water intake induced by a previous salt load while potentiating drinking elicited by hypovolemia induced by previous subcutaneous administration of polyethylene glycol in male Wistar rats (200 ± 20 g). At the dose of 160 nmol/rat, third ventricle injections of GR 113808 induced a significant reduction of water intake in salt-loaded animals after 120 min as compared to salt-loaded animals receiving third ventricle injections of saline (salt load + GR = 3.44 ± 0.41 ml, N = 12; salt load + saline = 5.74 ± 0.40 ml, N = 9). At the dose of 80 nmol/rat, GR 113808 significantly enhanced water intake in hypovolemic animals after 120 min as compared...
Tipo: Info:eu-repo/semantics/other Palavras-chave: 5-HT4 receptors; Water intake; Hyperosmolarity; Hypovolemia.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600015
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Influence of calcium salts of long chain fatty acids on the intake and digestibility of rations in female kids under heat stress Animal Sciences
Ferrari, Isabella Ribeiro; Alcalde, Claudete Regina; Gomes, Ludmila Couto; Molina, Bruna Susan de Labio; Barbosa, Orlando Rus; Santos, Sérgio Mangano de Almeida.
This study aimed to evaluate the effect of the addition of calcium salts of long chain fatty acids (CSFA) on the intake and digestibility of diets. Twenty-five female goat kids housed in digestibility cages and subjected to heat stress of 32°C in a climatic chamber, were used. The female kids were distributed in a randomized block design with five treatments: control (without inclusion of CSFA) and 6.25; 12.50; 18.75 and 25.00 g CSFA kg-1 of DM. The inclusion of CSFA in rations did not influence water intake (3.08 L day-1), dry matter (0.66 kg day-1), organic matter (0.62 kg day-1), crude protein (0.12 kg day-1), neutral detergent fiber (0.27 kg day-1) and total carbohydrate (0.47 kg day-1). The results of the digestibility of dry matter (0.66 kg kg-1),...
Tipo: Info:eu-repo/semantics/article Palavras-chave: 5.04.03.00-1 goats; Environmental factors; Water intake; Protected fat..
Ano: 2016 URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/29910
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Lead (Pb2+) and cadmium (Cd2+) inhibit the dipsogenic action of central beta-adrenergic stimulation by isoproterenol BJMBR
We have previously demonstrated that acute third ventricle injections of both Pb2+ and Cd2+ impair the dipsogenic response elicited by three different situations: dehydration and central cholinergic or angiotensinergic stimulation. ß-Adrenergic activation is part of the multifactorial integrated systems operating in drinking behavior control in the central nervous system. In the present study acute third ventricle injections of Pb2+ (3, 30 and 300 pmol/rat) or Cd2+ (0.3, 3 and 30 pmol/rat) blocked the dipsogenic response induced by third ventricle injections of isoproterenol (ISO; 160 nmol/rat) in a dose-dependent manner. Normohydrated animals receiving ISO + NaAc (sodium acetate) or saline (controls) displayed a high water intake after 120 min (ISO +...
Palavras-chave: Lead; Cadmium; Water intake; Isoproterenol.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000300018
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Lesions of the commissural subnucleus of the nucleus of the solitary tract increase isoproterenol-induced water intake BJMBR
Blanch,G.T.; Freiria-Oliveira,A.H.; Colombari,E.; Menani,J.V.; Colombari,D.S.A..
The nucleus of the solitary tract (NTS) is the primary site of the cardiovascular afferent information about arterial blood pressure and volume. The NTS projects to areas in the central nervous system involved in cardiovascular regulation and hydroelectrolyte balance, such as the anteroventral third ventricle region and the lateral parabrachial nucleus. The aim of the present study was to investigate the effects of electrolytic lesion of the commissural NTS on water and 0.3 M NaCl intake and the cardiovascular responses to subcutaneous injection of isoproterenol. Male Holtzman rats weighing 280 to 320 g were submitted to sham lesion or electrolytic lesion of the commissural NTS (N = 6-15/group). The sham-lesioned rats had the electrode placed along the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Nucleus of the solitary tract; Commissural nucleus of the rat solitary tract; Water intake; Arterial pressure; Isoproterenol; Hindbrain.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800013
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Opiatergic participation in the thirst-inhibiting effect of acute third ventricle injections of cadmium (Cd2+) and lead (Pb2+) BJMBR
De-Castro-e-Silva,E.; Luz,C.P.; Sarmento,C.; Nascimento,T.; Gonzalez,V.; Marinho,C.A.; Castro,L.; Oliveira,P.; Santana Jr.,P.; De-Oliveira,I.R.; De-Paula,S.; Lima,A.K.S.; Fregoneze,J.B..
We have previously demonstrated that acute third ventricle injections of both lead and cadmium prevent the dipsogenic response elicited by dehydration or by central injections of dipsogenic agents such as angiotensin II, carbachol and isoproterenol in rats. We have also shown that the antidipsogenic action of cadmium may be due, at least in part, to activation of thirst-inhibitory central serotonergic pathways. In the present paper we show that in Wistar male rats the antidipsogenic effect of both lead acetate (3.0 nmol/rat) and cadmium chloride (3.0 nmol/rat) may be partially dependent on the activation of brain opiatergic pathways since central injections of naloxone (82.5 nmol/rat), a non-selective opioid antagonist, blunt the thirst-inhibiting effect...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Cadmium; Lead; Water intake; Opioids; Rats.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600013
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Performance and economic viability of feedlot sheep fed different levels of roughage, concentrate, and water. Repositório Alice
SILVA, C. M. da; ARAUJO, G. G. L. de; OLIVEIRA, B. Y. S. de; AZEVÊDO, J. A. G. de; FURTADO, D. A..
The aim of this study was to evaluate performance and economic viability of producing sheep fed different levels of roughage, concentrate, and water. Forty Santa Inês crossbred sheep with an average initial weight of 18.85 ± 2.80 kg and an average age of 5.0 ± 2.0 months were distributed in a completely randomized design with a 2 × 2 factorial arrangement composed of two proportions of roughage and concentrate (30:70 and 70:30) and two levels of water supply (ad libitum, and 50% restriction), with 10 replicates. Water restriction had a negative effect (P<0.05) on the intakes of dry matter and nutrients and total and daily weight gains, regardless of the proportions of roughage and concentrate. Water restriction did not affect (P>0.05) feed conversion...
Tipo: Artigo em periódico indexado (ALICE) Palavras-chave: Consumo de água; Consumo de alimento; Ganho de peso; Restrição de água; Produção animal; Ovino; Animal produciton; Water intake; Feed intake; Weight gain; Water restriction.
Ano: 2016 URL: http://www.alice.cnptia.embrapa.br/handle/doc/1064880
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Performance of broiler chickens supplemented with Mexican oregano oil (Lippia berlandieri Schauer) R. Bras. Zootec.
Vázquez,Ramón Silva; Meléndez,Lorenzo Antonio Durán; Estrada,Eduardo Santellano; Rodríguez Muela,Carlos; Villalobos,Guillermo Villalobos; Zamora,Gerardo Méndez; Hume,Michael E..
The objective of this research was to evaluate the inclusion of two qualities of Mexican oregano oil (MOO) in broiler diets on broiler weight, feed intake, feed efficiency, average daily gain, and water intake. The qualities were MOO1 (4% thymol, 60% carvacrol) and MOO2 (40% thymol, 20% carvacrol). Nine treatments were prepared by the combinations of MOO1 + MOO2 (0, 400, and 800 mg kg−1; added per kg of feed) respectively: 0+0, 0+400, 0+800, 400+0, 400+400, 400+800, 800+0, 800+400, and 800+800. Eighteen chicks per treatment were divided in a completely randomized design into nine cages. Broiler weights were altered by the treatments at 21 d, when 400+400 had the highest weight, and on day 39, when the greatest weight was seen in broilers on treatments...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Carvacrol; Extract; Inclusion; Thymol; Water intake.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982015000800283
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Role of angiotensin II and vasopressin receptors within the supraoptic nucleus in water and sodium intake induced by the injection of angiotensin II into the medial septal area BJMBR
Antunes,V.R.; Camargo,G.M.P.A.; Saad,R.; Saad,W.A.; Luiz,A.C.; Camargo,L.A.A..
In this study we investigated the effects of the injection into the supraoptic nucleus (SON) of non-peptide AT1- and AT2-angiotensin II (ANG II) receptor antagonists, DuP753 and PD123319, as well as of the arginine-vasopressin (AVP) receptor antagonist d(CH2)5-Tyr(Me)-AVP, on water and 3% NaCl intake induced by the injection of ANG II into the medial septal area (MSA). The effects on water or 3% NaCl intake were assessed in 30-h water-deprived or in 20-h water-deprived furosemide-treated adult male rats, respectively. The drugs were injected in 0.5 µl over 30-60 s. Controls were injected with a similar volume of 0.15 M NaCl. Antagonists were injected at doses of 20, 80 and 180 nmol. Water and sodium intake was measured over a 2-h period. Previous...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Angiotensin II; AT1 receptors; AT2 receptors; V1 receptors; Water intake; Sodium intake; Medial septal area; Supraoptic nucleus; Rats.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001200013
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Water intake and digestive metabolism of broilers fed all-vegetable diets containing acidulated soybean soapstock Rev. Bras. Ciênc. Avic.
Vieira,SL; Viola,ES; Berres,J; Coneglian,JLB; Freitas,DM; Bortolini,TCK.
A study was conducted to compare live performance and digestive metabolism of broiler chickens fed all-vegetable diets (All-Veg) compared to a regular diet including animal by-products. Three feeds were formulated and provided to broilers according to the feeding program: pre-starter from 1 to 10 days, starter from 11 to 21 days, and grower from 21 to 35 days. All feeds had corn and soybean meal as major ingredients; however, two of them were all-vegetable diets having either Degummed Soybean Oil (DSO) or Acidulated Soybean Soapstock (ASS) as fat sources. The third diet included poultry by-product and poultry fat. A total number of 360 day-old broiler chicks were allocated to 1m² battery cages, 10 chicks in each, and 12 replicates per treatment. Live...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acidulated soybean soapstock; All vegetable diets; Broiler; Metabolizability; Water intake.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2006000300004
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