| Registro completo |
| Provedor de dados: |
Biological Sciences
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| País: |
Brazil
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| Título: |
Protective effects of ethanolic extract from the red algae Amansia multifida on experimental inflammation, nociception and seizure experimental models
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| Autores: |
Aragão, Gislei Frota
Nonato, Dayanne Terra Tenório
Ponte, Edson Lopes da
Sales, Jonathan Rodrigues
Alencar, Daniel Barroso
Sampaio, Silvana Saker
Camelo Chaves, Edna Maria
Assreuy, Ana Maria Sampaio
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| Data: |
2016-12-20
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| Ano: |
2016
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| Palavras-chave: |
Acute inflammatory process
Antinociception
Epilepsy
Red seaweed
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| Resumo: |
This study aimed to investigate the EEAm effect in mice models of nociception, inflammation and in behavioral tests evaluating the central nervous system. EEAm had inhibitory effects in the following tests: acetic acid-induced writhing (78%); formalin (62% - inflammatory phase); open field (46%). EEAm increased the nociceptive latency (56%) in tail flick test and increased the death-latency by 36% in the pentylenetetrazole-induced seizure model. Moreover, EEAm inhibited paw edema (82%) and peritonitis (45%) induced by carrageenan. In conclusion, EEAm presents antinociceptive, anti-inflammatory and anticonvulsant effects involving peripheral and central-acting mechanisms in mice.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/32361
10.4025/actascibiolsci.v38i4.32361
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| Editor: |
Universidade Estadual De Maringá
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| Relação: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/32361/pdf
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/downloadSuppFile/32361/AUTHORS%E2%80%99%20CONTRIBUTIONS
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| Formato: |
application/pdf
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| Fonte: |
Acta Scientiarum. Biological Sciences; v. 38, n. 4 (2016); 465-471
Acta Scientiarum. Biological Sciences; v. 38, n. 4 (2016); 465-471
1807-863X
1679-9283
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| Direitos: |
Direitos autorais 2016 Acta Scientiarum. Biological Sciences
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