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	Provedor de dados 17 (3,453) Autor Sierra Rayne (83) Kaya Forest (68) I. C. Baianu (42) Rodrick Wallace (42) Amineni Umamaheswari (25) Michael Hucka (16) Michael J. Bucknum (16) Michael E. Baker (15) Nicolas Le Novère (15) Rakesh Sharma (15) Steven J. Koch (15) Boris Shmagin (14) Lawrence J. Herskowitz (14) Nicolas Le Novere (14) Raji Heyrovska (14) Suaib Luqman (14) Bernd Kastenholz (13) James R. White (13) Samuel V. Angiuoli (13) Allen Institute for Brain Science (12) Mais... Palavra-chave Bioinformatics (1,270) Genetics & Genomics (662) Neuroscience (581) Ecology (526) Biotechnology (521) Molecular Cell Biology (457) Earth & Environment (428) Chemistry (422) Evolutionary Biology (382) Cancer (300) Microbiology (281) Pharmacology (264) Plant Biology (241) Data Standards (210) Developmental Biology (193) Immunology (189) Mais... Tipo do documento Manuscript (2,284) Poster (612) Presentation (534) Marker Paper / Data Plan (23) Ano 2012 (242) 2011 (817) 2010 (778) 2009 (723) 2008 (617) 2007 (272) 2006 (4) Mais... País United Kingdom (3,453)		Registro completo Provedor de dados:  17 País:  United Kingdom Título:  Effect of 2-H and 18-O water isotopes in kinesin-1 gliding assay Autores:  Andy Maloney Lawrence J. Herskowitz Steven J. Koch Data:  2012-03-20 Ano:  2012 Palavras-chave:  Molecular Cell Biology Resumo:  We show here the effects of heavy-hydrogen water (^2^H~2~O) and heavy-oxygen water (H~2~^18^O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isotopic waters used in the motility solution decreased the gliding speed of microtubules by a maximum of 21% for heavy-hydrogen and 5% for heavy-oxygen water. We discuss possible interpretations of these results and the importance for future studies of water effects on kinesin and microtubules. We also discuss the implication for biomolecular devices incorporating molecular motors. Tipo:  Manuscript Identificador:  http://precedings.nature.com/documents/7004/version/1 oai:nature.com:10101/npre.2012.7004.1 http://hdl.handle.net/10101/npre.2012.7004.1 Fonte:  Nature Precedings Direitos:  Creative Commons Attribution 3.0 License Fechar

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