| Registro completo |
| Provedor de dados: |
OAK
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| País: |
Japan
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| Título: |
Evaluation of Gene Expression in Peripheral Blood Cells as a Potential Biomarker for Enzootic Bovine Leukosis
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| Autores: |
TAWFEEQ, Mohammad Monir
HORIUCHI, Noriyuki
KOBAYASHI, Yoshiyasu
FURUOKA, Hidefumi
INOKUMA, Hisashi
堀内, 雅之
古林, 与志安
古岡, 秀文
猪熊, 壽
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| Data: |
2013
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| Ano: |
2013
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| Palavras-chave: |
Biomarkers
Enzootic bovine leukosis
Gene expression
QRT-PCR
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| Resumo: |
Expression of six selective genes in peripheral blood cells was evaluated as diagnostic biomarkers for enzootic bovine leukosis (EBL) by using 10 EBL and 15 clinically healthy cattle. The clinically healthy cattle generally showed lower gene expression levels. Although wide variations of gene expression were found in some clinical cases of EBL, 4 and 5 among 10 EBL cattle showed higher expression of interleukin 2 receptor gene (IL2R) and Wilms’ tumor gene (WT1), respectively. Expression of IL2R in peripheral blood cells in EBL cattle was statistically increased; however, the lower sensitivity and higher variation in the gene expressions among clinical cases of EBL would be problems as diagnostic biomarkers.
https://www.jstage.jst.go.jp/article/jvms/75/9/75_13-0109/_article/-char/ja/
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| Idioma: |
Inglês
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| Identificador: |
http://ir.obihiro.ac.jp/dspace/handle/10322/3868
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| Editor: |
日本獣医学会
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| Direitos: |
Veterinary Science
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